KEGG   PATHWAY: rsk00630
Entry
rsk00630                    Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Cereibacter sphaeroides KD131
Class
Metabolism; Carbohydrate metabolism
Pathway map
rsk00630  Glyoxylate and dicarboxylate metabolism
rsk00630

Module
rsk_M00373  Ethylmalonyl pathway [PATH:rsk00630]
rsk_M00621  Glycine cleavage system [PATH:rsk00630]
rsk_M00741  Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA [PATH:rsk00630]
Other DBs
GO: 0046487 0043648
Organism
Cereibacter sphaeroides KD131 [GN:rsk]
Gene
RSKD131_1919  Acetyl-coenzyme A synthetase [KO:K01895] [EC:6.2.1.1]
RSKD131_0281  Malate synthase G [KO:K01638] [EC:2.3.3.9]
RSKD131_2360  Malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
RSKD131_0296  Citrate synthase [KO:K01647] [EC:2.3.3.1]
RSKD131_0109  Aconitase [KO:K01681] [EC:4.2.1.3]
RSKD131_2752  Acetyl-CoA acetyltransferases precursor [KO:K00626] [EC:2.3.1.9]
RSKD131_3358  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RSKD131_0513  Acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
RSKD131_2104  Acetyl-CoA acetyltransferase precursor [KO:K00626] [EC:2.3.1.9]
RSKD131_2105  acetoacetyl-CoA reductase [KO:K00023] [EC:1.1.1.36]
RSKD131_0627  MaoC domain protein dehydratase [KO:K17865] [EC:4.2.1.55]
RSKD131_2352  Crotonyl-CoA reductase [KO:K14446] [EC:1.3.1.85]
RSKD131_2174  Methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
RSKD131_2353  Methylmalonyl-CoA mutase [KO:K14447] [EC:5.4.99.63]
RSKD131_3079  Isovaleryl-CoA dehydrogenase [KO:K14448] [EC:1.3.8.12]
RSKD131_2365  MaoC domain protein dehydratase [KO:K14449] [EC:4.2.1.148]
RSKD131_0071  Citrate (Pro-3S)-lyase [KO:K08691] [EC:4.1.3.24 4.1.3.25]
RSKD131_2362  Citrate (Pro-3S)-lyase [KO:K14451] [EC:3.1.2.30]
RSKD131_0505  Propionyl-CoA carboxylase alpha subunit [KO:K01965] [EC:6.4.1.3]
RSKD131_0500  Carboxyl transferase [KO:K01966] [EC:6.4.1.3 2.1.3.15]
RSKD131_0507  Methylmalonyl-CoA mutase [KO:K01847] [EC:5.4.99.2]
RSKD131_2413  FAD linked oxidase domain protein [KO:K00104] [EC:1.1.99.14]
RSKD131_2412  FAD linked oxidase domain protein [KO:K11472] [EC:1.1.99.14]
RSKD131_2411  Glycolate oxidase iron-sulfur subunit [KO:K11473] [EC:1.1.99.14]
RSKD131_1085  Catalase [KO:K03781] [EC:1.11.1.6]
RSKD131_0692  Catalase [KO:K03781] [EC:1.11.1.6]
RSKD131_0635  Glyoxylate reductase [KO:K00015] [EC:1.1.1.26]
RSKD131_3608  D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [KO:K12972] [EC:1.1.1.79 1.1.1.81]
RSKD131_2677  Phosphoglycolate phosphatase [KO:K01091] [EC:3.1.3.18]
RSKD131_0819  HAD-superfamily hydrolase, subfamily IA, variant 3 [KO:K01091] [EC:3.1.3.18]
RSKD131_1745  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K01091] [EC:3.1.3.18]
RSKD131_2681  Ribulose bisphosphate carboxylase large chain [KO:K01601] [EC:4.1.1.39]
RSKD131_3446  Ribulose bisphosphate carboxylase [KO:K01601] [EC:4.1.1.39]
RSKD131_2680  Ribulose bisphosphate carboxylase small chain 1 [KO:K01602] [EC:4.1.1.39]
RSKD131_1570  Aminotransferase, class V [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
RSKD131_1706  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RSKD131_1704  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RSKD131_0641  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RSKD131_1485  Glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RSKD131_2965  L-glutamine synthetase [KO:K01915] [EC:6.3.1.2]
RSKD131_2189  Serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
RSKD131_0511  Glycine dehydrogenase [KO:K00281] [EC:1.4.4.2]
RSKD131_0509  Aminomethyltransferase [KO:K00605] [EC:2.1.2.10]
RSKD131_1290  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RSKD131_2354  Dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
RSKD131_0510  Glycine cleavage system H protein [KO:K02437]
RSKD131_3245  Hydroxypyruvate reductase [KO:K11529] [EC:2.7.1.165]
RSKD131_3318  Fumarase alpha subunit [KO:K03779] [EC:4.2.1.32]
RSKD131_3317  Fe-S type hydro-lyases tartrate/fumarate beta region precursor [KO:K03780] [EC:4.2.1.32]
RSKD131_3555  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RSKD131_4374  hypothetical protein [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RSKD131_3554  Tartrate dehydrogenase [KO:K07246] [EC:1.1.1.93 4.1.1.73 1.1.1.83]
RSKD131_0956  2-keto-3-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
RSKD131_2478  Formate dehydrogenase delta subunit [KO:K00126] [EC:1.17.1.9]
RSKD131_2476  Formate dehydrogenase, alpha subunit [KO:K00123] [EC:1.17.1.9]
RSKD131_2475  NADH dehydrogenase [KO:K00124]
RSKD131_2474  NADH dehydrogenase (Ubiquinone), 24 kDa subunit [KO:K00127]
RSKD131_2403  esterase/lipase/thioesterase [KO:K01432] [EC:3.5.1.9]
RSKD131_2334  Formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
RSKD131_3675  Acetamidase/Formamidase [KO:K01455] [EC:3.5.1.49]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
PMID:10978349
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
PMID:18065535
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
PMID:18819910
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
PMID:16407450
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
PMID:21252347
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
PMID:11513957
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
rsk00010  Glycolysis / Gluconeogenesis
rsk00020  Citrate cycle (TCA cycle)
rsk00030  Pentose phosphate pathway
rsk00053  Ascorbate and aldarate metabolism
rsk00071  Fatty acid degradation
rsk00230  Purine metabolism
rsk00250  Alanine, aspartate and glutamate metabolism
rsk00260  Glycine, serine and threonine metabolism
rsk00620  Pyruvate metabolism
rsk00710  Carbon fixation by Calvin cycle
rsk00750  Vitamin B6 metabolism
rsk00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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