KEGG   PATHWAY: ocr00230
Entry
ocr00230                    Pathway                                
Name
Purine metabolism - Ochrobactrum sp. MT180101
Class
Metabolism; Nucleotide metabolism
Pathway map
ocr00230  Purine metabolism
ocr00230

Module
ocr_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ocr00230]
ocr_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ocr00230]
ocr_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ocr00230]
ocr_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ocr00230]
ocr_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ocr00230]
ocr_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ocr00230]
ocr_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ocr00230]
Other DBs
GO: 0006163 0042278
Organism
Ochrobactrum sp. MT180101 [GN:ocr]
Gene
HGK82_12725  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HGK82_08270  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
HGK82_02080  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HGK82_01925  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HGK82_03225  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HGK82_04190  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
HGK82_04220  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
HGK82_04215  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
HGK82_03230  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HGK82_10270  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HGK82_10265  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HGK82_04225  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HGK82_04250  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HGK82_10605  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HGK82_08310  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HGK82_04435  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
HGK82_08255  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HGK82_11105  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HGK82_18385  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HGK82_03140  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HGK82_00275  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HGK82_05250  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
HGK82_01535  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
HGK82_01540  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
HGK82_18415  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HGK82_01560  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
HGK82_09580  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
HGK82_02160  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HGK82_17890  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HGK82_05260  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
HGK82_17895  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HGK82_04385  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HGK82_02995  HD family hydrolase [KO:K06952] [EC:3.1.3.89]
HGK82_02930  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HGK82_21525  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HGK82_03480  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HGK82_09955  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HGK82_02820  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
HGK82_21145  ade; adenine deaminase [KO:K01486] [EC:3.5.4.2]
HGK82_10135  TIGR00282 family metallophosphoesterase [KO:K09769] [EC:3.1.4.16]
HGK82_06020  adenylate kinase [KO:K00939] [EC:2.7.4.3]
HGK82_05150  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
HGK82_00360  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
HGK82_00355  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
HGK82_01530  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HGK82_02405  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HGK82_15220  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
HGK82_01525  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
HGK82_01520  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
HGK82_02400  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
HGK82_00950  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HGK82_03925  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HGK82_00945  urease subunit beta [KO:K01429] [EC:3.5.1.5]
HGK82_03920  urease subunit beta [KO:K01429] [EC:3.5.1.5]
HGK82_00935  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HGK82_03915  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HGK82_16530  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ocr00030  Pentose phosphate pathway
ocr00220  Arginine biosynthesis
ocr00250  Alanine, aspartate and glutamate metabolism
ocr00260  Glycine, serine and threonine metabolism
ocr00340  Histidine metabolism
ocr00630  Glyoxylate and dicarboxylate metabolism
ocr00730  Thiamine metabolism
ocr00740  Riboflavin metabolism
ocr00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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