KEGG   PATHWAY: pkm00230
Entry
pkm00230                    Pathway                                
Name
Purine metabolism - Pseudomonas kermanshahensis
Class
Metabolism; Nucleotide metabolism
Pathway map
pkm00230  Purine metabolism
pkm00230

Module
pkm_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pkm00230]
pkm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pkm00230]
pkm_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pkm00230]
pkm_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pkm00230]
pkm_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pkm00230]
pkm_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pkm00230]
pkm_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pkm00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas kermanshahensis [GN:pkm]
Gene
PZ739_25295  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
PZ739_01275  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
PZ739_15830  pgm; phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) [KO:K01835] [EC:5.4.2.2]
PZ739_03705  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
PZ739_07705  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
PZ739_24820  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
PZ739_06235  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
PZ739_05280  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
PZ739_05135  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
PZ739_06240  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
PZ739_27430  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
PZ739_27435  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
PZ739_21495  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
PZ739_18775  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
PZ739_24815  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
PZ739_19845  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
PZ739_17500  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
PZ739_22565  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
PZ739_05800  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PZ739_10380  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
PZ739_01270  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
PZ739_19760  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
PZ739_03230  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
PZ739_03805  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
PZ739_05095  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
PZ739_04370  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
PZ739_26250  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
PZ739_27105  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
PZ739_19940  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
PZ739_19945  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
PZ739_12245  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
PZ739_12250  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
PZ739_12255  (2Fe-2S)-binding protein [KO:K13483]
PZ739_05100  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
PZ739_19955  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
PZ739_27240  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
PZ739_21785  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
PZ739_21795  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
PZ739_08060  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
PZ739_27270  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
PZ739_26870  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
PZ739_06210  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
PZ739_26900  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
PZ739_25140  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
PZ739_24590  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
PZ739_16340  ppnN; nucleotide 5'-monophosphate nucleosidase PpnN [KO:K06966] [EC:3.2.2.10 3.2.2.-]
PZ739_03070  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
PZ739_05520  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
PZ739_06215  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
PZ739_25285  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
PZ739_02060  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
PZ739_23370  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
PZ739_23375  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
PZ739_19985  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
PZ739_19995  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
PZ739_20125  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
PZ739_19990  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
PZ739_15540  bifunctional allantoicase/(S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
PZ739_20000  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
PZ739_10420  ureidoglycolate lyase [KO:K16856] [EC:4.3.2.3]
PZ739_12450  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
PZ739_12445  urease subunit beta [KO:K01429] [EC:3.5.1.5]
PZ739_12440  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
PZ739_04940  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pkm00030  Pentose phosphate pathway
pkm00220  Arginine biosynthesis
pkm00250  Alanine, aspartate and glutamate metabolism
pkm00260  Glycine, serine and threonine metabolism
pkm00340  Histidine metabolism
pkm00630  Glyoxylate and dicarboxylate metabolism
pkm00730  Thiamine metabolism
pkm00740  Riboflavin metabolism
pkm00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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