KEGG ORTHOLOGY: K26502

ORTHOLOGY: K26502

Entry

K26502                      KO

Symbol

TMEM258

Name

transmembrane protein 258

Pathway

map00510

N-Glycan biosynthesis

map00513

Various types of N-glycan biosynthesis

map04141

Protein processing in endoplasmic reticulum

Reaction

R05976

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00510 N-Glycan biosynthesis
    K26502  TMEM258; transmembrane protein 258
   00513 Various types of N-glycan biosynthesis
    K26502  TMEM258; transmembrane protein 258
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K26502  TMEM258; transmembrane protein 258

Other DBs

GO:

0008250

TC:

9.B.142.3

Genes

HSA:	746(TMEM258)

PTR:	739125(TMEM258)

PPS:	100982055(TMEM258)

GGO:	101135352(TMEM258)

PON:	100436545(TMEM258)

PPYG:

129007405(TMEM258)

NLE:	100595774(TMEM258)

HMH:	116468866(TMEM258)

SSYN:

129485440(TMEM258)

MCC:	100689487(TMEM258)

MCF:	102119627(TMEM258) 102131576

MTHB:

126935538 126938618

MNI:	105469421(TMEM258)

CSAB:

103234205(TMEM258)

CATY:

105577576(TMEM258)

PANU:

101024632(TMEM258)

TGE:	112606129(TMEM258)

RRO:	104679376(TMEM258)

RBB:	108533604(TMEM258)

TFN:	117077316 117080263(TMEM258)

PTEH:

111524321(TMEM258)

CANG:

105512292(TMEM258)

CJC:	100389940(TMEM258)

SBQ:	101038966 101053028(TMEM258)

CIMI:

108286226(TMEM258)

ANAN:

105718625(TMEM258)

CSYR:

103253950

MMUR:

105878625(TMEM258)

LCAT:

123641267(TMEM258)

PCOQ:

105825050(TMEM258)

OGA:	100955275(TMEM258) 100961297

MMU:	69038(Tmem258)

MCAL:

110285843(Tmem258)

MPAH:

110332655(Tmem258)

RNO:	100363048(Tmem258l5) 499317(Tmem258) 502595(Tmem258l1) 679583(Tmem258l2) 680191(Tmem258l4) 686092(Tmem258b) 690138(Tmem258l3)

MCOC:

116103549(Tmem258)

ANU:	117693416 117693745(Tmem258) 117698764

MUN:	110541416 110548098(Tmem258) 110554592

CGE:	100755652 100774680 118237682

MAUA:

101828252 101833128 101843805(Tmem258)

PROB:

127228843(Tmem258)

PLEU:

114703502(Tmem258)

MORG:

121432511 121454673(Tmem258)

MFOT:

126498707 126510291

AAMP:

119799539 119803436(Tmem258) 119811115 119825730

NGI:	103729122(Tmem258)

HGL:	101698389(Tmem258)

CPOC:

100724454(Tmem258)

CCAN:

109685727(Tmem258)

DORD:

105980239 105995416(Tmem258)

DSP:	122099798 122105022(Tmem258) 122119354 122119355 122119356 122121064

PLOP:

125362344(Tmem258)

NCAR:

124960060

MMMA:

107135905(Tmem258) 107160459

OCU:

100353213

OPI:	101517552 101519980(TMEM258)

TUP:	102499782(TMEM258)

GVR:	103604813(TMEM258)

CFA:	102153475 119872320 476064(TMEM258)

CLUD:

112659420(TMEM258) 112672468 112679127 118355038

VVP:	112911071(TMEM258)

VLG:	121471344(TMEM258) 121485411 121486320 121493812

NPO:	129498816 129499011(TMEM258) 129516283 129519192 129523243

AML:	100470034(TMEM258)

UMR:	103656903 103677430 103678170(TMEM258) 121101078

UAH:	113246986(TMEM258) 113255907 113268159 113268554

UAR:	123785123(TMEM258) 123786805 123798617 123801232

ELK:	111149757 111152722

LLV:	125078521 125096466 125097289 125098314 125105199

MPUF:

101677453(TMEM258)

MNP:	132020171(TMEM258) 132022222

MLK:	131813719(TMEM258) 131828993 131840555

NVS:	122912989(TMEM258)

ORO:	101365838(TMEM258)

