KEGG   PATHWAY: pxb04141
Entry
pxb04141                    Pathway                                
Name
Protein processing in endoplasmic reticulum - Pyrus x bretschneideri (Chinese white pear)
Description
The endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylated. Correctly folded proteins are packaged into transport vesicles that shuttle them to the Golgi complex. Misfolded proteins are retained within the ER lumen in complex with molecular chaperones. Proteins that are terminally misfolded bind to BiP and are directed toward degradation through the proteasome in a process called ER-associated degradation (ERAD). Accumulation of misfolded proteins in the ER causes ER stress and activates a signaling pathway called the unfolded protein response (UPR). In certain severe situations, however, the protective mechanisms activated by the UPR are not sufficient to restore normal ER function and cells die by apoptosis.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
pxb04141  Protein processing in endoplasmic reticulum
pxb04141

Other DBs
GO: 0030433 0034976
Organism
Pyrus x bretschneideri (Chinese white pear) [GN:pxb]
Gene
103926870  protein transport protein Sec61 subunit alpha-like [KO:K10956]
103944055  protein transport protein Sec61 subunit alpha-like [KO:K10956]
103934872  protein transport protein Sec61 subunit alpha-like [KO:K10956]
103927827  protein transport protein Sec61 subunit beta-like [KO:K09481]
103930622  protein transport protein Sec61 subunit beta [KO:K09481]
103935143  protein transport protein Sec61 subunit beta-like [KO:K09481]
103957358  protein transport protein Sec61 subunit beta-like [KO:K09481]
103936028  protein transport protein Sec61 subunit gamma [KO:K07342]
103962478  protein transport protein Sec61 subunit gamma [KO:K07342]
103967438  protein transport protein Sec61 subunit gamma [KO:K07342]
103935641  uncharacterized protein LOC103935641 [KO:K12275]
103955929  uncharacterized protein LOC103955929 [KO:K12275]
103963814  uncharacterized protein LOC103963814 [KO:K12275]
103958205  dnaJ protein ERDJ2A-like [KO:K09540]
103964339  dnaJ protein ERDJ2A-like [KO:K09540]
103966149  dnaJ protein ERDJ2A-like [KO:K09540]
103966164  dnaJ protein ERDJ2A-like [KO:K09540]
103936646  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1B [KO:K12666]
103952914  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A-like [KO:K12666]
103961750  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1A-like [KO:K12666]
103928776  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2-like isoform X1 [KO:K12667]
103942735  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2-like [KO:K12667]
103958868  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2-like isoform X1 [KO:K12667]
103956543  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 [KO:K12668]
103940190  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [KO:K12670]
103934696  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [KO:K12670]
103964412  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [KO:K12670]
103963172  dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit-like [KO:K12670]
103946853  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B [KO:K07151] [EC:2.4.99.18]
103943889  dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [KO:K07151] [EC:2.4.99.18]
103933016  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B isoform X1 [KO:K19478]
103948137  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B isoform X1 [KO:K19478]
103954729  probable dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B [KO:K19478]
103950474  oligosaccharyltransferase complex subunit ostc-like [KO:K26501]
103951860  transmembrane protein 258 [KO:K26502]
103943995  transmembrane protein 258 [KO:K26502]
103961481  mannosyl-oligosaccharide glucosidase GCS1-like [KO:K01228] [EC:3.2.1.106]
103961483  mannosyl-oligosaccharide glucosidase GCS1-like isoform X1 [KO:K01228] [EC:3.2.1.106]
