KEGG   PATHWAY: ngn02024
Entry
ngn02024                    Pathway                                
Name
Quorum sensing - Nonomuraea gerenzanensis
Description
Quorum sensing (QS) is a regulatory system that allows bacteria to share information about cell density and adjust gene expression accordingly. All QS bacteria produce and release chemical signal molecules called autoinducers (AIs) that increase in concentration as a function of cell density. The most commonly studied AIs belong to one of the following three categories: acylated homoserine lactones, also referred to as AI-1, used by Gram-negative bacteria; peptide signals, used by Gram-positive bacteria; and AI-2, used by both Gram-negative and Gram-positive bacteria. QS can be divided into at least 4 steps: production of AIs by the bacterial cell; release of AIs, either actively or passively, into the surrounding environment; recognition of AIs by specific receptors; and leading to changes in gene regulation once they exceed a threshold concentration. The processes controlled by QS include virulence, competence, conjugation, antibiotic production, motility, sporulation, and biofilm formation.
Class
Cellular Processes; Cellular community - prokaryotes
Pathway map
ngn02024  Quorum sensing
ngn02024

Other DBs
GO: 0009372
Organism
Nonomuraea gerenzanensis [GN:ngn]
Gene
LCN96_20225  3-deoxy-7-phosphoheptulonate synthase class II [KO:K01626] [EC:2.5.1.54]
LCN96_24510  isochorismatase family protein [KO:K20261] [EC:3.3.2.15]
LCN96_49005  response regulator [KO:K07667]
LCN96_30465  response regulator [KO:K07667]
LCN96_13745  APC family permease [KO:K20265]
LCN96_17235  antibiotic biosynthesis monooxygenase [KO:K11530] [EC:5.3.1.32]
LCN96_44190  extracellular solute-binding protein [KO:K02055]
LCN96_49510  ABC transporter substrate-binding protein [KO:K02055]
LCN96_10435  extracellular solute-binding protein [KO:K02055]
LCN96_13555  ABC transporter substrate-binding protein [KO:K02055]
LCN96_44200  ABC transporter permease subunit [KO:K02053]
LCN96_13565  ABC transporter permease [KO:K02053]
LCN96_44195  ABC transporter permease subunit [KO:K02054]
LCN96_13560  ABC transporter permease [KO:K02054]
LCN96_44205  ABC transporter ATP-binding protein [KO:K02052]
LCN96_13550  ABC transporter ATP-binding protein [KO:K02052]
LCN96_54090  ABC transporter substrate-binding protein [KO:K01999]
LCN96_54760  ABC transporter substrate-binding protein [KO:K01999]
LCN96_13135  ABC transporter substrate-binding protein [KO:K01999]
LCN96_18795  ABC transporter substrate-binding protein [KO:K01999]
LCN96_18800  ABC transporter substrate-binding protein [KO:K01999]
LCN96_18810  ABC transporter substrate-binding protein [KO:K01999]
LCN96_23770  ABC transporter substrate-binding protein [KO:K01999]
LCN96_34235  ABC transporter substrate-binding protein [KO:K01999]
LCN96_10665  ABC transporter substrate-binding protein [KO:K01999]
LCN96_40520  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_54100  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_13120  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_18835  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_23765  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_34240  branched-chain amino acid ABC transporter permease [KO:K01997]
LCN96_40515  branched-chain amino acid ABC transporter permease [KO:K01998]
LCN96_54095  branched-chain amino acid ABC transporter permease [KO:K01998]
LCN96_13115  branched-chain amino acid ABC transporter permease [KO:K01998]
LCN96_18830  branched-chain amino acid ABC transporter permease [KO:K01998]
LCN96_23760  branched-chain amino acid ABC transporter permease [KO:K01998]
LCN96_34245  branched-chain amino acid ABC transporter ATP-binding protein/permease [KO:K01995 K01998]