EJU:	114220209(TMEM258)

ZCA:	113914864(TMEM258)

MLX:	118015926(TMEM258)

NSU:	110575886(TMEM258)

LWW:	102738849(TMEM258)

FCA:	101083452(TMEM258)

PYU:	121043316(TMEM258)

PCOO:

112852145(TMEM258)

PBG:	122483868(TMEM258)

PVIV:

125146922(TMEM258)

LRUF:

124505090

PTG:	102952853(TMEM258)

PPAD:

109246558(TMEM258)

PUC:

125932553

AJU:

106986972

HHV:	120246185(TMEM258)

BTA:	767958(TMEM258)

BOM:	102274963(TMEM258)

BIU:	109554599(TMEM258)

BBUB:

102404330(TMEM258)

BBIS:

104998709(TMEM258)

CHX:	102177696(TMEM258)

OAS:	101108351(TMEM258)

BTAX:

128069036(TMEM258)

ODA:	120874545(TMEM258)

CCAD:

122431170(TMEM258)

MBEZ:

129548887(TMEM258) 129554020

SSC:	100517573(TMEM258)

CFR:	102505821(TMEM258)

CBAI:

105070108(TMEM258)

CDK:	105084327 105094874(TMEM258)

VPC:	102544627(TMEM258)

BACU:

103009584(TMEM258) 103010640

BMUS:

118899380(TMEM258) 118900670

LVE:	103069827 103084344(TMEM258)

OOR:	101275048(TMEM258)

DLE:	111183887(TMEM258)

PCAD:

102989809(TMEM258)

PSIU:

116757882(TMEM258)

NASI:

112402275(TMEM258)

ECB:	100062603(TMEM258)

EPZ:	103543088(TMEM258)

EAI:	106829004 106847589(TMEM258)

MYB:	102258627(TMEM258)

MYD:	102762397(TMEM258)

MMYO:

118649004(TMEM258)

MLF:	102435013(TMEM258)

MDT:	132241559(TMEM258)

PKL:	118707267(TMEM258)

EFUS:

103296729 103302486 103303330(TMEM258)

MNA:	107527687(TMEM258)

DRO:	112317162(TMEM258)

SHON:

118996939(TMEM258)

AJM:	119043685(TMEM258)

PDIC:

114500580(TMEM258) 114511223

PHAS:

123823698 123829491(TMEM258)

MMF:	118628304(TMEM258) 118633624

PPAM:

129062755(TMEM258)

HAI:	109389961(TMEM258)

RFQ:	117030882(TMEM258)

PALE:

102894828(TMEM258)

PGIG:

120600654(TMEM258)

PVP:	105297783(TMEM258)

RAY:	107501602(TMEM258)

MJV:	108392393(TMEM258)

TOD:	119250109(TMEM258) 119253200

SARA:

101540078(TMEM258)

SETR:

126017878(TMEM258)

LAV:	100653784(TMEM258)

TMU:	101351572 101354321 105756670

ETF:	101650190(TMEM258) 101651039

DNM:	101416755(TMEM258)

MDO:	100028506(TMEM258)

GAS:	123251599(TMEM258)

SHR:	100935260(TMEM258)

AFZ:

127541867

PCW:	110195524(TMEM258)

TVP:	118854356(TMEM258)

OAA:	107547481(TMEM258)

GGA:	422964(TMEM258)

PCOC:

116243014(TMEM258)

MGP:	100544959(TMEM258)

CJO:	107314212(TMEM258)

TPAI:

128087130(TMEM258)

LMUT:

125695350(TMEM258)

NMEL:

110400876(TMEM258)

APLA:

101791682(TMEM258)

ACYG:

106048301(TMEM258)

CATA:

118244726(TMEM258)

AFUL:

116490178(TMEM258)

TGU:	100218167(TMEM258)

LSR:	110467543(TMEM258)

SCAN:

103822153(TMEM258)

OTC:	121340130(TMEM258)

PRUF:

121355198(TMEM258)

GFR:	102036381(TMEM258)

FAB:	101810606(TMEM258)

OMA:	130253689(TMEM258)

PHI:	102103992(TMEM258)

PMAJ:

107206178(TMEM258)

CCAE:

111930431(TMEM258)

CCW:	120410123(TMEM258)

ETL:	114063361(TMEM258)

ZAB:	102066931(TMEM258)

