KEGG   PATHWAY: pvir00480
Entry
pvir00480                   Pathway                                
Name
Glutathione metabolism - Panicum virgatum (switchgrass)
Class
Metabolism; Metabolism of other amino acids
Pathway map
pvir00480  Glutathione metabolism
pvir00480

Module
pvir_M00118  Glutathione biosynthesis, glutamate => glutathione [PATH:pvir00480]
Other DBs
GO: 0006749
Organism
Panicum virgatum (switchgrass) [GN:pvir]
Gene
120642274  glutathione hydrolase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120705974  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120675701  glutathione hydrolase 3-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120683571  glutathione hydrolase 1-like [KO:K18592] [EC:2.3.2.2 3.4.19.13 3.4.19.14]
120641158  gamma-glutamylcyclotransferase 2-3-like [KO:K22596] [EC:4.3.2.9]
120655690  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
120700942  gamma-glutamylcyclotransferase 2-2-like [KO:K22596] [EC:4.3.2.9]
120682803  gamma-glutamylcyclotransferase 2-3-like [KO:K22596] [EC:4.3.2.9]
120690814  5-oxoprolinase-like [KO:K01469] [EC:3.5.2.9]
120651922  5-oxoprolinase-like [KO:K01469] [EC:3.5.2.9]
120674587  glutamate--cysteine ligase B, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120664147  glutamate--cysteine ligase A, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120710535  glutamate--cysteine ligase B, chloroplastic-like [KO:K01919] [EC:6.3.2.2]
120697344  glutamate--cysteine ligase A, chloroplastic [KO:K01919] [EC:6.3.2.2]
120699640  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
120686068  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
120645143  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
120665985  glutathione synthetase, chloroplastic-like isoform X1 [KO:K21456] [EC:6.3.2.3]
120666353  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
120655794  leucine aminopeptidase 2, chloroplastic-like [KO:K01255] [EC:3.4.11.1]
120657474  leucine aminopeptidase 2, chloroplastic [KO:K01255] [EC:3.4.11.1]
120644951  leucine aminopeptidase 2, chloroplastic-like [KO:K01255] [EC:3.4.11.1]
120680171  puromycin-sensitive aminopeptidase-like [KO:K01256] [EC:3.4.11.2]
120713120  puromycin-sensitive aminopeptidase [KO:K01256] [EC:3.4.11.2]
120640662  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120640663  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120655495  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120655550  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120671884  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120671967  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120672216  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120687893  probable glutathione S-transferase GSTU1 isoform X1 [KO:K00799] [EC:2.5.1.18]
120672660  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120672958  glutathione S-transferase 1-like [KO:K00799] [EC:2.5.1.18]
120703696  probable glutathione S-transferase GSTU1 [KO:K00799] [EC:2.5.1.18]
120673456  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120689398  uncharacterized protein LOC120689398 [KO:K00799] [EC:2.5.1.18]
120689556  probable glutathione S-transferase BZ2 [KO:K00799] [EC:2.5.1.18]
120703755  probable glutathione S-transferase GSTU1 isoform X1 [KO:K00799] [EC:2.5.1.18]
120704398  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120659343  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120674024  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120690467  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120674922  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120675385  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120675395  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120675517  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120675574  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120675613  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120690754  glutathione S-transferase T1-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120675757  glutathione S-transferase 4-like [KO:K00799] [EC:2.5.1.18]
120675930  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120676437  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120676447  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120691448  protein IN2-1 homolog B [KO:K00799] [EC:2.5.1.18]
120691736  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120706932  glutathione S-transferase 4-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120706944  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120706946  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120647399  glutathione S-transferase F8, chloroplastic-like [KO:K00799] [EC:2.5.1.18]
120647400  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
120647401  glutathione S-transferase F8, chloroplastic-like [KO:K00799] [EC:2.5.1.18]
120647402  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
120648060  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120648062  uncharacterized protein LOC120648062 [KO:K00799] [EC:2.5.1.18]
120648064  uncharacterized protein LOC120648064 [KO:K00799] [EC:2.5.1.18]
120648066  uncharacterized protein LOC120648066 [KO:K00799] [EC:2.5.1.18]
120661959  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120676725  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120677233  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120692091  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