LCN96_40530  ABC transporter ATP-binding protein [KO:K01995]
LCN96_54110  ABC transporter ATP-binding protein [KO:K01995]
LCN96_10675  ABC transporter ATP-binding protein [KO:K01995]
LCN96_18825  ABC transporter ATP-binding protein [KO:K01995]
LCN96_23755  ABC transporter ATP-binding protein [KO:K01995]
LCN96_13130  ABC transporter ATP-binding protein [KO:K01995]
LCN96_40535  ABC transporter ATP-binding protein [KO:K01996]
LCN96_54105  ABC transporter ATP-binding protein [KO:K01996]
LCN96_13125  ABC transporter ATP-binding protein [KO:K01996]
LCN96_18820  ABC transporter ATP-binding protein [KO:K01996]
LCN96_23750  ATP-binding cassette domain-containing protein [KO:K01996]
LCN96_34250  ABC transporter ATP-binding protein [KO:K01996]
LCN96_12965  hypothetical protein [KO:K01728] [EC:4.2.2.2]
LCN96_14720  right-handed parallel beta-helix repeat-containing protein [KO:K01728] [EC:4.2.2.2]
LCN96_31055  pectate lyase [KO:K01728] [EC:4.2.2.2]
LCN96_51995  hypothetical protein [KO:K01728] [EC:4.2.2.2]
LCN96_40495  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_40525  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
LCN96_41830  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
LCN96_42940  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_52520  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
LCN96_54120  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_07125  AMP-binding protein [KO:K01897] [EC:6.2.1.3]
LCN96_07185  acyl-CoA synthetase [KO:K01897] [EC:6.2.1.3]
LCN96_17715  AMP-dependent synthetase/ligase [KO:K01897] [EC:6.2.1.3]
LCN96_19785  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_29515  long-chain fatty acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_28100  acyl--CoA ligase [KO:K01897] [EC:6.2.1.3]
LCN96_37155  Crp/Fnr family transcriptional regulator [KO:K10914]
LCN96_01785  Crp/Fnr family transcriptional regulator [KO:K10914]
LCN96_52040  cellulase family glycosylhydrolase [KO:K01218] [EC:3.2.1.78]
LCN96_25975  ricin-type beta-trefoil lectin domain protein [KO:K01218] [EC:3.2.1.78]
LCN96_17275  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
LCN96_18210  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
LCN96_21035  DMT family transporter [KO:K09936]
LCN96_21040  DMT family transporter [KO:K09936]
LCN96_52650  ABC transporter substrate-binding protein [KO:K15580]
LCN96_52645  ABC transporter permease [KO:K15581]
LCN96_52640  ABC transporter permease [KO:K15582]
LCN96_52635  ABC transporter ATP-binding protein [KO:K15583]
LCN96_13820  ABC transporter ATP-binding protein [KO:K15583]
LCN96_52630  dipeptide ABC transporter ATP-binding protein [KO:K10823]
LCN96_36575  ABC transporter substrate-binding protein [KO:K02035]
LCN96_41410  ABC transporter substrate-binding protein [KO:K02035]
LCN96_44790  peptide ABC transporter substrate-binding protein [KO:K02035]
LCN96_46240  ABC transporter substrate-binding protein [KO:K02035]
LCN96_46285  ABC transporter substrate-binding protein [KO:K02035]
LCN96_51670  ABC transporter substrate-binding protein [KO:K02035]
LCN96_53555  ABC transporter substrate-binding protein [KO:K02035]
LCN96_03255  ABC transporter substrate-binding protein [KO:K02035]
LCN96_08145  ABC transporter substrate-binding protein [KO:K02035]
LCN96_11310  ABC transporter substrate-binding protein [KO:K02035]
LCN96_11670  ABC transporter substrate-binding protein [KO:K02035]
LCN96_13805  ABC transporter substrate-binding protein [KO:K02035]
LCN96_19915  ABC transporter substrate-binding protein [KO:K02035]
LCN96_21115  ABC transporter substrate-binding protein [KO:K02035]
LCN96_21640  ABC transporter substrate-binding protein [KO:K02035]
