KEGG   PATHWAY: ppa00970
Entry
ppa00970                    Pathway                                
Name
Aminoacyl-tRNA biosynthesis - Komagataella phaffii
Class
Genetic Information Processing; Translation
Pathway map
ppa00970  Aminoacyl-tRNA biosynthesis
ppa00970

Organism
Komagataella phaffii [GN:ppa]
Gene
PAS_chr1-1_0241  Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene [KO:K01885] [EC:6.1.1.17]
PAS_chr1-4_0598  Glutamyl-tRNA synthetase, cytoplasmic [KO:K01885] [EC:6.1.1.17]
PAS_chr2-1_0400  Putative protein similar to bacterial glutamyl-tRNA amidotransferases [KO:K02433] [EC:6.3.5.6 6.3.5.7]
PAS_chr4_0705  Protein required for mitochondrial translation [KO:K02434] [EC:6.3.5.6 6.3.5.7]
PAS_chr4_0715  Putative protein of unknown function [KO:K03865] [EC:6.3.5.7]
PAS_chr3_0285  Glutamine tRNA synthetase [KO:K01886] [EC:6.1.1.18]
PAS_chr3_0462  Cytoplasmic alanyl-tRNA synthetase [KO:K01872] [EC:6.1.1.7]
PAS_chr1-4_0095  Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme [KO:K22503] [EC:6.1.1.12]
PAS_chr4_0101  Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA [KO:K01876] [EC:6.1.1.12]
PAS_chr1-1_0390  Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis [KO:K01893] [EC:6.1.1.22]
PAS_chr1-1_0392  Mitochondrial asparaginyl-tRNA synthetase [KO:K01893] [EC:6.1.1.22]
PAS_chr3_0376  Cytoplasmic and mitochondrial glycyl-tRNA synthase [KO:K01880] [EC:6.1.1.14]
PAS_chr2-1_0673  Mitochondrial threonyl-tRNA synthetase [KO:K01868] [EC:6.1.1.3]
PAS_chr2-2_0238  Threonyl-tRNA synthetase, essential cytoplasmic protein [KO:K01868] [EC:6.1.1.3]
PAS_chr1-4_0463  Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase [KO:K01875] [EC:6.1.1.11]
PAS_chr1-4_0104  Probable mitochondrial seryl-tRNA synthetase [KO:K01875] [EC:6.1.1.11]
PAS_chr1-4_0514  hypothetical protein [KO:K01883] [EC:6.1.1.16]
PAS_chr2-1_0396  Mitochondrial methionyl-tRNA synthetase (MetRS) [KO:K01874] [EC:6.1.1.10]
PAS_chr2-1_0346  Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p [KO:K01874] [EC:6.1.1.10]
PAS_chr1-1_0212  Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria [KO:K00604] [EC:2.1.2.9]
PAS_chr3_0754  Mitochondrial and cytoplasmic valyl-tRNA synthetase [KO:K01873] [EC:6.1.1.9]
PAS_chr4_0393  Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA [KO:K01869] [EC:6.1.1.4]
PAS_chr1-4_0534  Mitochondrial leucyl-tRNA synthetase [KO:K01869] [EC:6.1.1.4]
PAS_chr2-1_0123  Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth [KO:K01870] [EC:6.1.1.5]
PAS_chr4_0709  isoleucine-tRNA synthetase [KO:K01870] [EC:6.1.1.5]
PAS_chr3_0949  Lysyl-tRNA synthetase [KO:K04567] [EC:6.1.1.6]
PAS_chr1-1_0047  Mitochondrial lysine-tRNA synthetase [KO:K04567] [EC:6.1.1.6]
PAS_chr3_0166  Arginyl-tRNA synthetase [KO:K01887] [EC:6.1.1.19]
PAS_chr2-2_0209  Protein with similarity to tRNA synthetases [KO:K01881] [EC:6.1.1.15]
PAS_chr1-1_0391  hypothetical protein [KO:K01881] [EC:6.1.1.15]
PAS_chr1-3_0244  Cytoplasmic and mitochondrial histidine tRNA synthetase [KO:K01892] [EC:6.1.1.21]
