Entry |
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Symbol |
IARS, ileS
|
Name |
isoleucyl-tRNA synthetase [EC: 6.1.1.5]
|
Pathway |
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Reaction |
R03656 | L-isoleucine:tRNA(Ile) ligase (AMP-forming) |
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Disease |
H02437 | Growth retardation, impaired intellectual development, hypotonia, and hepatopathy |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
09122 Translation
00970 Aminoacyl-tRNA biosynthesis
K01870 IARS, ileS; isoleucyl-tRNA synthetase
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes
K01870 IARS, ileS; isoleucyl-tRNA synthetase
09182 Protein families: genetic information processing
03016 Transfer RNA biogenesis
K01870 IARS, ileS; isoleucyl-tRNA synthetase
Enzymes [BR:ko01000]
6. Ligases
6.1 Forming carbon-oxygen bonds
6.1.1 Ligases forming aminoacyl-tRNA and related compounds
6.1.1.5 isoleucine---tRNA ligase
K01870 IARS, ileS; isoleucyl-tRNA synthetase
Amino acid related enzymes [BR:ko01007]
Aminoacyl-tRNA synthetase
Class I (U)
K01870 IARS, ileS; isoleucyl-tRNA synthetase
Transfer RNA biogenesis [BR:ko03016]
Eukaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Multi-aminoacyl-tRNA synthetase complex (MSC)
K01870 IARS, ileS; isoleucyl-tRNA synthetase
Prokaryotic type
Aminoacyl-tRNA synthetases (AARSs)
Other AARSs
K01870 IARS, ileS; isoleucyl-tRNA synthetase
Aminoacyl-tRNA synthetases [br01613.html]
Aminoacyl-tRNA synthetases in prokaryotes and eukaryotes
K01870
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Shiba K, Suzuki N, Shigesada K, Namba Y, Schimmel P, Noda T |
Title |
Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit. |
Journal |
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Sequence |
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Reference |
|
Authors |
Park SG, Schimmel P, Kim S |
Title |
Aminoacyl tRNA synthetases and their connections to disease. |
Journal |
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Reference |
|
Authors |
Ling J, Reynolds N, Ibba M |
Title |
Aminoacyl-tRNA synthesis and translational quality control. |
Journal |
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LinkDB |
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