LCN96_25795  ABC transporter substrate-binding protein [KO:K02035]
LCN96_27300  ABC transporter substrate-binding protein [KO:K02035]
LCN96_28490  TIGR04028 family ABC transporter substrate-binding protein [KO:K02035]
LCN96_28885  ABC transporter substrate-binding protein [KO:K02035]
LCN96_33255  ABC transporter substrate-binding protein [KO:K02035]
LCN96_33525  ABC transporter family substrate-binding protein [KO:K02035]
LCN96_34945  ABC transporter substrate-binding protein [KO:K02035]
LCN96_35275  ABC transporter substrate-binding protein [KO:K02035]
LCN96_47210  ABC transporter substrate-binding protein [KO:K02035]
LCN96_36580  ABC transporter permease [KO:K02033]
LCN96_41405  ABC transporter permease [KO:K02033]
LCN96_44785  ABC transporter permease [KO:K02033]
LCN96_47205  ABC transporter permease [KO:K02033]
LCN96_51665  ABC transporter permease [KO:K02033]
LCN96_53550  ABC transporter permease [KO:K02033]
LCN96_03260  ABC transporter permease [KO:K02033]
LCN96_08140  ABC transporter permease [KO:K02033]
LCN96_11320  ABC transporter permease [KO:K02033]
LCN96_11665  ABC transporter permease [KO:K02033]
LCN96_13810  ABC transporter permease [KO:K02033]
LCN96_19910  ABC transporter permease [KO:K02033]
LCN96_21120  ABC transporter permease [KO:K02033]
LCN96_21645  ABC transporter permease [KO:K02033]
LCN96_25800  ABC transporter permease [KO:K02033]
LCN96_27305  ABC transporter permease [KO:K02033]
LCN96_28485  ABC transporter permease [KO:K02033]
LCN96_28890  ABC transporter permease [KO:K02033]
LCN96_33260  ABC transporter permease [KO:K02033]
LCN96_34955  ABC transporter permease [KO:K02033]
LCN96_35270  ABC transporter permease [KO:K02033]
LCN96_46280  ABC transporter permease [KO:K02033]
LCN96_36585  ABC transporter permease [KO:K02034]
LCN96_41400  ABC transporter permease [KO:K02034]
LCN96_44780  ABC transporter permease [KO:K02034]
LCN96_46275  ABC transporter permease [KO:K02034]
LCN96_47200  dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein [KO:K02031 K02034]
LCN96_51660  dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein [KO:K02031 K02034]
LCN96_53545  dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein [KO:K02031 K02034]
LCN96_03265  ABC transporter permease [KO:K02034]
LCN96_08135  dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein [KO:K02031 K02034]
LCN96_11325  ABC transporter permease [KO:K02034]
LCN96_11660  ABC transporter permease [KO:K02034]
LCN96_13815  ABC transporter permease [KO:K02034]
LCN96_19905  ABC transporter permease [KO:K02034]
LCN96_21125  ABC transporter permease [KO:K02034]
LCN96_21650  ABC transporter permease [KO:K02034]
LCN96_25805  ABC transporter permease [KO:K02034]
LCN96_27310  ABC transporter permease [KO:K02034]
LCN96_28480  ABC transporter permease [KO:K02034]
LCN96_28895  dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein [KO:K02031 K02034]
LCN96_33265  ABC transporter permease [KO:K02034]
LCN96_34950  ABC transporter permease [KO:K02034]
LCN96_35280  ABC transporter permease [KO:K02034]
LCN96_41395  ABC transporter ATP-binding protein [KO:K02031]
LCN96_44775  ABC transporter ATP-binding protein [KO:K02031 K02032]
LCN96_46270  ABC transporter ATP-binding protein [KO:K02031]
LCN96_03270  ABC transporter ATP-binding protein [KO:K02031]
LCN96_11330  ABC transporter ATP-binding protein [KO:K02031 K02032]
LCN96_11655  ABC transporter ATP-binding protein [KO:K02031]
LCN96_19900  ABC transporter ATP-binding protein [KO:K02031]
LCN96_21130  ABC transporter ATP-binding protein [KO:K02031]
LCN96_25810  ABC transporter ATP-binding protein [KO:K02031]
LCN96_27315  ABC transporter ATP-binding protein [KO:K02031 K02032]
LCN96_28475  ABC transporter ATP-binding protein [KO:K02031 K02032]