ZLE:	135448951(TMEM258)

SVG:	106854710(TMEM258)

MMEA:

130580069(TMEM258)

HRT:	120753805(TMEM258)

SATI:

136362138(TMEM258)

FPG:	101924809(TMEM258)

FCH:	102045689(TMEM258)

NNT:	104406192(TMEM258)

SHAB:

115607018(TMEM258)

ACUN:

113481052(TMEM258)

TALA:

116961852(TMEM258)

ACHC:

115351600(TMEM258)

HLE:	104829805(TMEM258)

AGEN:

126047150

GCL:

127017396

PCRI:

104028979(TMEM258)

CLV:	106146027(TMEM258)

MUI:	104541341(TMEM258)

PLET:

104620137(TMEM258)

CUCA:

104064415(TMEM258)

RTD:	128909649(TMEM258)

AAM:	106484372(TMEM258)

AROW:

112978449(TMEM258)

NPD:	112952720(TMEM258)

TGT:	104578816(TMEM258)

DNE:	112988644(TMEM258)

SCAM:

104141093(TMEM258)

ASN:	102378782(TMEM258)

AMJ:	102564520(TMEM258)

CPOO:

109318221(TMEM258)

GGN:	109289084(TMEM258)

PSS:	102460619(TMEM258)

CMY:	114020389(TMEM258)

CCAY:

125638476(TMEM258)

DCC:	119857664(TMEM258)

CPIC:

103306552(TMEM258)

TST:	117877431(TMEM258)

CABI:

116825306(TMEM258)

MRV:	120405220(TMEM258)

ACS:	107983189(tmem258)

ASAO:

132762069 132772008(TMEM258)

PVT:	110086186(TMEM258)

SUND:

121919311(TMEM258)

PBI:	107326371(TMEM258)

PMUR:

107287962(TMEM258)

CTIG:

120312435(TMEM258)

TSR:	106539941(TMEM258)

PGUT:

117667032(TMEM258)

APRI:

131184380(TMEM258)

PTEX:

113449117(TMEM258)

NSS:	113421928(TMEM258)

VKO:	123021165(TMEM258)

PMUA:

114600586(TMEM258)

PRAF:

128417705(TMEM258)

ZVI:	118089081(TMEM258)

HCG:	128340104(TMEM258)

GJA:	107109698(TMEM258)

STOW:

125426021(TMEM258)

XLA:	444157(tmem258.L)

XTR:	448722(tmem258)

NPR:	108794180(TMEM258)

RTEM:

120917262(TMEM258)

BBUF:

120980345(TMEM258)

BGAR:

122920856(TMEM258)

MUO:	115468972(TMEM258)

GSH:	117352209(TMEM258)

DRE:	393742(tmem258)

SRX:	107732277 107734672

SANH:

107655160 107674840

SGH:	107551429 107561170

CCAR:

109051056 109051058

CAUA:

113042890 113042903 113066525 113080821

CGIB:

127947484 128014183

PTET:

122330692(tmem258)

LROH:

127156852(tmem258)

OMC:	131534693(tmem258)

PPRM:

120471776(tmem258)

RKG:	130106502(tmem258)

MAMB:

125246713(tmem258)

CIDE:

127507571

CERY:

137015187(tmem258)

MASI:

127435926 127437197

TROS:

130551813(tmem258)

TDW:	130413994(tmem258)

IPU:	100528560(tmem258)

IFU:	128618144(tmem258)

PHYP:

113529809(tmem258)

SMEO:

124391916(tmem258)

TFD:	113660042(tmem258)

TVC:	132856714(tmem258)

TRN:	134321792(tmem258)

AMEX:

103044773(tmem258)

CMAO:

118811332(tmem258)

EEE:	113571405(tmem258)

CHAR:

105904232(tmem258)

TRU:	115251023(tmem258)

TFS:	130535969(tmem258)

LCO:	104937139(tmem258)

NCC:	104945748(tmem258)

TBEN:

117491964(tmem258)

CGOB:

115010137(tmem258)

PGEO:

117448583(tmem258)

GACU:

117538826(tmem258)

EMAC:

134859214(tmem258)

ELY:	117261742(tmem258)

EFO:	125888039(tmem258)

PLEP:

121950089(tmem258)

SLUC:

116038462(tmem258)

ECRA:

117949012(tmem258)