120692510  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120692707  protein IN2-1 homolog B-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120707147  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120707688  probable glutathione S-transferase GSTU6 isoform X1 [KO:K00799] [EC:2.5.1.18]
120707694  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120648533  probable glutathione S-transferase parA [KO:K00799] [EC:2.5.1.18]
120648999  glutathione S-transferase T1-like [KO:K00799] [EC:2.5.1.18]
120692820  probable glutathione S-transferase GSTU6 isoform X1 [KO:K00799] [EC:2.5.1.18]
120692883  protein IN2-1-like [KO:K00799] [EC:2.5.1.18]
120692945  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120692946  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693096  probable glutathione S-transferase GSTU1 [KO:K00799] [EC:2.5.1.18]
120693170  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693171  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693172  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693319  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693320  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120693373  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
120708147  glutathione S-transferase 1 [KO:K00799] [EC:2.5.1.18]
120649533  probable glutathione S-transferase GSTU1 [KO:K00799] [EC:2.5.1.18]
120649534  probable glutathione S-transferase GSTU1 [KO:K00799] [EC:2.5.1.18]
120650029  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120650030  microsomal glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120679069  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120709171  glutathione S-transferase 3-like [KO:K00799] [EC:2.5.1.18]
120709245  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120709246  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120709248  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120709249  glutathione S-transferase U8-like [KO:K00799] [EC:2.5.1.18]
120709250  probable glutathione S-transferase [KO:K00799] [EC:2.5.1.18]
120709251  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120709527  probable glutathione S-transferase GSTU6 isoform X1 [KO:K00799] [EC:2.5.1.18]
120709788  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120709866  glutathione S-transferase U11-like [KO:K00799] [EC:2.5.1.18]
120665473  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120681699  glutathione transferase GST 23 [KO:K00799] [EC:2.5.1.18]
120710597  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120651812  glutathione S-transferase F11-like [KO:K00799] [EC:2.5.1.18]
120651882  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120651886  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120651887  probable glutathione S-transferase GSTU6 isoform X1 [KO:K00799] [EC:2.5.1.18]
120651888  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120651890  glutathione S-transferase U18-like [KO:K00799] [EC:2.5.1.18]
120651891  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120651892  glutathione S-transferase U17-like [KO:K00799] [EC:2.5.1.18]
120651893  probable glutathione S-transferase GSTU6 [KO:K00799] [EC:2.5.1.18]
120697431  glutathione S-transferase 4-like [KO:K00799] [EC:2.5.1.18]
120697435  glutathione S-transferase 4-like [KO:K00799] [EC:2.5.1.18]
120697437  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120652764  protein IN2-1 [KO:K00799] [EC:2.5.1.18]
120652765  protein IN2-1 homolog B-like [KO:K00799] [EC:2.5.1.18]
120652766  protein IN2-1 homolog B-like isoform X1 [KO:K00799] [EC:2.5.1.18]
120667200  glutathione S-transferase 4-like [KO:K00799] [EC:2.5.1.18]
120667203  probable glutathione S-transferase GSTF1 [KO:K00799] [EC:2.5.1.18]
120668702  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120698688  glutathione transferase GST 23-like [KO:K00799] [EC:2.5.1.18]
120670112  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120703055  probable glutathione S-transferase DHAR2, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120664052  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120697269  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120667827  probable glutathione S-transferase DHAR1, cytosolic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
120657577  glutathione reductase, cytosolic-like isoform X1 [KO:K00383] [EC:1.8.1.7]
120689761  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120646031  glutathione reductase, cytosolic [KO:K00383] [EC:1.8.1.7]
120647217  glutathione reductase, chloroplastic-like [KO:K00383] [EC:1.8.1.7]
120642438  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120672888  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120664571  isocitrate dehydrogenase [NADP] [KO:K00031] [EC:1.1.1.42]
120710029  cytosolic isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120681318  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120681850  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120697781  isocitrate dehydrogenase [NADP]-like [KO:K00031] [EC:1.1.1.42]
120671054  6-phosphogluconate dehydrogenase, decarboxylating 1-like isoform X1 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120702378  6-phosphogluconate dehydrogenase, decarboxylating 1-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120672376  6-phosphogluconate dehydrogenase, decarboxylating 1 [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120644353  6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120709194  6-phosphogluconate dehydrogenase, decarboxylating 1-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120684602  6-phosphogluconate dehydrogenase, decarboxylating 2, chloroplastic-like [KO:K00033] [EC:1.1.1.44 1.1.1.343]