LCN96_34960  ABC transporter ATP-binding protein [KO:K02031]
LCN96_35265  ABC transporter ATP-binding protein [KO:K02031]
LCN96_21655  ABC transporter ATP-binding protein [KO:K02031]
LCN96_36605  ABC transporter ATP-binding protein [KO:K02031 K02032]
LCN96_46265  ABC transporter ATP-binding protein [KO:K02032]
LCN96_47195  ABC transporter ATP-binding protein [KO:K02032]
LCN96_08130  ATP-binding cassette domain-containing protein [KO:K02032]
LCN96_11650  ATP-binding cassette domain-containing protein [KO:K02032]
LCN96_19895  ABC transporter ATP-binding protein [KO:K02032]
LCN96_21135  ATP-binding cassette domain-containing protein [KO:K02032]
LCN96_25815  ABC transporter ATP-binding protein [KO:K02032]
LCN96_28900  ABC transporter ATP-binding protein [KO:K02032]
LCN96_35260  dipeptide ABC transporter ATP-binding protein [KO:K02032]
LCN96_00755  yidC; membrane protein insertase YidC [KO:K03217]
LCN96_56085  yidC; membrane protein insertase YidC [KO:K03217]
LCN96_38465  secD; protein translocase subunit SecD [KO:K12257]
LCN96_04575  secE; preprotein translocase subunit SecE [KO:K03073]
LCN96_36200  secG; preprotein translocase subunit SecG [KO:K03075]
LCN96_04795  secY; preprotein translocase subunit SecY [KO:K03076]
LCN96_16050  secY; preprotein translocase subunit SecY [KO:K03076]
LCN96_36880  yajC; preprotein translocase subunit YajC [KO:K03210]
LCN96_47005  secA2; accessory Sec system translocase SecA2 [KO:K03070] [EC:7.4.2.8]
LCN96_06845  secA; preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
LCN96_47525  ftsY; signal recognition particle-docking protein FtsY [KO:K03110]
LCN96_09875  ffh; signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
LCN96_15940  lantibiotic dehydratase [KO:K20483]
LCN96_25340  lantibiotic dehydratase [KO:K20483]
LCN96_15935  lanthionine synthetase C family protein [KO:K20484]
LCN96_25335  lanthionine synthetase C family protein [KO:K20484]
LCN96_32105  lanthionine synthetase C family protein [KO:K20484]
Compound
C00007  Oxygen
C00009  Orthophosphate
C00059  Sulfate
C00232  Succinate semialdehyde
C00334  4-Aminobutanoate
C00547  L-Noradrenaline
C00788  L-Adrenaline
C01019  L-Fucose
C11837  N-Butyryl-L-homoserine lactone
C11841  N-(3-Oxooctanoyl)homoserine lactone
C11844  N-Heptanoylhomoserine lactone
C11845  N-(3-Hydroxy-7-cis-tetradecenoyl)homoserine lactone
C11848  2-Heptyl-3-hydroxy-quinolone
C16421  AI-2
C16463  3',5'-Cyclic diGMP
C16640  CAI-1
C18049  N-Acyl-L-homoserine lactone
C18206  cis-11-Methyl-2-dodecenoic acid
C20643  2-Heptyl-4(1H)-quinolone
C20677  N-(4-Coumaroyl)-L-homoserine lactone
C20959  (4S)-4-Hydroxy-5-phosphooxypentane-2,3-dione
C21195  N-(3-Hydroxybutanoyl)-L-homoserine lactone
C21197  N-Hexanoyl-L-homoserine lactone
C21198  N-(3-Oxohexanoyl)-L-homoserine lactone
C21199  N-Octanoyl-L-homoserine lactone
C21200  N-3-Hydroxyoctanoyl-L-homoserine lactone
C21201  N-3-Oxo-dodecanoyl-L-homoserine lactone
C21202  cis-2-Dodecenoic acid
C21220  AIP-1
C21221  CSP
C21222  CSP
C21223  Blp
C21224  SHP2
C21225  SHP3
C21226  cCF10
C21227  iCF10
C21228  cAD1
C21229  iAD1
C21230  ComX pheromone
C21231  PhrA pentapeptide
C21232  PhrC pentapeptide
C21233  PhrE pentapeptide
C21234  PhrF pentapeptide
C21235  PhrG pentapeptide
C21236  PhrH pentapeptide
C21237  PhrK pentapeptide
C21238  NprX peptide
C21239  PapR peptide
C21241  AIP-2
C21242  AIP-3
C21243  AIP-4
C21244  AgrD peptide
C21245  AgrD1 peptide
C21246  GBAP
C21382  R-THMF
Reference
PMID:22712853
  Authors
Pereira CS, Thompson JA, Xavier KB
  Title
AI-2-mediated signalling in bacteria.
  Journal
FEMS Microbiol Rev 37:156-81 (2013)
DOI:10.1111/j.1574-6976.2012.00345.x
Reference
PMID:23965960
  Authors
Verma SC, Miyashiro T
  Title
Quorum sensing in the squid-Vibrio symbiosis.