103964162  heat shock 70 kDa protein 17-like [KO:K09486]
103966513  heat shock 70 kDa protein 17-like [KO:K09486]
103949272  luminal-binding protein 5-like [KO:K09490] [EC:3.6.4.10]
103935935  luminal-binding protein 5 [KO:K09490] [EC:3.6.4.10]
103965366  LOW QUALITY PROTEIN: mediator of RNA polymerase II transcription subunit 37f [KO:K09490] [EC:3.6.4.10]
103931985  dnaJ protein ERDJ3B [KO:K09517]
103967157  dnaJ protein ERDJ3B-like [KO:K09517]
103934722  dnaJ protein P58IPK homolog [KO:K09523]
103966030  dnaJ protein P58IPK homolog [KO:K09523]
103927703  endoplasmin homolog [KO:K09487]
103946600  heat shock protein 90-5, chloroplastic [KO:K09487]
103955091  heat shock protein 90-6, mitochondrial [KO:K09487]
103946785  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
103954100  probable glucan 1,3-alpha-glucosidase [KO:K05546] [EC:3.2.1.207]
103931450  glucosidase 2 subunit beta-like isoform X1 [KO:K08288]
103964887  glucosidase 2 subunit beta-like [KO:K08288]
103950371  calnexin homolog 1-like [KO:K08054]
103950765  calnexin homolog [KO:K08054]
103950778  calnexin homolog [KO:K08054]
103944738  calnexin homolog 1-like [KO:K08054]
103962652  calnexin homolog isoform X1 [KO:K08054]
103930566  calreticulin-like [KO:K08057]
103951844  calreticulin-3-like [KO:K08057]
103932480  calreticulin-3-like [KO:K08057]
103932466  calreticulin-3-like [KO:K08057]
103933225  calreticulin-3 [KO:K08057]
103962308  calreticulin [KO:K08057]
103939709  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like isoform X1 [KO:K01230] [EC:3.2.1.113]
103932616  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like [KO:K01230] [EC:3.2.1.113]
103926814  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like [KO:K01230] [EC:3.2.1.113]
103937765  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS1-like [KO:K01230] [EC:3.2.1.113]
103951272  mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS3 [KO:K23741] [EC:3.2.1.209]
103943012  SEC12-like protein 2 isoform X1 [KO:K14003]
103951698  SEC12-like protein 1 [KO:K14003]
103931869  SEC12-like protein 2 isoform X1 [KO:K14003]
103962807  SEC12-like protein 1 [KO:K14003]
103962777  SEC12-like protein 1 [KO:K14003]
103941731  small COPII coat GTPase SAR1-like [KO:K07953] [EC:3.6.5.-]
103930569  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
103940494  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
103940495  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103932006  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103962305  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
103959322  GTP-binding protein SAR1A-like [KO:K07953] [EC:3.6.5.-]
103959323  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103967165  GTP-binding protein SAR1A [KO:K07953] [EC:3.6.5.-]
103928462  protein transport protein SEC13 homolog B [KO:K14004]
103944828  protein transport protein SEC13 homolog B-like [KO:K14004]
103966624  protein transport protein SEC13 homolog B-like [KO:K14004]
103942791  protein SEC13 homolog [KO:K14004]
103945535  protein transport protein SEC31 homolog B-like isoform X1 [KO:K14005]
103957619  protein transport protein SEC31 homolog B-like [KO:K14005]
103940580  protein transport protein SEC23-like [KO:K14006]
103951649  protein transport protein SEC23-like [KO:K14006]
103928339  protein transport protein SEC23-like [KO:K14006]
103962901  protein transport protein SEC23-like isoform X1 [KO:K14006]
103965016  protein transport protein SEC23-like [KO:K14006]
103962593  protein transport protein SEC23-like [KO:K14006]
103966693  protein transport protein SEC23-like [KO:K14006]
103942629  protein transport protein Sec24C-like [KO:K14007]
103952220  protein transport protein Sec24-like At4g32640 [KO:K14007]
103943144  protein transport protein Sec24-like At4g32640 [KO:K14007]
103928241  protein transport protein Sec24-like At3g07100 [KO:K14007]
103955325  protein transport protein Sec24-like At3g07100 [KO:K14007]
