KEGG   PATHWAY: roh00230
Entry
roh00230                    Pathway                                
Name
Purine metabolism - Roseovarius sp. THAF27
Class
Metabolism; Nucleotide metabolism
Pathway map
roh00230  Purine metabolism
roh00230

Module
roh_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:roh00230]
roh_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:roh00230]
roh_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:roh00230]
roh_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:roh00230]
roh_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:roh00230]
roh_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:roh00230]
roh_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:roh00230]
Other DBs
GO: 0006163 0042278
Organism
Roseovarius sp. THAF27 [GN:roh]
Gene
FIU89_09245  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
FIU89_04550  deoB; Phosphopentomutase [KO:K01839] [EC:5.4.2.7]
FIU89_01735  algC; Phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
FIU89_02965  prs; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
FIU89_11910  purF1; Amidophosphoribosyltransferase precursor [KO:K00764] [EC:2.4.2.14]
FIU89_06750  purD; Phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
FIU89_11045  purN; Phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
FIU89_08650  purL; Phosphoribosylformylglycinamidine synthase 2 [KO:K23269] [EC:6.3.5.3]
FIU89_09120  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
FIU89_09125  purQ; Phosphoribosylformylglycinamidine synthase 1 [KO:K23265] [EC:6.3.5.3 3.5.1.2]
FIU89_11050  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
FIU89_03035  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
FIU89_03030  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
FIU89_09110  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
FIU89_07925  purB; Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
FIU89_00150  purH; Bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
FIU89_01880  apt; Adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
FIU89_04660  yfkN2; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
FIU89_13070  yfkN3; Trifunctional nucleotide phosphoesterase protein YfkN precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
FIU89_11935  surE; 5'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
FIU89_18815  deoD; Purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
FIU89_03205  yfiH; Laccase domain protein YfiH [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
FIU89_09535  guaB1; Inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
FIU89_08585  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
FIU89_20415  Non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
FIU89_08805  gpt; Xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
FIU89_14350  ndhF; Nicotinate dehydrogenase FAD-subunit [KO:K13479] [EC:1.17.1.4]
FIU89_04930  xdhA; Xanthine dehydrogenase molybdenum-binding subunit [KO:K11177] [EC:1.17.1.4]
FIU89_04935  hcrB; 4-hydroxybenzoyl-CoA reductase subunit beta [KO:K11178] [EC:1.17.1.4]
FIU89_04940  ndhS1; Nicotinate dehydrogenase small FeS subunit [KO:K13483]
FIU89_01035  guaA2; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
FIU89_09990  guaA3; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
FIU89_06655  guaD; Guanine deaminase [KO:K01487] [EC:3.5.4.3]
FIU89_10210  gmk; Guanylate kinase [KO:K00942] [EC:2.7.4.8]
FIU89_04695  nrdZ; Ribonucleoside-diphosphate reductase NrdZ [KO:K00525] [EC:1.17.4.1]
FIU89_08835  nrdJ; Vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
FIU89_05250  nrdE2; Ribonucleoside-diphosphate reductase subunit alpha 2 [KO:K00525] [EC:1.17.4.1]
FIU89_05255  nrdF2; Ribonucleoside-diphosphate reductase subunit beta nrdF2 [KO:K00526] [EC:1.17.4.1]
FIU89_10615  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
FIU89_20240  hypothetical protein [KO:K06952] [EC:3.1.3.89]
FIU89_17685  rsh; GTP pyrophosphokinase rsh [KO:K01139] [EC:2.7.6.5 3.1.7.2]
FIU89_10885  gppA2; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIU89_07070  gppA1; Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
FIU89_05190  invasion protein regulator [KO:K01768] [EC:4.6.1.1]
FIU89_12705  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
FIU89_01505  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
FIU89_02135  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase precursor [KO:K01119] [EC:3.1.4.16 3.1.3.6]
FIU89_06675  hypothetical protein [KO:K09769] [EC:3.1.4.16]
FIU89_16160  adk2; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
FIU89_07380  adk1; Adenylate kinase [KO:K00939] [EC:2.7.4.3]
FIU89_08490  mazG; Nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
FIU89_06605  cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [KO:K03651] [EC:3.1.4.53]
FIU89_03150  sat_cysC; putative bifunctional SAT/APS kinase [KO:K00958] [EC:2.7.7.4]
FIU89_10320  Asp/Glu/Hydantoin racemase [KO:K16841] [EC:5.1.99.3]
FIU89_10330  Polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
FIU89_10340  hypothetical protein [KO:K14977] [EC:3.5.3.26]
FIU89_10335  allA; Ureidoglycolate lyase [KO:K01483] [EC:4.3.2.3]
FIU89_13540  ureC1; Urease subunit alpha 1 [KO:K01428] [EC:3.5.1.5]
FIU89_13550  ureB1; Urease subunit beta 1 [KO:K01429] [EC:3.5.1.5]
FIU89_13560  ureA; Urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
roh00030  Pentose phosphate pathway
roh00220  Arginine biosynthesis
roh00250  Alanine, aspartate and glutamate metabolism
roh00260  Glycine, serine and threonine metabolism
roh00340  Histidine metabolism
roh00630  Glyoxylate and dicarboxylate metabolism
roh00730  Thiamine metabolism
roh00740  Riboflavin metabolism
roh00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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