  Journal
Int J Mol Sci 14:16386-401 (2013)
DOI:10.3390/ijms140816386
Reference
PMID:24348467
  Authors
Norsworthy AN, Visick KL
  Title
Gimme shelter: how Vibrio fischeri successfully navigates an animal's multiple environments.
  Journal
Front Microbiol 4:356 (2013)
DOI:10.3389/fmicb.2013.00356
Reference
PMID:24065108
  Authors
Papaioannou E, Utari PD, Quax WJ
  Title
Choosing an appropriate infection model to study quorum sensing inhibition in Pseudomonas infections.
  Journal
Int J Mol Sci 14:19309-40 (2013)
DOI:10.3390/ijms140919309
Reference
PMID:20738404
  Authors
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M
  Title
Quinolones: from antibiotics to autoinducers.
  Journal
FEMS Microbiol Rev 35:247-74 (2011)
DOI:10.1111/j.1574-6976.2010.00247.x
Reference
PMID:25866808
  Authors
Rasamiravaka T, Labtani Q, Duez P, El Jaziri M
  Title
The formation of biofilms by Pseudomonas aeruginosa: a review of the natural and synthetic compounds interfering with control mechanisms.
  Journal
Biomed Res Int 2015:759348 (2015)
DOI:10.1155/2015/759348
Reference
PMID:11544214
  Authors
Whiteley M, Greenberg EP
  Title
Promoter specificity elements in Pseudomonas aeruginosa quorum-sensing-controlled genes.
  Journal
J Bacteriol 183:5529-34 (2001)
DOI:10.1128/JB.183.19.5529-5534.2001
Reference
PMID:11497469
  Authors
Chin-A-Woeng TF, van den Broek D, de Voer G, van der Drift KM, Tuinman S, Thomas-Oates JE, Lugtenberg BJ, Bloemberg GV
  Title
Phenazine-1-carboxamide production in the biocontrol strain Pseudomonas chlororaphis PCL1391 is regulated by multiple factors secreted into the growth medium.
  Journal
Mol Plant Microbe Interact 14:969-79 (2001)
DOI:10.1094/MPMI.2001.14.8.969
Reference
PMID:19696934
  Authors
Hughes DT, Clarke MB, Yamamoto K, Rasko DA, Sperandio V
  Title
The QseC adrenergic signaling cascade in Enterohemorrhagic E. coli (EHEC).
  Journal
PLoS Pathog 5:e1000553 (2009)
DOI:10.1371/journal.ppat.1000553
Reference
PMID:22144490
  Authors
Njoroge J, Sperandio V
  Title
Enterohemorrhagic Escherichia coli virulence regulation by two bacterial adrenergic kinases, QseC and QseE.
  Journal
Infect Immun 80:688-703 (2012)
DOI:10.1128/IAI.05921-11
Reference
PMID:23160491
  Authors
Pacheco AR, Curtis MM, Ritchie JM, Munera D, Waldor MK, Moreira CG, Sperandio V
  Title
Fucose sensing regulates bacterial intestinal colonization.
  Journal
Nature 492:113-7 (2012)
DOI:10.1038/nature11623
Reference
PMID:22778415
  Authors
Hirakawa H, Harwood CS, Pechter KB, Schaefer AL, Greenberg EP
  Title
Antisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expression.
  Journal
Proc Natl Acad Sci U S A 109:12141-6 (2012)
DOI:10.1073/pnas.1200243109
Reference
PMID:14617175
  Authors
Danino VE, Wilkinson A, Edwards A, Downie JA
  Title
Recipient-induced transfer of the symbiotic plasmid pRL1JI in Rhizobium leguminosarum bv. viciae is regulated by a quorum-sensing relay.
  Journal
Mol Microbiol 50:511-25 (2003)
DOI:10.1046/j.1365-2958.2003.03699.x
Reference
PMID:12448738
  Authors
Wisniewski-Dye F, Downie JA
  Title
Quorum-sensing in Rhizobium.
  Journal
Antonie Van Leeuwenhoek 81:397-407 (2002)
DOI:10.1023/A:1020501104051
Reference
PMID:10368158
  Authors
Rodelas B, Lithgow JK, Wisniewski-Dye F, Hardman A, Wilkinson A, Economou A, Williams P, Downie JA
  Title
Analysis of quorum-sensing-dependent control of rhizosphere-expressed (rhi) genes in Rhizobium leguminosarum bv. viciae.