103955329  protein transport protein Sec24-like At4g32640 [KO:K14007]
103966045  protein transport protein Sec24-like At4g32640 [KO:K14007]
103956602  protein transport protein Sec24-like At4g32640 isoform X1 [KO:K14007]
103955866  protein transport protein Sec24-like At3g07100 [KO:K14007]
103940000  UDP-glucose:glycoprotein glucosyltransferase-like [KO:K11718] [EC:2.4.1.-]
103946309  UDP-glucose:glycoprotein glucosyltransferase-like [KO:K11718] [EC:2.4.1.-]
103927850  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
103942621  protein disulfide-isomerase-like [KO:K09580] [EC:5.3.4.1]
103952581  protein disulfide-isomerase 5-2-like [KO:K09580] [EC:5.3.4.1]
103937287  protein disulfide-isomerase-like [KO:K09580] [EC:5.3.4.1]
103930424  protein disulfide isomerase-like 1-6 [KO:K09580] [EC:5.3.4.1]
103930453  protein disulfide isomerase-like 1-6 [KO:K09580] [EC:5.3.4.1]
103967953  protein disulfide-isomerase 5-2-like [KO:K09580] [EC:5.3.4.1]
103956775  protein disulfide isomerase-like 1-4 [KO:K09580] [EC:5.3.4.1]
103930571  probable protein disulfide-isomerase A6 [KO:K09584] [EC:5.3.4.1]
103942850  protein disulfide-isomerase erp38-like [KO:K09584] [EC:5.3.4.1]
103955002  protein disulfide isomerase-like 2-3 [KO:K09584] [EC:5.3.4.1]
103962302  probable protein disulfide-isomerase A6 [KO:K09584] [EC:5.3.4.1]
103951303  endoplasmic reticulum oxidoreductin-1-like isoform X2 [KO:K10950] [EC:1.8.4.-]
103930746  protein OS-9 homolog [KO:K10088]
103949161  protein OS-9 homolog [KO:K10088]
103953853  protein OS-9 homolog [KO:K10088]
103966226  translocon-associated protein subunit alpha-like [KO:K13249]
103966227  translocon-associated protein subunit alpha-like [KO:K13249]
103966228  translocon-associated protein subunit alpha-like [KO:K13249]
103966229  translocon-associated protein subunit alpha-like isoform X1 [KO:K13249]
103936092  translocon-associated protein subunit beta-like [KO:K13250]
103966569  translocon-associated protein subunit beta-like [KO:K13250]
103951454  uncharacterized protein LOC103951454 [KO:K14009]
103949437  B-cell receptor-associated protein 31-like [KO:K14009]
103948199  uncharacterized protein LOC103948199 [KO:K14009]
103944549  B-cell receptor-associated protein 31-like [KO:K14009]
103938808  B-cell receptor-associated protein 31-like [KO:K14009]
103927689  B-cell receptor-associated protein 31-like [KO:K14009]
103961070  B-cell receptor-associated protein 31 [KO:K14009]
103960012  B-cell receptor-associated protein 31-like [KO:K14009]
103937325  derlin-2.2 [KO:K13989]
103948154  derlin-2.2 [KO:K13989]
103953232  derlin-2.2 [KO:K13989]
103943923  derlin-1 [KO:K13989]
103961923  derlin-1.1-like [KO:K13989]
103959798  derlin-1.1-like [KO:K13989]
103929929  plant UBX domain-containing protein 11-like isoform X2 [KO:K24348]
103963468  UBX domain-containing protein 4 [KO:K24348]
103955246  UBX domain-containing protein 4-like [KO:K24348]
103953623  plant UBX domain-containing protein 11-like [KO:K24348]
103943065  plant UBX domain-containing protein 2 [KO:K14011]
103948217  plant UBX domain-containing protein 4-like [KO:K14012]
103947355  plant UBX domain-containing protein 4 [KO:K14012]
103954967  plant UBX domain-containing protein 4 [KO:K14012]
103947695  cell division cycle protein 48 homolog [KO:K13525]
103927454  cell division control protein 48 homolog D [KO:K13525]
103965472  cell division control protein 48 homolog D-like [KO:K13525]
103964823  cell division cycle protein 48 homolog [KO:K13525]
103952984  cell division cycle protein 48 homolog [KO:K13525]
103938783  NPL4-like protein 2 [KO:K14015]
103937083  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
103943908  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
103954283  ubiquitin fusion degradation protein 1 homolog isoform X1 [KO:K14016]
103966942  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
103964680  ubiquitin fusion degradation protein 1 homolog [KO:K14016]
103945002  heat shock 70 kDa protein 6, chloroplastic-like [KO:K03283]
