KEGG   PATHWAY: ppun00310
Entry
ppun00310                   Pathway                                
Name
Lysine degradation - Pseudomonas putida NBRC 14164
Class
Metabolism; Amino acid metabolism
Pathway map
ppun00310  Lysine degradation
ppun00310

Module
ppun_M00957  Lysine degradation, bacteria, L-lysine => glutarate => succinate/acetyl-CoA [PATH:ppun00310]
ppun_M00960  Lysine degradation, bacteria, L-lysine => D-lysine => succinate [PATH:ppun00310]
Other DBs
GO: 0006554
Organism
Pseudomonas putida NBRC 14164 [GN:ppun]
Gene
PP4_53230  putative aldehyde dehydrogenase [KO:K26061]
PP4_16460  putative 4-aminobutyrate aminotransferase [KO:K26062] [EC:2.6.1.39]
PP4_15700  sucB; 2-oxoglutarate dehydrogenase E2 component [KO:K00658] [EC:2.3.1.61]
PP4_54290  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
PP4_15710  lpd; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
PP4_13570  bkdC; dihydrolipoyl dehydrogenase BkdC [KO:K00382] [EC:1.8.1.4]
PP4_01520  gcdH; glutaryl-CoA dehydrogenase [KO:K00252] [EC:1.3.8.6]
PP4_26090  paaF; 2,3-dehydroadipyl-CoA hydratase PaaF [KO:K01692] [EC:4.2.1.17]
PP4_35980  putative enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
PP4_27160  dcaE; enoyl-CoA hydratase DcaE [KO:K01692] [EC:4.2.1.17]
PP4_37140  fadB; fatty acid oxidation complex subunit alpha [KO:K01825] [EC:1.1.1.35 4.2.1.17 5.1.2.3 5.3.3.8]
PP4_06550  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_35740  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_26800  putative acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_26850  putative acetyl-CoA acyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_20340  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_36000  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_07210  putative acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
PP4_04120  putative tryptophan 2-monooxygenase [KO:K00468] [EC:1.13.12.2]
PP4_04110  putative hydrolase [KO:K01506] [EC:3.5.1.30]
PP4_21000  alr; putative alanine racemase [KO:K25317] [EC:5.1.1.10]
PP4_42310  prr; gamma-aminobutyraldehyde dehydrogenase [KO:K00137] [EC:1.2.1.19]
PP4_02320  putative 5-aminovalerate aminotransferase [KO:K14268] [EC:2.6.1.48 2.6.1.19]
PP4_20680  gabD; succinate-semialdehyde dehydrogenase GabD [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
PP4_02310  putative glutarate-semialdehyde dehydrogenase [KO:K00135] [EC:1.2.1.16 1.2.1.79 1.2.1.20]
PP4_29100  csiD; CsiD protein [KO:K15737] [EC:1.14.11.64]
PP4_29090  putative oxidoreductase [KO:K15736] [EC:1.1.5.13]
PP4_53250  hypothetical protein [KO:K25986] [EC:1.13.11.93]
PP4_13270  putative oxidoreductase [KO:K26063] [EC:1.1.-.-]
PP4_01530  putative CoA-transferase [KO:K01041] [EC:2.8.3.-]
PP4_22310  putative oxidoreductase [KO:K26064]
PP4_22360  putative oxidoreductase [KO:K13609] [EC:1.5.1.21]
PP4_53220  putative oxidoreductase [KO:K26065]
PP4_48050  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
PP4_20800  yfmT; putative aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
PP4_21020  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
Compound
C00024  Acetyl-CoA
C00026  2-Oxoglutarate
C00037  Glycine
C00042  Succinate
C00047  L-Lysine
C00068  Thiamin diphosphate
C00136  Butanoyl-CoA
C00164  Acetoacetate
C00322  2-Oxoadipate
C00332  Acetoacetyl-CoA
C00408  L-Pipecolate
C00431  5-Aminopentanoate
C00449  N6-(L-1,3-Dicarboxypropyl)-L-lysine
C00450  (S)-2,3,4,5-Tetrahydropyridine-2-carboxylate
C00487  Carnitine
C00489  Glutarate
C00527  Glutaryl-CoA
C00739  D-Lysine
C00877  Crotonoyl-CoA
C00956  L-2-Aminoadipate
C00990  5-Aminopentanamide
C01087  (R)-2-Hydroxyglutarate
C01142  (3S)-3,6-Diaminohexanoate
C01144  (S)-3-Hydroxybutanoyl-CoA
C01149  4-Trimethylammoniobutanal
C01181  4-Trimethylammoniobutanoate
C01186  (3S,5S)-3,5-Diaminohexanoate
C01211  Procollagen 5-hydroxy-L-lysine
C01259  (3S)-3-Hydroxy-N6,N6,N6-trimethyl-L-lysine
C01672  Cadaverine
C02188  Protein lysine
C02727  N6-Acetyl-L-lysine
C03087  5-Acetamidopentanoate
C03196  (S)-2-Hydroxyglutarate
C03239  6-Amino-2-oxohexanoate
C03273  5-Oxopentanoate
C03366  5-Phosphooxy-L-lysine
C03656  (S)-5-Amino-3-oxohexanoic acid
C03793  N6,N6,N6-Trimethyl-L-lysine
C04020  D-Lysopine
C04076  L-2-Aminoadipate 6-semialdehyde
C04092  Delta1-Piperideine-2-carboxylate
C04487  5-(D-Galactosyloxy)-L-lysine-procollagen
C05161  (2R,5S)-2,5-Diaminohexanoate
C05231  L-3-Aminobutyryl-CoA
C05544  Protein N6-methyl-L-lysine
C05545  Protein N6,N6-dimethyl-L-lysine
C05546  Protein N6,N6,N6-trimethyl-L-lysine
C05548  6-Acetamido-2-oxohexanoate
C05825  2-Amino-5-oxohexanoate
C06157  [Dihydrolipoyllysine-residue succinyltransferase] S-glutaryldihydrolipoyllysine
C12455  5-Aminopentanal
C15972  Enzyme N6-(lipoyl)lysine
C15973  Enzyme N6-(dihydrolipoyl)lysine
C16741  L-Hydroxylysine
C22667  4-Carboxy-1-hydroxybutyryl-ThPP
Reference
PMID:11802770
  Authors
Vaz FM, Wanders RJ.
  Title
Carnitine biosynthesis in mammals.
  Journal
Biochem J 361:417-29 (2002)
DOI:10.1042/bj3610417
Reference
PMID:1682209
  Authors
Large PJ, Robertson A.
  Title
The route of lysine breakdown in Candida tropicalis.
  Journal
FEMS Microbiol Lett 66:209-13 (1991)
DOI:10.1111/j.1574-6968.1990.tb03998.x
Related
pathway
ppun00020  Citrate cycle (TCA cycle)
ppun00300  Lysine biosynthesis
ppun00780  Biotin metabolism
KO pathway
ko00310   
LinkDB

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