KEGG   PATHWAY: ptol00230
Entry
ptol00230                   Pathway                                
Name
Purine metabolism - Pseudomonas tolaasii
Class
Metabolism; Nucleotide metabolism
Pathway map
ptol00230  Purine metabolism
ptol00230

Module
ptol_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:ptol00230]
ptol_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:ptol00230]
ptol_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:ptol00230]
ptol_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:ptol00230]
ptol_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:ptol00230]
ptol_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:ptol00230]
ptol_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:ptol00230]
Other DBs
GO: 0006163 0042278
Organism
Pseudomonas tolaasii [GN:ptol]
Gene
I7845_02565  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
I7845_01375  nudE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
I7845_15375  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
I7845_28220  phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
I7845_03765  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
I7845_19185  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
I7845_03130  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
I7845_20825  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
I7845_23600  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
I7845_23675  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
I7845_20820  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
I7845_28550  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
I7845_28555  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
I7845_07295  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
I7845_17630  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
I7845_03135  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
I7845_21265  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
I7845_08355  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
I7845_06455  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
I7845_01370  yrfG; GMP/IMP nucleotidase [KO:K20881] [EC:3.1.3.-]
I7845_20345  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
I7845_03670  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
I7845_04020  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
I7845_13235  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
I7845_04640  hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
I7845_23775  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
I7845_23855  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
I7845_27150  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
I7845_28110  xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
I7845_21360  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
I7845_21365  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
I7845_25125  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
I7845_25130  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
I7845_25135  (2Fe-2S)-binding protein [KO:K13483]
I7845_23770  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
I7845_21375  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
I7845_28255  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
I7845_22045  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
I7845_22265  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
I7845_15660  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
I7845_08515  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
I7845_28265  spoT; bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
I7845_27890  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
I7845_20865  relA; GTP diphosphokinase [KO:K00951] [EC:2.7.6.5]
I7845_28005  class I adenylate cyclase [KO:K05851] [EC:4.6.1.1]
I7845_02710  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
I7845_25315  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
I7845_07940  LOG family protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
I7845_03425  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
I7845_06180  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
I7845_20860  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
I7845_02575  cpdA; 3',5'-cyclic-AMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
I7845_16240  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
I7845_26265  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
I7845_21070  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
I7845_03915  cysN; sulfate adenylyltransferase subunit CysN [KO:K00955] [EC:2.7.7.4 2.7.1.25]
I7845_21065  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
I7845_03910  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
I7845_20145  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
I7845_20155  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K13485] [EC:4.1.1.97]
I7845_21630  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
I7845_20150  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
I7845_20160  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
I7845_20165  ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
I7845_02975  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
I7845_02980  urease subunit beta [KO:K01429] [EC:3.5.1.5]
I7845_02995  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
I7845_22910  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
ptol00030  Pentose phosphate pathway
ptol00220  Arginine biosynthesis
ptol00250  Alanine, aspartate and glutamate metabolism
ptol00260  Glycine, serine and threonine metabolism
ptol00340  Histidine metabolism
ptol00630  Glyoxylate and dicarboxylate metabolism
ptol00730  Thiamine metabolism
ptol00740  Riboflavin metabolism
ptol00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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