103929472  heat shock cognate 70 kDa protein-like isoform X1 [KO:K03283]
103931072  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103945383  heat shock 70 kDa protein-like [KO:K03283]
103945384  heat shock 70 kDa protein-like [KO:K03283]
103946362  stromal 70 kDa heat shock-related protein, chloroplastic-like [KO:K03283]
103949050  heat shock 70 kDa protein-like [KO:K03283]
103935268  heat shock cognate 70 kDa protein-like [KO:K03283]
103935280  heat shock cognate 70 kDa protein-like [KO:K03283]
103935290  heat shock cognate 70 kDa protein-like [KO:K03283]
103935315  heat shock cognate 70 kDa protein-like [KO:K03283]
103935325  heat shock cognate 70 kDa protein-like [KO:K03283]
103948411  heat shock cognate 70 kDa protein 2 [KO:K03283]
103948414  heat shock cognate 70 kDa protein-like [KO:K03283]
103944940  heat shock cognate 70 kDa protein 2-like [KO:K03283]
103945001  stromal 70 kDa heat shock-related protein, chloroplastic [KO:K03283]
103956001  heat shock 70 kDa protein [KO:K03283]
103956439  heat shock cognate 70 kDa protein-like isoform X1 [KO:K03283]
103956440  heat shock cognate 70 kDa protein-like isoform X1 [KO:K03283]
103956441  heat shock 70 kDa protein 18-like [KO:K03283]
103966404  heat shock 70 kDa protein 18-like [KO:K03283]
103963573  probable mediator of RNA polymerase II transcription subunit 37e [KO:K03283]
103963598  heat shock cognate 70 kDa protein-like [KO:K03283]
103933608  dnaJ protein homolog [KO:K09503]
103928995  dnaJ protein homolog [KO:K09503]
103957942  dnaJ protein homolog [KO:K09503]
103943664  chaperone protein dnaJ 49 [KO:K09518]
103958303  chaperone protein dnaJ 49-like [KO:K09518]
103952262  heat shock protein 90-2 [KO:K04079]
103956927  heat shock protein 90-2 [KO:K04079]
103964327  heat shock protein 83-like [KO:K04079]
103958215  heat shock protein 83 [KO:K04079]
103966141  heat shock protein 83-like [KO:K04079]
103966169  heat shock protein 83-like [KO:K04079]
103930915  hsp70 nucleotide exchange factor fes1-like [KO:K09562]
103930933  hsp70 nucleotide exchange factor fes1 [KO:K09562]
103944727  hsp70 nucleotide exchange factor FES1 [KO:K09562]
103948590  17.4 kDa class III heat shock protein-like [KO:K13993]
103949874  small heat shock protein, chloroplastic-like [KO:K13993]
103953301  18.1 kDa class I heat shock protein-like [KO:K13993]
103953325  15.4 kDa class V heat shock protein-like [KO:K13993]
103927498  17.1 kDa class II heat shock protein-like [KO:K13993]
103927499  17.1 kDa class II heat shock protein-like [KO:K13993]
103927502  17.1 kDa class II heat shock protein-like [KO:K13993]
103927503  17.1 kDa class II heat shock protein-like [KO:K13993]
103927504  17.9 kDa class II heat shock protein-like [KO:K13993]
103948601  17.4 kDa class III heat shock protein-like [KO:K13993]
103940225  small heat shock protein, chloroplastic [KO:K13993]
103936191  16.9 kDa class I heat shock protein 2-like [KO:K13993]
103936199  18.1 kDa class I heat shock protein-like [KO:K13993]
103936226  18.5 kDa class I heat shock protein-like [KO:K13993]
103937326  15.4 kDa class V heat shock protein-like [KO:K13993]
103951596  small heat shock protein, chloroplastic-like [KO:K13993]
103943366  small heat shock protein, chloroplastic-like [KO:K13993]
103948158  15.4 kDa class V heat shock protein [KO:K13993]
103942692  16.9 kDa class I heat shock protein 2-like [KO:K13993]
103942700  18.2 kDa class I heat shock protein-like isoform X1 [KO:K13993]
103942709  16.9 kDa class I heat shock protein 2-like [KO:K13993]
103952522  17.1 kDa class II heat shock protein-like [KO:K13993]
103936175  18.1 kDa class I heat shock protein-like [KO:K13993]
103936185  18.1 kDa class I heat shock protein-like [KO:K13993]
103946415  16.9 kDa class I heat shock protein 1-like [KO:K13993]
103932695  heat shock 22 kDa protein, mitochondrial-like [KO:K13993]
103955267  26.5 kDa heat shock protein, mitochondrial [KO:K13993]
103959824  23.6 kDa heat shock protein, mitochondrial-like [KO:K13993]