ESP:	116674431 116694373(tmem258)

PFLV:

114560251(tmem258)

GAT:	120808826(tmem258)

PPUG:

119196649(tmem258)

AFB:	129108201(tmem258)

CLUM:

117732815(tmem258)

PSWI:

130195301(tmem258)

MSAM:

119894003(tmem258)

SCHU:

122875438(tmem258)

CUD:	121515226(tmem258)

ALAT:

119023770(tmem258)

ASTR:

137594560(tmem258)

MZE:	101477853(tmem258)

ONL:	100699544(tmem258)

OAU:	116326208(tmem258)

OLA:	105354217(tmem258)

CSAI:

133444175(tmem258)

XMA:	102222118(tmem258)

XCO:	114150340(tmem258)

XHE:	116732375(tmem258)

PRET:

103466516(tmem258)

PFOR:

103141294(tmem258)

PLAI:

106955827(tmem258)

PMEI:

106921855(tmem258)

GAF:	122835708(tmem258)

PPRL:

129367015(tmem258)

CVG:	107096153(tmem258)

CTUL:

119778812(tmem258)

GMU:	124857681(tmem258)

NFU:	107388691(tmem258)

KMR:	108229868(tmem258)

ALIM:

106521197(tmem258)

NWH:	119415783(tmem258)

AOCE:

111582138(tmem258)

CSEM:

103380273(tmem258)

POV:	109623553(tmem258)

SSEN:

122760528(tmem258)

HHIP:

117762904(tmem258)

HSP:	118110266(tmem258)

PPLT:

128445046(tmem258)

SMAU:

118314704(tmem258)

LCF:

108886766

SDU:	111229872(tmem258)

SLAL:

111666881(tmem258)

XGL:	120793588(tmem258)

HCQ:	109507592(tmem258)

SSCV:

125970812

SBIA:

133501951(tmem258)

PEE:	133402375(tmem258)

PTAO:

133478489(tmem258)

BPEC:

110167703(tmem258)

MALB:

109971266(tmem258)

BSPL:

114857859(tmem258)

SJO:	128358500(tmem258)

SASA:

106561832 106584809

STRU:

115192948 115197730

OTW:	112221698(tmem258) 112263149

OMY:	110501329(tmem258) 110521162

OGO:	124031553(tmem258) 124037449

ONE:	115122625 115123753

OKI:	109867326(tmem258) 109883595

OKE:	118379501 118396016(tmem258)

SALP:

111958549(tmem258)

SNH:	120052279 120066768(tmem258)

CCLU:

121531244(tmem258) 121540771

ELS:	105018070(tmem258)

SFM:	108941024(tmem258)

PKI:	111834515(tmem258)

AANG:

118226767(tmem258)

PSPA:

121294722 121329652

ARUT:

117432462 117434759(tmem258)

PSEX:

120530778(tmem258)

LCM:	102348615(TMEM258)

CMK:	103174859(tmem258)

RTP:	109921165(tmem258)

CPLA:

122557875(tmem258)

HOC:	132824405(tmem258)

LERI:

129705774(tmem258)

PMRN:

116955707(TMEM258)

LRJ:	133347735(TMEM258)

SPU:

100893832

DME:	Dmel_CG9669(kud)

DER:

6544151

DSE:

6606017

DSI:	Dsimw501_GD12439(Dsim_GD12439)

DYA:	Dyak_GE22186

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI12877

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108355829 108373589

AOQ:

129241043

TDA:	119672204 119672206

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006914

CPII:

CNS:

BCOO:

LLL:

AME:

ACER:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

SOC:

MPHA:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:	105672051(kud)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

AGIF:

CINS:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:	103312430 103312999

DPA:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

DCOR:

APLN:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_204104

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:	113518879 128202633

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

ACOO:

DVT:

BTAB:

DCI:	103521929 103521930 108251859

CLEC:

106664600

HHAL:

106690526(kud)

NLU:

111055961

HVI:

124365477

MQU:

128994002

PHU:	Phum_PHUM537120

FOC:

TPAL:

BROR:

IEL:

DPX:	DAPPUDRAFT_222109

PVM:

PJA:

PCHN:

PMOO:

PTRU:

MNZ:

MRJ:	136832772(kud)

EAF:

ISC:

DSV:

RMP:

VDE:

VJA:

