KEGG   PATHWAY: pnt00230
Entry
pnt00230                    Pathway                                
Name
Purine metabolism - Pseudomonas nitroreducens
Class
Metabolism; Nucleotide metabolism
Pathway map
pnt00230  Purine metabolism
pnt00230

Module
pnt_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:pnt00230]
pnt_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:pnt00230]
pnt_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:pnt00230]
pnt_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:pnt00230]
pnt_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:pnt00230]
pnt_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:pnt00230]
pnt_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:pnt00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas nitroreducens [GN:pnt]
Gene
G5B91_28840  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
G5B91_29580  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
G5B91_02145  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
G5B91_31420  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
G5B91_27175  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
G5B91_22445  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
G5B91_29020  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
G5B91_24700  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
G5B91_25220  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
G5B91_25265  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
G5B91_24695  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
G5B91_31705  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
G5B91_31710  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
G5B91_24395  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
G5B91_18300  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
G5B91_29015  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
G5B91_20390  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
G5B91_11775  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
G5B91_09465  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
G5B91_02140  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
G5B91_13450  DUF1255 family protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
G5B91_05240  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
G5B91_26750  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
G5B91_25290  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
G5B91_25420  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
G5B91_02315  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
G5B91_31305  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
G5B91_00840  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
G5B91_20530  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
G5B91_00835  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
G5B91_20535  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
G5B91_25285  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
G5B91_34445  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
G5B91_14425  nucleoside deaminase [KO:K01487] [EC:3.5.4.3]
G5B91_20545  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
G5B91_31465  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
G5B91_01360  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
G5B91_10475  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
G5B91_10470  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
G5B91_28915  ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
G5B91_22180  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
G5B91_31475  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
G5B91_01875  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
G5B91_23680  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
G5B91_10585  adenylate cyclase [KO:K01768] [EC:4.6.1.1]
G5B91_31170  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
G5B91_29400  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
G5B91_04155  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
G5B91_08465  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
G5B91_00945  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
G5B91_09080  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
G5B91_23675  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
G5B91_29570  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
G5B91_03025  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
G5B91_05940  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
G5B91_23490  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
G5B91_05935  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
G5B91_20590  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
G5B91_20600  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
G5B91_20595  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
G5B91_10425  (S)-ureidoglycine aminohydrolase [KO:K14977] [EC:3.5.3.26]
G5B91_20605  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
G5B91_29085  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
G5B91_29080  urease subunit beta [KO:K01429] [EC:3.5.1.5]
G5B91_29070  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
G5B91_30540  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
pnt00030  Pentose phosphate pathway
pnt00220  Arginine biosynthesis
pnt00250  Alanine, aspartate and glutamate metabolism
pnt00260  Glycine, serine and threonine metabolism
pnt00340  Histidine metabolism
pnt00630  Glyoxylate and dicarboxylate metabolism
pnt00730  Thiamine metabolism
pnt00740  Riboflavin metabolism
pnt00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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