  Journal
J Bacteriol 181:3816-23 (1999)
DOI:10.1128/JB.181.12.3816-3823.1999
Reference
PMID:24550924
  Authors
Lang J, Faure D
  Title
Functions and regulation of quorum-sensing in Agrobacterium tumefaciens.
  Journal
Front Plant Sci 5:14 (2014)
DOI:10.3389/fpls.2014.00014
Reference
PMID:23710277
  Authors
Planamente S, Morera S, Faure D
  Title
In planta fitness-cost of the Atu4232-regulon encoding for a selective GABA-binding sensor in Agrobacterium.
  Journal
Commun Integr Biol 6:e23692 (2013)
DOI:10.4161/cib.23692
Reference
PMID:16943991
  Authors
Barnard AM, Salmond GP
  Title
Quorum sensing in Erwinia species.
  Journal
Anal Bioanal Chem 387:415-23 (2007)
DOI:10.1007/s00216-006-0701-1
Reference
PMID:17360277
  Authors
Barnard AM, Bowden SD, Burr T, Coulthurst SJ, Monson RE, Salmond GP
  Title
Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria.
  Journal
Philos Trans R Soc Lond B Biol Sci 362:1165-83 (2007)
DOI:10.1098/rstb.2007.2042
Reference
PMID:19843225
  Authors
Carlier A, Burbank L, von Bodman SB
  Title
Identification and characterization of three novel EsaI/EsaR quorum-sensing controlled stewartan exopolysaccharide biosynthetic genes in Pantoea stewartii ssp. stewartii.
  Journal
Mol Microbiol 74:903-13 (2009)
DOI:10.1111/j.1365-2958.2009.06906.x
Reference
PMID:7665477
  Authors
Beck von Bodman S, Farrand SK
  Title
Capsular polysaccharide biosynthesis and pathogenicity in Erwinia stewartii require induction by an N-acylhomoserine lactone autoinducer.
  Journal
J Bacteriol 177:5000-8 (1995)
DOI:10.1128/JB.177.17.5000-5008.1995
Reference
PMID:19761612
  Authors
O'Grady EP, Viteri DF, Malott RJ, Sokol PA
  Title
Reciprocal regulation by the CepIR and CciIR quorum sensing systems in Burkholderia cenocepacia.
  Journal
BMC Genomics 10:441 (2009)
DOI:10.1186/1471-2164-10-441
Reference
PMID:16041013
  Authors
Malott RJ, Baldwin A, Mahenthiralingam E, Sokol PA
  Title
Characterization of the cciIR quorum-sensing system in Burkholderia cenocepacia.
  Journal
Infect Immun 73:4982-92 (2005)
DOI:10.1128/IAI.73.8.4982-4992.2005
Reference
PMID:22949660
  Authors
Deng Y, Schmid N, Wang C, Wang J, Pessi G, Wu D, Lee J, Aguilar C, Ahrens CH, Chang C, Song H, Eberl L, Zhang LH
  Title
Cis-2-dodecenoic acid receptor RpfR links quorum-sensing signal perception with regulation of virulence through cyclic dimeric guanosine monophosphate turnover.
  Journal
Proc Natl Acad Sci U S A 109:15479-84 (2012)
DOI:10.1073/pnas.1205037109
Reference
PMID:23799665
  Authors
Suppiger A, Schmid N, Aguilar C, Pessi G, Eberl L
  Title
Two quorum sensing systems control biofilm formation and virulence in members of the Burkholderia cepacia complex.
  Journal
Virulence 4:400-9 (2013)
DOI:10.4161/viru.25338
Reference
PMID:21166386
  Authors
Deng Y, Wu J, Tao F, Zhang LH
  Title
Listening to a new language: DSF-based quorum sensing in Gram-negative bacteria.
  Journal
Chem Rev 111:160-73 (2011)
DOI:10.1021/cr100354f
Reference
PMID:21227698
  Authors
Ryan RP, Dow JM
  Title
Communication with a growing family: diffusible signal factor (DSF) signaling in bacteria.
  Journal
Trends Microbiol 19:145-52 (2011)
DOI:10.1016/j.tim.2010.12.003
Reference
PMID:15522077
  Authors
Kim J, Kim JG, Kang Y, Jang JY, Jog GJ, Lim JY, Kim S, Suga H, Nagamatsu T, Hwang I
  Title
Quorum sensing and the LysR-type transcriptional activator ToxR regulate toxoflavin biosynthesis and transport in Burkholderia glumae.