103958131  17.6 kDa class I heat shock protein-like [KO:K13993]
103959948  LOW QUALITY PROTEIN: 15.7 kDa heat shock protein, peroxisomal [KO:K13993]
103960954  class I heat shock protein-like [KO:K13993]
103963260  17.6 kDa class I heat shock protein [KO:K13993]
103960307  22.0 kDa class IV heat shock protein [KO:K13993]
103963453  heat shock 22 kDa protein, mitochondrial-like [KO:K13993]
103961953  23.6 kDa heat shock protein, mitochondrial-like [KO:K13993]
103955448  17.1 kDa class II heat shock protein-like [KO:K13993]
103959434  15.7 kDa heat shock protein, peroxisomal-like [KO:K13993]
103959693  class I heat shock protein-like [KO:K13993]
103940610  ubiquitin thioesterase OTU1-like isoform X1 [KO:K13719] [EC:3.1.2.-]
103951354  ubiquitin thioesterase OTU1-like [KO:K13719] [EC:3.1.2.-]
103961813  ubiquitin thioesterase OTU1-like [KO:K13719] [EC:3.1.2.-]
103947490  ubiquitin receptor RAD23c-like [KO:K10839]
103947820  ubiquitin receptor RAD23d [KO:K10839]
103945402  ubiquitin receptor RAD23b-like [KO:K10839]
103947149  ubiquitin receptor RAD23d-like [KO:K10839]
103955100  ubiquitin receptor RAD23b-like isoform X1 [KO:K10839]
103960249  ubiquitin receptor RAD23b [KO:K10839]
103937699  ubiquitin domain-containing protein DSK2a-like [KO:K04523]
103929613  ubiquitin domain-containing protein DSK2b-like isoform X1 [KO:K04523]
103962424  ubiquitin domain-containing protein DSK2a-like [KO:K04523]
103954417  peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase [KO:K01456] [EC:3.5.1.52]
103949440  ataxin-3 homolog isoform X1 [KO:K11863] [EC:3.4.22.-]
103959594  ataxin-3 homolog isoform X1 [KO:K11863] [EC:3.4.22.-]
103951013  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
103955772  probable ubiquitin conjugation factor E4 [KO:K10597] [EC:2.3.2.27]
103937127  eukaryotic translation initiation factor 2 subunit alpha-like [KO:K03237]
103958644  eukaryotic translation initiation factor 2 subunit alpha [KO:K03237]
103962970  subtilisin-like protease SBT6.1 isoform X1 [KO:K08653] [EC:3.4.21.112]
103958088  membrane-bound transcription factor site-2 protease homolog isoform X1 [KO:K07765] [EC:3.4.24.85]
103961737  serine/threonine-protein kinase/endoribonuclease IRE1b isoform X1 [KO:K08852] [EC:2.7.11.1 3.1.26.-]
103959164  LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE1a-like [KO:K08852] [EC:2.7.11.1 3.1.26.-]
103959313  ubiquitin-conjugating enzyme E2 32 [KO:K10578] [EC:2.3.2.23]
103944946  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
103948981  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
103930042  ubiquitin-conjugating enzyme E2 7 [KO:K10575] [EC:2.3.2.23]
103948405  ubiquitin-conjugating enzyme E2 7-like [KO:K10575] [EC:2.3.2.23]
103943302  ERAD-associated E3 ubiquitin-protein ligase HRD1B-like [KO:K10601] [EC:2.3.2.27]
103951511  ERAD-associated E3 ubiquitin-protein ligase HRD1B-like isoform X2 [KO:K10601] [EC:2.3.2.27]
103947622  E3 ubiquitin-protein ligase RMA1H1-like isoform X1 [KO:K10666] [EC:2.3.2.27]
103958851  RING finger protein 219 [KO:K10666] [EC:2.3.2.27]
103934602  E3 ubiquitin-protein ligase RMA1H1-like isoform X1 [KO:K10666] [EC:2.3.2.27]
103948527  E3 ubiquitin-protein ligase RMA1H1-like [KO:K10666] [EC:2.3.2.27]
103954244  E3 ubiquitin-protein ligase RNF185-like [KO:K10666] [EC:2.3.2.27]
103955443  E3 ubiquitin-protein ligase RNF185 isoform X1 [KO:K10666] [EC:2.3.2.27]
103963165  E3 ubiquitin-protein ligase RNF185-like [KO:K10666] [EC:2.3.2.27]
103931103  E3 ubiquitin-protein ligase RMA1H1-like [KO:K10666] [EC:2.3.2.27]
103944218  E3 ubiquitin-protein ligase RMA1H1-like [KO:K10666] [EC:2.3.2.27]
103950570  ERAD-associated E3 ubiquitin-protein ligase component HRD3A [KO:K14026]
103946929  ERAD-associated E3 ubiquitin-protein ligase component HRD3A-like [KO:K14026]
103932670  E3 ubiquitin protein ligase RIN2-like isoform X1 [KO:K10636] [EC:2.3.2.36]
103959825  E3 ubiquitin protein ligase RIN2-like isoform X1 [KO:K10636] [EC:2.3.2.36]
