KEGG   PATHWAY: rsan00564
Entry
rsan00564                   Pathway                                
Name
Glycerophospholipid metabolism - Rhipicephalus sanguineus (brown dog tick)
Class
Metabolism; Lipid metabolism
Pathway map
rsan00564  Glycerophospholipid metabolism
rsan00564

Module
rsan_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:rsan00564]
rsan_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:rsan00564]
Other DBs
GO: 0006650
Organism
Rhipicephalus sanguineus (brown dog tick) [GN:rsan]
Gene
119393982  glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
119383654  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
119383819  LOW QUALITY PROTEIN: glycerol-3-phosphate dehydrogenase, mitochondrial-like [KO:K00111] [EC:1.1.5.3]
119394618  glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
119379195  glycerol-3-phosphate acyltransferase 1, mitochondrial isoform X1 [KO:K00629] [EC:2.3.1.15]
119379107  glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
119378335  1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
119406370  1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
119406371  LOW QUALITY PROTEIN: 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
119383200  lysophospholipid acyltransferase 6 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
119374048  dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
119399329  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
119372436  uncharacterized protein LOC119372436 [KO:K01080] [EC:3.1.3.4]
119404454  phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
119405085  putative phosphatidate phosphatase isoform X1 [KO:K01080] [EC:3.1.3.4]
119407049  phospholipid phosphatase homolog 1.2 homolog [KO:K01080] [EC:3.1.3.4]
119374315  phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
119396776  diacylglycerol kinase theta isoform X1 [KO:K00901] [EC:2.7.1.107]
119386294  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
119387610  diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
119388252  diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
119401738  diacylglycerol kinase zeta isoform X1 [KO:K00901] [EC:2.7.1.107]
119393244  diacylglycerol kinase beta isoform X1 [KO:K00901] [EC:2.7.1.107]
119382702  choline/ethanolaminephosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
119402104  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
119402111  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
119403327  phospholipase D1 [KO:K01115] [EC:3.1.4.4]
119401539  5'-3' exonuclease PLD3 isoform X1 [KO:K16860] [EC:3.1.4.4]
119403084  5'-3' exonuclease PLD3 [KO:K16860] [EC:3.1.4.4]
119399051  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
119372418  group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
119376249  uncharacterized protein LOC119376249 isoform X1 [KO:K01047] [EC:3.1.1.4]
119376258  uncharacterized protein LOC119376258 isoform X1 [KO:K01047] [EC:3.1.1.4]
119377508  uncharacterized protein LOC119377508 isoform X1 [KO:K01047] [EC:3.1.1.4]
119377518  group 3 secretory phospholipase A2 isoform X1 [KO:K01047] [EC:3.1.1.4]
119393583  group 3 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
119393584  phospholipase A2-like isoform X1 [KO:K01047] [EC:3.1.1.4]
119393585  uncharacterized protein LOC119393585 isoform X1 [KO:K01047] [EC:3.1.1.4]
125758480  basic phospholipase A2 PA-5-like [KO:K01047] [EC:3.1.1.4]
119389286  acidic phospholipase A2 PA4 [KO:K01047] [EC:3.1.1.4]
119400521  85/88 kDa calcium-independent phospholipase A2 isoform X2 [KO:K16343] [EC:3.1.1.4]
119373476  lysophosphatidylcholine acyltransferase 1 isoform X2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
119390967  lysophospholipid acyltransferase 5 isoform X7 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
119404710  phospholipase A2 group XV [KO:K06129] [EC:3.1.1.5]
119372580  acyl-protein thioesterase 1 [KO:K06130] [EC:3.1.1.5]
119399743  neuropathy target esterase sws isoform X1 [KO:K14676] [EC:3.1.1.5]
119389923  glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
119385612  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119371672  acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
119386934  acetylcholinesterase isoform X1 [KO:K01049] [EC:3.1.1.7]
119402046  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119402047  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119402412  cholinesterase 2 isoform X2 [KO:K01049] [EC:3.1.1.7]
119375945  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119375946  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377294  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377296  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377298  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377300  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377624  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119377731  cholinesterase 1 [KO:K01049] [EC:3.1.1.7]
119404292  uncharacterized protein LOC119404292 [KO:K01049] [EC:3.1.1.7]
119404296  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119404550  cholinesterase [KO:K01049] [EC:3.1.1.7]
119392806  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119393085  acetylcholinesterase-1 [KO:K01049] [EC:3.1.1.7]
119393270  acetylcholinesterase-1 isoform X2 [KO:K01049] [EC:3.1.1.7]
119393274  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
119393277  acetylcholinesterase isoform X2 [KO:K01049] [EC:3.1.1.7]
119393278  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119393279  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119393338  carboxylesterase 5A [KO:K01049] [EC:3.1.1.7]
119393858  acetylcholinesterase-like [KO:K01049] [EC:3.1.1.7]
119406800  phenmedipham hydrolase-like [KO:K01049] [EC:3.1.1.7]
119394601  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119394613  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119394651  LOW QUALITY PROTEIN: acetylcholinesterase-1 [KO:K01049] [EC:3.1.1.7]
119394658  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119396136  acetylcholinesterase [KO:K01049] [EC:3.1.1.7]
119383474  choline/ethanolamine kinase isoform X1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
119387641  uncharacterized protein LOC119387641 isoform X1 [KO:K00968] [EC:2.7.7.15]
119384085  choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
119406909  LOW QUALITY PROTEIN: ethanolaminephosphotransferase 1-like [KO:K00993] [EC:2.7.8.1]
119383960  ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
119399641  ethanolamine-phosphate cytidylyltransferase isoform X1 [KO:K00967] [EC:2.7.7.14]
119396650  uncharacterized protein LOC119396650 [KO:K05929] [EC:2.1.1.103]
119376410  5-phosphohydroxy-L-lysine phospho-lyase [KO:K14286] [EC:4.2.3.2]
119379596  5-phosphohydroxy-L-lysine phospho-lyase isoform X1 [KO:K14286] [EC:4.2.3.2]
119401653  phosphatidate cytidylyltransferase, photoreceptor-specific [KO:K00981] [EC:2.7.7.41]
119383187  phosphatidylserine synthase [KO:K08729] [EC:2.7.8.-]
119389629  phosphatidylserine decarboxylase proenzyme, mitochondrial isoform X1 [KO:K01613] [EC:4.1.1.65]
119400378  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial-like [KO:K00995] [EC:2.7.8.5]
119374123  probable cardiolipin synthase (CMP-forming) [KO:K08744] [EC:2.7.8.41]
119396369  tafazzin isoform X1 [KO:K13511] [EC:2.3.1.-]
119376252  LOW QUALITY PROTEIN: acyl-CoA:lysophosphatidylglycerol acyltransferase 1-like [KO:K13514] [EC:2.3.1.-]
119377510  acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform X1 [KO:K13514] [EC:2.3.1.-]
119399939  lysophospholipid acyltransferase 7 [KO:K13516] [EC:2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
rsan00010  Glycolysis / Gluconeogenesis
rsan00260  Glycine, serine and threonine metabolism
rsan00561  Glycerolipid metabolism
rsan00562  Inositol phosphate metabolism
rsan00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
rsan00565  Ether lipid metabolism
rsan00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

DBGET integrated database retrieval system