  Journal
Mol Microbiol 54:921-34 (2004)
DOI:10.1111/j.1365-2958.2004.04338.x
Reference
PMID:17376080
  Authors
Kim J, Kang Y, Choi O, Jeong Y, Jeong JE, Lim JY, Kim M, Moon JS, Suga H, Hwang I
  Title
Regulation of polar flagellum genes is mediated by quorum sensing and FlhDC in Burkholderia glumae.
  Journal
Mol Microbiol 64:165-79 (2007)
DOI:10.1111/j.1365-2958.2007.05646.x
Reference
PMID:21622734
  Authors
Stauff DL, Bassler BL
  Title
Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor.
  Journal
J Bacteriol 193:3871-8 (2011)
DOI:10.1128/JB.05125-11
Reference
PMID:21504831
  Authors
Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM
  Title
A strategy for antagonizing quorum sensing.
  Journal
Mol Cell 42:199-209 (2011)
DOI:10.1016/j.molcel.2011.04.003
Reference
PMID:16513747
  Authors
Hao G, Burr TJ
  Title
Regulation of long-chain N-acyl-homoserine lactones in Agrobacterium vitis.
  Journal
J Bacteriol 188:2173-83 (2006)
DOI:10.1128/JB.188.6.2173-2183.2006
Reference
PMID:20514483
  Authors
Savka MA, Le PT, Burr TJ
  Title
LasR receptor for detection of long-chain quorum-sensing signals: identification of N-acyl-homoserine lactones encoded by the avsI locus of Agrobacterium vitis.
  Journal
Curr Microbiol 62:101-10 (2011)
DOI:10.1007/s00284-010-9679-1
Reference
PMID:26579084
  Authors
Le KY, Otto M
  Title
Quorum-sensing regulation in staphylococci-an overview.
  Journal
Front Microbiol 6:1174 (2015)
DOI:10.3389/fmicb.2015.01174
Reference
PMID:18851841
  Authors
Queck SY, Jameson-Lee M, Villaruz AE, Bach TH, Khan BA, Sturdevant DE, Ricklefs SM, Li M, Otto M
  Title
RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
  Journal
Mol Cell 32:150-8 (2008)
DOI:10.1016/j.molcel.2008.08.005
Reference
PMID:25714717
  Authors
Darkoh C, DuPont HL, Norris SJ, Kaplan HB
  Title
Toxin synthesis by Clostridium difficile is regulated through quorum signaling.
  Journal
MBio 6:e02569 (2015)
DOI:10.1128/mBio.02569-14
Reference
PMID:25824838
  Authors
Vidal JE, Shak JR, Canizalez-Roman A
  Title
The CpAL quorum sensing system regulates production of hemolysins CPA and PFO to build Clostridium perfringens biofilms.
  Journal
Infect Immun 83:2430-42 (2015)
DOI:10.1128/IAI.00240-15
Reference
PMID:19363118
  Authors
Ohtani K, Yuan Y, Hassan S, Wang R, Wang Y, Shimizu T
  Title
Virulence gene regulation by the agr system in Clostridium perfringens.
  Journal
J Bacteriol 191:3919-27 (2009)
DOI:10.1128/JB.01455-08
Reference
PMID:22736963
  Authors
Li YH, Tian X
  Title
Quorum sensing and bacterial social interactions in biofilms.
  Journal
Sensors (Basel) 12:2519-38 (2012)
DOI:10.3390/s120302519
Reference
PMID:22407687
  Authors
Berg KH, Biornstad TJ, Johnsborg O, Havarstein LS
  Title
Properties and biological role of streptococcal fratricins.
  Journal
Appl Environ Microbiol 78:3515-22 (2012)
DOI:10.1128/AEM.00098-12
Reference
PMID:25475081
  Authors
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Dobler I, Zeng AP
  Title
Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level.
  Journal
J Oral Microbiol 6:26189 (2014)
DOI:10.3402/jom.v6.26189
Reference
PMID:25309879
  Authors
Jimenez JC, Federle MJ
  Title
Quorum sensing in group A Streptococcus.
  Journal
Front Cell Infect Microbiol 4:127 (2014)
DOI:10.3389/fcimb.2014.00127
Reference
PMID:24118108
  Authors
Cook LC, Federle MJ
  Title
Peptide pheromone signaling in Streptococcus and Enterococcus.