DPTE:

CSCU:

SDM:

PMEO:

CEL:	CELE_Y57E12AM.1(tmem-258)

CBR:

CBG_19073

CRQ:	GCK72_018045

BMY:	BM_BM6900(Bm6900)

LOA:	LOAG_01399

LGI:	LOTGIDRAFT_196219

GAE:

CANU:

MYI:

MMER:

OSN:

LAK:

EGL:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HMG:

HSY:

TAD:	TRIADDRAFT_33018

AQU:

ATH:

ALY:

CRB:

CSAT:

104717226 104721894 104730351

EUS:	EUTSA_v10026717mg

BRP:	103853335 103861900

BNA:	106372113 106386267 106386343 106399540 125590138

BOE:	106304434 106310884 106334017

RSZ:	108821673 108843562 108851876 130502414 130506446

THJ:	104814622 104820022

CIT:

102611285

CIC:	CICLE_v10010087mg

PVY:	116110263 116119274

MINC:

123194309 123200012

TCC:

18588394

GRA:	105768760 105784340

GHI:	107893331 107907140 107932009 107937709

GAB:	108462982 108485442

HSYR:

120124167 120166294 120169289 120180049 120192264 120201314 120202129 120218689

DZI:	111284797 111303110

EGR:	104436484 104438325 120291217

GMX:	100306485 106794096

GSJ:	114381173 114392517

PVU:	PHAVU_003G136800g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:

ADU:

AIP:

AHF:	112697149 112697171 112723633

LANG:

109347456 109362539

PCIN:

129320528

QSA:	O6P43_002758 O6P43_022413

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:

MSYL:

PXB:	103943995 103951860

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

MEAN:

JCU:	105637884 105639365

HBR:	110650124 110651617

MESC:

110602943 110610839

POP:	18098239 7484652

PEU:	105110121 105116890 105128339

PALZ:

118038786 118047972

PNZ:	133689036 133698943

JRE:	108997834 108997836

CILL:

CAVE:

QSU:

QLO:

TWL:	119997660 120005727

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:	107768061 107778193 107812608 107821237 107832291

NSY:	104214357 104217066

NTO:	104087914 104089603 104092976

NAU:	109207871 109216131 109228482

INI:	109148084 109186636

ITR:	115998637 116014180

SIND:

105161851

OEU:	111366118 111397160

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HAN:	110893221 110894389 118490105

ECAD:

122600762

LSV:

111905587

CCAV:

112500864

DCR:	108192514 108197442

CSIN:

114285091

RVL:

131320073

AEW:	130782925 130784563

BVG:

104884244

SOE:

110798539

CQI:	110683087 110712939

ATRI:

MOF:

NNU:

MING:

TSS:	122653802 122656166

PSOM:

113300505 113317589 113349523 113353424

OSA:

OBR:

OGL:

BDI:

ATS:	109737814 109739958 109755666

TDC:	119316681 119322634 119331649 119339994

TAES:

123137030 123144407 123148027 123160775 123169477

TUA:	125512391 125524622

LPER:

127307781 127313222

LRD:	124683682 124686863 124686874

SBI:

8061992

ZMA:	100276129 100277314

MFLO:

SITA:

SVS:

PVIR:

PHAI:

PDA:	103702034 103709575

EGU:	105040434 105047979

MUS:	103982303 103987031

ZOF:	121971593 121976063

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_141036

PPP:

112288389

VCN:	VOLCADRAFT_76469

RIE:	OCT59_015053

SRE:	PTSG_06091

ACAN:

ACA1_192040

NGD:	NGA_0491920

» show all

Reference

PMID:27974209

Authors

Graham DB, Lefkovith A, Deelen P, de Klein N, Varma M, Boroughs A, Desch AN, Ng ACY, Guzman G, Schenone M, Petersen CP, Bhan AK, Rivas MA, Daly MJ, Carr SA, Wijmenga C, Xavier RJ

Title

TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation.

Journal

Cell Rep 17:2955-2965 (2016)
DOI:10.1016/j.celrep.2016.11.042

Sequence

[hsa:746]

Reference

PMID:31831667

Authors

Ramirez AS, Kowal J, Locher KP

Title

Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B.

Journal

Science 366:1372-1375 (2019)
DOI:10.1126/science.aaz3505

LinkDB

DBGET integrated database retrieval system