PAS_chr1-4_0558  Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer [KO:K01889] [EC:6.1.1.20]
PAS_chr4_0276  Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase [KO:K01889] [EC:6.1.1.20]
PAS_chr3_0144  Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate ac [KO:K01890] [EC:6.1.1.20]
PAS_chr4_0522  Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase [KO:K01866] [EC:6.1.1.1]
PAS_chr3_1110  Mitochondrial tyrosyl-tRNA synthetase [KO:K01866] [EC:6.1.1.1]
PAS_chr3_0165  Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA [KO:K01867] [EC:6.1.1.2]
PAS_chr2-2_0245  Mitochondrial tryptophanyl-tRNA synthetase [KO:K01867] [EC:6.1.1.2]
Compound
C00025  L-Glutamate
C00037  Glycine
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00073  L-Methionine
C00078  L-Tryptophan
C00079  L-Phenylalanine
C00082  L-Tyrosine
C00097  L-Cysteine
C00101  Tetrahydrofolate
C00123  L-Leucine
C00135  L-Histidine
C00148  L-Proline
C00152  L-Asparagine
C00183  L-Valine
C00188  L-Threonine
C00234  10-Formyltetrahydrofolate
C00407  L-Isoleucine
C00886  L-Alanyl-tRNA
C01005  O-Phospho-L-serine
C01931  L-Lysyl-tRNA
C02047  L-Leucyl-tRNA
C02163  L-Arginyl-tRNA(Arg)
C02282  Glutaminyl-tRNA
C02412  Glycyl-tRNA(Gly)
C02430  L-Methionyl-tRNA
C02553  L-Seryl-tRNA(Ser)
C02554  L-Valyl-tRNA(Val)
C02702  L-Prolyl-tRNA(Pro)
C02839  L-Tyrosyl-tRNA(Tyr)
C02984  L-Aspartyl-tRNA(Asp)
C02987  L-Glutamyl-tRNA(Glu)
C02988  L-Histidyl-tRNA(His)
C02992  L-Threonyl-tRNA(Thr)
C03125  L-Cysteinyl-tRNA(Cys)
C03127  L-Isoleucyl-tRNA(Ile)
C03294  N-Formylmethionyl-tRNA
C03402  L-Asparaginyl-tRNA(Asn)
C03511  L-Phenylalanyl-tRNA(Phe)
C03512  L-Tryptophanyl-tRNA(Trp)
C06112  L-Glutamyl-tRNA(Gln)
C06113  L-Aspartyl-tRNA(Asn)
C06481  L-Seryl-tRNA(Sec)
C06482  L-Selenocysteinyl-tRNA(Sec)
C16138  L-Pyrrolysine
C16638  O-Phosphoseryl-tRNA(Sec)
C17022  O-Phosphoseryl-tRNA(Cys)
C17027  L-Pyrrolysyl-tRNA(Pyl)
Reference
PMID:18252769
  Authors
Sheppard K, Yuan J, Hohn MJ, Jester B, Devine KM, Soll D
  Title
From one amino acid to another: tRNA-dependent amino acid biosynthesis.
  Journal
Nucleic Acids Res 36:1813-25 (2008)
DOI:10.1093/nar/gkn015
Reference
PMID:15314242
  Authors
Polycarpo C, Ambrogelly A, Berube A, Winbush SM, McCloskey JA, Crain PF, Wood JL, Soll D
  Title
An aminoacyl-tRNA synthetase that specifically activates pyrrolysine.
  Journal
Proc Natl Acad Sci U S A 101:12450-4 (2004)
DOI:10.1073/pnas.0405362101
Related
pathway
ppa00250  Alanine, aspartate and glutamate metabolism
ppa00260  Glycine, serine and threonine metabolism
ppa00270  Cysteine and methionine metabolism
ppa00290  Valine, leucine and isoleucine biosynthesis
ppa00300  Lysine biosynthesis
ppa00330  Arginine and proline metabolism
ppa00340  Histidine metabolism
ppa00380  Tryptophan metabolism
ppa00400  Phenylalanine, tyrosine and tryptophan biosynthesis
KO pathway
ko00970   
LinkDB

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