  Journal
FEMS Microbiol Rev 38:473-92 (2014)
DOI:10.1111/1574-6976.12046
Reference
PMID:9680220
  Authors
Podbielski A, Leonard BA
  Title
The group A streptococcal dipeptide permease (Dpp) is involved in the uptake of essential amino acids and affects the expression of cysteine protease.
  Journal
Mol Microbiol 28:1323-34 (1998)
DOI:10.1046/j.1365-2958.1998.00898.x
Reference
PMID:8885277
  Authors
Podbielski A, Pohl B, Woischnik M, Korner C, Schmidt KH, Rozdzinski E, Leonard BA
  Title
Molecular characterization of group A streptococcal (GAS) oligopeptide permease (opp) and its effect on cysteine protease production.
  Journal
Mol Microbiol 21:1087-99 (1996)
DOI:10.1046/j.1365-2958.1996.661421.x
Reference
PMID:22636768
  Authors
Anbalagan S, Dmitriev A, McShan WM, Dunman PM, Chaussee MS
  Title
Growth phase-dependent modulation of Rgg binding specificity in Streptococcus pyogenes.
  Journal
J Bacteriol 194:3961-71 (2012)
DOI:10.1128/JB.06709-11
Reference
PMID:22016844
  Authors
Clewell DB
  Title
Tales of conjugation and sex pheromones: A plasmid and enterococcal odyssey.
  Journal
Mob Genet Elements 1:38-54 (2011)
DOI:10.4161/mge.1.1.15409
Reference
PMID:20734751
  Authors
Wardal E, Sadowy E, Hryniewicz W
  Title
Complex nature of enterococcal pheromone-responsive plasmids.
  Journal
Pol J Microbiol 59:79-87 (2010)
Reference
PMID:19683678
  Authors
Roux A, Payne SM, Gilmore MS
  Title
Microbial telesensing: probing the environment for friends, foes, and food.
  Journal
Cell Host Microbe 6:115-24 (2009)
DOI:10.1016/j.chom.2009.07.004
Reference
PMID:25089349
  Authors
Slamti L, Perchat S, Huillet E, Lereclus D
  Title
Quorum sensing in Bacillus thuringiensis is required for completion of a full infectious cycle in the insect.
  Journal
Toxins (Basel) 6:2239-55 (2014)
DOI:10.3390/toxins6082239
Reference
PMID:20030732
  Authors
Lopez D, Kolter R
  Title
Extracellular signals that define distinct and coexisting cell fates in Bacillus subtilis.
  Journal
FEMS Microbiol Rev 34:134-49 (2010)
DOI:10.1111/j.1574-6976.2009.00199.x
Reference
PMID:12897006
  Authors
Stephenson S, Mueller C, Jiang M, Perego M
  Title
Molecular analysis of Phr peptide processing in Bacillus subtilis.
  Journal
J Bacteriol 185:4861-71 (2003)
DOI:10.1128/JB.185.16.4861-4871.2003
Reference
PMID:17666034
  Authors
Lanigan-Gerdes S, Dooley AN, Faull KF, Lazazzera BA
  Title
Identification of subtilisin, Epr and Vpr as enzymes that produce CSF, an extracellular signalling peptide of Bacillus subtilis.
  Journal
Mol Microbiol 65:1321-33 (2007)
DOI:10.1111/j.1365-2958.2007.05869.x
Reference
PMID:15374644
  Authors
Kleerebezem M
  Title
Quorum sensing control of lantibiotic production; nisin and subtilin autoregulate their own biosynthesis.
  Journal
Peptides 25:1405-14 (2004)
DOI:10.1016/j.peptides.2003.10.021
Reference
PMID:23125205
  Authors
Rutherford ST, Bassler BL
  Title
Bacterial quorum sensing: its role in virulence and possibilities for its control.
  Journal
Cold Spring Harb Perspect Med 2:a012427 (2012)
DOI:10.1101/cshperspect.a012427
Reference
PMID:23471618
  Authors
LaSarre B, Federle MJ
  Title
Exploiting quorum sensing to confuse bacterial pathogens.
  Journal
Microbiol Mol Biol Rev 77:73-111 (2013)
DOI:10.1128/MMBR.00046-12
Reference
PMID:18781869
  Authors
Sifri CD
  Title
Healthcare epidemiology: quorum sensing: bacteria talk sense.
  Journal
Clin Infect Dis 47:1070-6 (2008)
DOI:10.1086/592072
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