120641302  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120656332  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120673093  glucose-6-phosphate 1-dehydrogenase 2, chloroplastic-like isoform X1 [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120690966  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like isoform X1 [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120692589  inactive glucose-6-phosphate 1-dehydrogenase 4, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120707478  glucose-6-phosphate 1-dehydrogenase 2, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120707485  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120680731  glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120652070  glucose-6-phosphate 1-dehydrogenase, chloroplastic-like isoform X1 [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120652564  inactive glucose-6-phosphate 1-dehydrogenase 4, chloroplastic-like [KO:K00036] [EC:1.1.1.49 1.1.1.363]
120686136  probable glutathione peroxidase 2 [KO:K00432] [EC:1.11.1.9]
120656726  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120687881  probable glutathione peroxidase 4 [KO:K00432] [EC:1.11.1.9]
120642741  probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial [KO:K00432] [EC:1.11.1.9]
120691090  probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial [KO:K00432] [EC:1.11.1.9]
120681628  probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial [KO:K00432] [EC:1.11.1.9]
120652303  probable glutathione peroxidase 4 [KO:K00432] [EC:1.11.1.9]
120711849  probable phospholipid hydroperoxide glutathione peroxidase [KO:K00432] [EC:1.11.1.9]
120652424  probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial [KO:K00432] [EC:1.11.1.9]
120661970  1-Cys peroxiredoxin PER1-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
120696243  1-Cys peroxiredoxin PER1-like [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
120658223  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
120696143  ornithine decarboxylase-like [KO:K01581] [EC:4.1.1.17]
120655281  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120670108  spermine synthase-like isoform X1 [KO:K00797] [EC:2.5.1.16]
120658119  spermidine synthase 1-like [KO:K00797] [EC:2.5.1.16]
120704749  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120696718  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
120669165  spermidine synthase 1 isoform X1 [KO:K00797] [EC:2.5.1.16]
120640175  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
120640948  probable L-ascorbate peroxidase 8, chloroplastic isoform X1 [KO:K00434] [EC:1.11.1.11]
120641028  probable L-ascorbate peroxidase 7, chloroplastic [KO:K00434] [EC:1.11.1.11]
120687989  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
120662269  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
120663742  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
120678459  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
120678528  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
120696865  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
120682240  probable L-ascorbate peroxidase 8, chloroplastic [KO:K00434] [EC:1.11.1.11]
120682370  probable L-ascorbate peroxidase 7, chloroplastic [KO:K00434] [EC:1.11.1.11]
120652750  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
120712855  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
120683430  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
120713778  probable L-ascorbate peroxidase 4, peroxisomal [KO:K00434] [EC:1.11.1.11]
120669958  ribonucleoside-diphosphate reductase large subunit isoform X1 [KO:K10807] [EC:1.17.4.1]
120702745  ribonucleoside-diphosphate reductase large subunit-like [KO:K10807] [EC:1.17.4.1]
120657530  ribonucleoside-diphosphate reductase large subunit-like isoform X1 [KO:K10807] [EC:1.17.4.1]
120645405  ribonucleoside-diphosphate reductase large subunit-like isoform X1 [KO:K10807] [EC:1.17.4.1]
120669041  LOW QUALITY PROTEIN: uncharacterized protein LOC120669041 [KO:K10807] [EC:1.17.4.1]
120670568  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120642514  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120704674  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120651599  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120697028  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
120683113  ribonucleoside-diphosphate reductase small chain-like [KO:K10808] [EC:1.17.4.1]
Compound
C00005  NADPH
C00006  NADP+
C00024  Acetyl-CoA
C00025  L-Glutamate
C00037  Glycine
C00051  Glutathione
C00072  Ascorbate
C00077  L-Ornithine
C00097  L-Cysteine
C00127  Glutathione disulfide
C00134  Putrescine
C00151  L-Amino acid
C00315  Spermidine
C00669  gamma-L-Glutamyl-L-cysteine
C00750  Spermine
C01322  RX
C01419  Cys-Gly
C01672  Cadaverine
C01879  5-Oxoproline
C02090  Trypanothione
C02320  R-S-Glutathione
C03170  Trypanothione disulfide
C03646  Bis-gamma-glutamylcystine
C03740  (5-L-Glutamyl)-L-amino acid
C05422  Dehydroascorbate
C05726  S-Substituted L-cysteine
C05727  S-Substituted N-acetyl-L-cysteine
C05729  R-S-Cysteinylglycine
C05730  Glutathionylspermidine
C16562  Glutathionylspermine
C16563  Bis(glutathionyl)spermine
C16564  Bis(glutathionyl)spermine disulfide
C16565  Aminopropylcadaverine
C16566  Glutathionylaminopropylcadaverine
C16567  Homotrypanothione
C16568  Homotrypanothione disulfide
C16663  Tryparedoxin
C16664  Tryparedoxin disulfide
Reference
PMID:12675513
  Authors
Josch C, Klotz LO, Sies H.
