KEGG   PATHWAY: rrz00230
Entry
rrz00230                    Pathway                                
Name
Purine metabolism - Rhodococcus ruber
Class
Metabolism; Nucleotide metabolism
Pathway map
rrz00230  Purine metabolism
rrz00230

Module
rrz_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rrz00230]
rrz_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rrz00230]
rrz_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rrz00230]
rrz_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rrz00230]
rrz_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rrz00230]
rrz_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rrz00230]
Other DBs
GO: 0006163 0042278
Organism
Rhodococcus ruber [GN:rrz]
Gene
CS378_06335  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CS378_22410  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CS378_20690  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CS378_20185  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CS378_21930  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CS378_09770  formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
CS378_20670  phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
CS378_20610  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
CS378_20615  phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
CS378_20695  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CS378_06840  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CS378_06835  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CS378_20375  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CS378_20200  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CS378_21935  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CS378_02275  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CS378_17875  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CS378_09135  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
CS378_09705  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
CS378_07090  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CS378_04970  peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CS378_20400  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
CS378_19025  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CS378_07425  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
CS378_07430  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CS378_00865  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CS378_00150  rdgB; non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CS378_06190  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
CS378_06195  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
CS378_06200  (2Fe-2S)-binding protein [KO:K13483]
CS378_07415  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
CS378_23945  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
CS378_03740  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
CS378_02855  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CS378_06175  class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CS378_09775  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
CS378_06170  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CS378_16190  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
CS378_05590  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CS378_02280  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CS378_08825  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CS378_22610  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CS378_20360  GTP pyrophosphokinase [KO:K07816] [EC:2.7.6.5]
CS378_13140  (p)ppGpp synthetase [KO:K07816] [EC:2.7.6.5]
CS378_11455  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CS378_12440  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CS378_13210  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CS378_09550  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CS378_09810  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CS378_05235  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CS378_07170  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CS378_23700  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CS378_07655  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CS378_22450  nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
CS378_24115  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
CS378_02195  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
CS378_25055  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
CS378_05735  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CS378_05730  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
CS378_25050  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CS378_18990  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rrz00030  Pentose phosphate pathway
rrz00220  Arginine biosynthesis
rrz00250  Alanine, aspartate and glutamate metabolism
rrz00260  Glycine, serine and threonine metabolism
rrz00340  Histidine metabolism
rrz00630  Glyoxylate and dicarboxylate metabolism
rrz00730  Thiamine metabolism
rrz00740  Riboflavin metabolism
rrz00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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