103963396  E3 ubiquitin protein ligase RIN2-like [KO:K10636] [EC:2.3.2.36]
103961957  E3 ubiquitin protein ligase RIN2-like isoform X1 [KO:K10636] [EC:2.3.2.36]
103927100  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
103932444  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
103961379  E3 ubiquitin-protein ligase CHIP-like [KO:K09561] [EC:2.3.2.27]
103967578  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
103960195  ubiquitin-conjugating enzyme E2 28 [KO:K06689] [EC:2.3.2.23]
103941719  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
103948066  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
103930228  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
103938409  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
103942580  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
103946119  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
103958173  ubiquitin-conjugating enzyme E2-17 kDa-like [KO:K06689] [EC:2.3.2.23]
103960203  ubiquitin-conjugating enzyme E2 28 [KO:K06689] [EC:2.3.2.23]
103963312  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
103965620  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
103965880  ubiquitin-conjugating enzyme E2-17 kDa [KO:K06689] [EC:2.3.2.23]
103965604  ubiquitin-conjugating enzyme E2 28-like [KO:K06689] [EC:2.3.2.23]
103957361  ubiquitin-conjugating enzyme E2 11-like [KO:K06689] [EC:2.3.2.23]
103963496  ubiquitin-conjugating enzyme E2 4-like isoform X1 [KO:K06689] [EC:2.3.2.23]
103942118  RING-box protein 1a-like [KO:K03868] [EC:2.3.2.32]
103964642  RING-box protein 1a [KO:K03868] [EC:2.3.2.32]
103932020  cullin-1-like isoform X1 [KO:K03347]
103958577  cullin-1-like isoform X1 [KO:K03347]
103943638  CUL1; uncharacterized protein LOC103943638 [KO:K03347]
103967396  cullin-1 [KO:K03347]
103952296  SKP1-like protein 1A [KO:K03094]
103953139  uncharacterized protein LOC103953139 [KO:K03094]
103927489  SKP1-like protein 1B [KO:K03094]
103928201  SKP1-like protein 11 [KO:K03094]
103933733  SKP1-like protein 11 [KO:K03094]
103946630  SKP1-like protein 1A [KO:K03094]
103965592  SKP1-like protein 1B [KO:K03094]
108866301  S-phase kinase-associated protein 1-like [KO:K03094]
103962385  SKP1-like protein 1A [KO:K03094]
103958459  SKP1-like protein 1B [KO:K03094]
103953452  SKP1-like protein 1A [KO:K03094]
103967768  SKP1-like protein 1A [KO:K03094]
103962057  SKP1-like protein 1A [KO:K03094]
103962058  SKP1-like protein 1A [KO:K03094]
103962061  SKP1-like protein 1A [KO:K03094]
103962088  SKP1-like protein 1A [KO:K03094]
Compound
C00076  Calcium cation
G00009   
G00010   
G00011   
G00012   
G10694   
Reference
PMID:19491040
  Authors
Naidoo N
  Title
ER and aging-Protein folding and the ER stress response.
  Journal
Ageing Res Rev 8:150-9 (2009)
DOI:10.1016/j.arr.2009.03.001
Reference
PMID:18023214
  Authors
Malhotra JD, Kaufman RJ
  Title
The endoplasmic reticulum and the unfolded protein response.
  Journal
Semin Cell Dev Biol 18:716-31 (2007)
DOI:10.1016/j.semcdb.2007.09.003
Reference
PMID:20347046
  Authors
Maattanen P, Gehring K, Bergeron JJ, Thomas DY
  Title
Protein quality control in the ER: the recognition of misfolded proteins.
  Journal
Semin Cell Dev Biol 21:500-11 (2010)
DOI:10.1016/j.semcdb.2010.03.006
Reference
PMID:20219571
  Authors
Stolz A, Wolf DH
  Title
Endoplasmic reticulum associated protein degradation: a chaperone assisted journey to hell.
  Journal
Biochim Biophys Acta 1803:694-705 (2010)
DOI:10.1016/j.bbamcr.2010.02.005
Reference
PMID:20112977
  Authors
Dejgaard K, Theberge JF, Heath-Engel H, Chevet E, Tremblay ML, Thomas DY
  Title
Organization of the Sec61 translocon, studied by high resolution native electrophoresis.
  Journal
J Proteome Res 9:1763-71 (2010)
DOI:10.1021/pr900900x
Related
pathway
pxb00510  N-Glycan biosynthesis
pxb03050  Proteasome
pxb03060  Protein export
KO pathway
ko04141   
LinkDB

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