  Title
Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver.
  Journal
Biol Chem 384:213-8 (2003)
DOI:10.1515/BC.2003.023
Reference
PMID:18482986
  Authors
Chu L, Lai Y, Xu X, Eddy S, Yang S, Song L, Kolodrubetz D.
  Title
A 52-kDa leucyl aminopeptidase from treponema denticola is a cysteinylglycinase that mediates the second step of glutathione metabolism.
  Journal
J Biol Chem 283:19351-8 (2008)
DOI:10.1074/jbc.M801034200
Reference
PMID:14583094
  Authors
Cappiello M, Lazzarotti A, Buono F, Scaloni A, D'Ambrosio C, Amodeo P, Mendez BL, Pelosi P, Del Corso A, Mura U.
  Title
New role for leucyl aminopeptidase in glutathione turnover.
  Journal
Biochem J 378:35-44 (2004)
DOI:10.1042/BJ20031336
Reference
PMID:11157967
  Authors
Suzuki H, Kamatani S, Kim ES, Kumagai H.
  Title
Aminopeptidases A, B, and N and dipeptidase D are the four cysteinylglycinases of Escherichia coli K-12.
  Journal
J Bacteriol 183:1489-90 (2001)
DOI:10.1128/JB.183.4.1489-1490.2001
Reference
PMID:15610825
  Authors
Oza SL, Shaw MP, Wyllie S, Fairlamb AH.
  Title
Trypanothione biosynthesis in Leishmania major.
  Journal
Mol Biochem Parasitol 139:107-16 (2005)
DOI:10.1016/j.molbiopara.2004.10.004
Reference
PMID:12049631
  Authors
Oza SL, Ariyanayagam MR, Fairlamb AH.
  Title
Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.
  Journal
Biochem J 364:679-86 (2002)
DOI:10.1042/BJ20011370
Reference
PMID:9677355
  Authors
Tetaud E, Manai F, Barrett MP, Nadeau K, Walsh CT, Fairlamb AH.
  Title
Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.
  Journal
J Biol Chem 273:19383-90 (1998)
DOI:10.1074/jbc.273.31.19383
Reference
PMID:12750367
  Authors
Ariyanayagam MR, Oza SL, Mehlert A, Fairlamb AH.
  Title
Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi.
  Journal
J Biol Chem 278:27612-9 (2003)
DOI:10.1074/jbc.M302750200
Reference
PMID:12967709
  Authors
Oza SL, Ariyanayagam MR, Aitcheson N, Fairlamb AH.
  Title
Properties of trypanothione synthetase from Trypanosoma brucei.
  Journal
Mol Biochem Parasitol 131:25-33 (2003)
DOI:10.1016/S0166-6851(03)00176-2
Reference
PMID:12121990
  Authors
Oza SL, Tetaud E, Ariyanayagam MR, Warnon SS, Fairlamb AH.
  Title
A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi.
  Journal
J Biol Chem 277:35853-61 (2002)
DOI:10.1074/jbc.M204403200
Reference
PMID:15537651
  Authors
Comini M, Menge U, Wissing J, Flohe L.
  Title
Trypanothione synthesis in crithidia revisited.
