KEGG   PATHWAY: rhf00230
Entry
rhf00230                    Pathway                                
Name
Purine metabolism - Rhodoferax sediminis CHu59-6-5
Class
Metabolism; Nucleotide metabolism
Pathway map
rhf00230  Purine metabolism
rhf00230

Module
rhf_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rhf00230]
rhf_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rhf00230]
rhf_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rhf00230]
rhf_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rhf00230]
rhf_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rhf00230]
rhf_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rhf00230]
rhf_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rhf00230]
Other DBs
GO: 0006163 0042278
Organism
Rhodoferax sediminis CHu59-6-5 [GN:rhf]
Gene
EUB48_14065  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EUB48_05760  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
EUB48_06045  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
EUB48_12645  prs; ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
EUB48_16800  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
EUB48_10850  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
EUB48_05600  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
EUB48_10560  phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
EUB48_06260  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
EUB48_00865  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
EUB48_00860  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
EUB48_00850  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
EUB48_00675  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
EUB48_18100  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
EUB48_00045  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
EUB48_02750  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
EUB48_12505  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
EUB48_16840  pyrimidine/purine nucleoside phosphorylase [KO:K09913] [EC:2.4.2.1 2.4.2.2]
EUB48_11950  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
EUB48_10265  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
EUB48_11425  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
EUB48_06195  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
EUB48_07010  xdhA; xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
EUB48_07005  xdhB; xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
EUB48_08535  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
EUB48_08540  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
EUB48_08530  (2Fe-2S)-binding protein [KO:K13483]
EUB48_10270  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
EUB48_06450  GMP reductase [KO:K00364] [EC:1.7.1.7]
EUB48_17100  guaD; guanine deaminase [KO:K01487] [EC:3.5.4.3]
EUB48_06170  guanylate kinase [KO:K00942] [EC:2.7.4.8]
EUB48_18225  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
EUB48_08365  adenosylcobalamin-dependent ribonucleoside-diphosphate reductase [KO:K00525] [EC:1.17.4.1]
EUB48_18230  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
EUB48_03825  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
EUB48_06160  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
EUB48_09425  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
EUB48_09185  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K00951] [EC:2.7.6.5]
EUB48_08755  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
EUB48_08925  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
EUB48_10310  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
EUB48_11350  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
EUB48_18240  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
EUB48_19150  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
EUB48_17110  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
EUB48_11000  adenylate kinase [KO:K00939] [EC:2.7.4.3]
EUB48_17030  symmetrical bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
EUB48_09965  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
EUB48_09970  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
EUB48_17190  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
EUB48_20765  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
EUB48_17200  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
EUB48_13925  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
EUB48_13920  urease subunit beta [KO:K01429] [EC:3.5.1.5]
EUB48_13915  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rhf00030  Pentose phosphate pathway
rhf00220  Arginine biosynthesis
rhf00250  Alanine, aspartate and glutamate metabolism
rhf00260  Glycine, serine and threonine metabolism
rhf00340  Histidine metabolism
rhf00630  Glyoxylate and dicarboxylate metabolism
rhf00730  Thiamine metabolism
rhf00740  Riboflavin metabolism
rhf00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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