  Journal
J Biol Chem 280:6850-60 (2005)
DOI:10.1074/jbc.M404486200
Reference
PMID:7813456
  Authors
Hunter KJ, Le Quesne SA, Fairlamb AH.
  Title
Identification and biosynthesis of N1,N9-bis(glutathionyl)aminopropylcadaverine (homotrypanothione) in Trypanosoma cruzi.
  Journal
Eur J Biochem 226:1019-27 (1994)
DOI:10.1111/j.1432-1033.1994.t01-1-01019.x
Reference
PMID:12751784
  Authors
Krauth-Siegel RL, Meiering SK, Schmidt H.
  Title
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
  Journal
Biol Chem 384:539-49 (2003)
DOI:10.1515/BC.2003.062
Reference
PMID:18395526
  Authors
Krauth-Siegel RL, Comini MA.
  Title
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism.
  Journal
Biochim Biophys Acta 1780:1236-48 (2008)
DOI:10.1016/j.bbagen.2008.03.006
Reference
PMID:8892297
  Authors
Krauth-Siegel RL, Ludemann H.
  Title
Reduction of dehydroascorbate by trypanothione.
  Journal
Mol Biochem Parasitol 80:203-8 (1996)
DOI:10.1016/0166-6851(96)02689-8
Reference
PMID:11150302
  Authors
Dormeyer M, Reckenfelderbaumer N, Ludemann H, Krauth-Siegel RL.
  Title
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
  Journal
J Biol Chem 276:10602-6 (2001)
DOI:10.1074/jbc.M010352200
Reference
PMID:12949079
  Authors
Schmidt H, Krauth-Siegel RL.
  Title
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei.
  Journal
J Biol Chem 278:46329-36 (2003)
DOI:10.1074/jbc.M305338200
Reference
PMID:9851611
  Authors
Tetaud E, Fairlamb AH.
  Title
Cloning, expression and reconstitution of the trypanothione-dependent peroxidase system of Crithidia fasciculata.
  Journal
Mol Biochem Parasitol 96:111-23 (1998)
DOI:10.1016/S0166-6851(98)00120-0
Reference
PMID:12446213
  Authors
Castro H, Sousa C, Santos M, Cordeiro-da-Silva A, Flohe L, Tomas AM.
  Title
Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum.
  Journal
Free Radic Biol Med 33:1552-62 (2002)
DOI:10.1016/S0891-5849(02)01089-4
Reference
PMID:10713147
  Authors
Wilkinson SR, Temperton NJ, Mondragon A, Kelly JM.
  Title
Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi.
  Journal
J Biol Chem 275:8220-5 (2000)
DOI:10.1074/jbc.275.11.8220
Reference
PMID:17922848
  Authors
Konig J, Fairlamb AH.
  Title
A comparative study of type I and type II tryparedoxin peroxidases in Leishmania major.
  Journal
FEBS J 274:5643-58 (2007)
DOI:10.1111/j.1742-4658.2007.06087.x
Reference
PMID:12466271
  Authors
Hillebrand H, Schmidt A, Krauth-Siegel RL.
  Title
A second class of peroxidases linked to the trypanothione metabolism.
  Journal
J Biol Chem 278:6809-15 (2003)
DOI:10.1074/jbc.M210392200
Reference
PMID:14982633
  Authors
Soksawatmaekhin W, Kuraishi A, Sakata K, Kashiwagi K, Igarashi K.
  Title
Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli.
  Journal
Mol Microbiol 51:1401-12 (2004)
DOI:10.1046/j.1365-2958.2003.03913.x
Reference
PMID:6798961
  Authors
Pegg AE, Shuttleworth K, Hibasami H.
  Title
Specificity of mammalian spermidine synthase and spermine synthase.
  Journal
Biochem J 197:315-20 (1981)
DOI:10.1042/bj1970315
Related
pathway
pvir00220  Arginine biosynthesis
pvir00250  Alanine, aspartate and glutamate metabolism
pvir00270  Cysteine and methionine metabolism
pvir00430  Taurine and hypotaurine metabolism
pvir00460  Cyanoamino acid metabolism
KO pathway
ko00480   
LinkDB

DBGET integrated database retrieval system