KEGG   PATHWAY: rso00230
Entry
rso00230                    Pathway                                
Name
Purine metabolism - Ralstonia pseudosolanacearum GMI1000
Class
Metabolism; Nucleotide metabolism
Pathway map
rso00230  Purine metabolism
rso00230

Module
rso_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rso00230]
rso_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rso00230]
rso_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rso00230]
rso_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rso00230]
rso_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rso00230]
rso_M00546  Purine degradation, xanthine => urea [PATH:rso00230]
rso_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rso00230]
rso_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rso00230]
Other DBs
GO: 0006163 0042278
Organism
Ralstonia pseudosolanacearum GMI1000 [GN:rso]
Gene
RSc2047  putative nucleoside diphosphate hydrolase protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
RSc0691  putative phosphomannomutase or phosphoglucomutase protein [KO:K15778] [EC:5.4.2.8 5.4.2.2]
RSc0395  prsA; probable ribose-phosphate pyrophosphokinase protein [KO:K00948] [EC:2.7.6.1]
RSc0202  probable ribose-phosphate pyrophosphokinase protein [KO:K00948] [EC:2.7.6.1]
RSc1976  purF; probable amidophosphoribosyltransferase protein [KO:K00764] [EC:2.4.2.14]
RSc2191  purD; probable phosphoribosylamine--glycine ligase (gars) (glycinamideribonucleotide synthetase) (phosphoribosylglycinamide synthetase) protein [KO:K01945] [EC:6.3.4.13]
RSc2454  purN; probable phosphoribosylglycinamide formyltransferase protein [KO:K11175] [EC:2.1.2.2]
RSc1722  purL; probable phosphoribosylformylglycinamidine synthase (fgamsynthase) (fgams) (formylglycinamide ribotide amidotransferase) (fgarat) (formylglycinamide ribotide synthetase) protein [KO:K01952] [EC:6.3.5.3]
RSc2623  purM; probable phosphoribosylformylglycinamidine cyclo-ligase (airs)(phosphoribosyl-aminoimidazole synthetase) (air synthase) protein [KO:K01933] [EC:6.3.3.1]
RSc0576  purK; probable phosphoribosylaminoimidazole carboxylase atpase subunit protein [KO:K01589] [EC:6.3.4.18]
RSc0575  purE; probable phosphoribosylaminoimidazole carboxylase catalytic subunit protein [KO:K01588] [EC:5.4.99.18]
RSc0574  purC; probable phosphoribosylaminoimidazole-succinocarboxamide synthase (saicar synthetase) protein [KO:K01923] [EC:6.3.2.6]
RSc2720  purB; probable adenylosuccinate lyase protein [KO:K01756] [EC:4.3.2.2]
RSc0504  purH; probable bifunctional purine biosynthesis purh [includes:phosphoribosylaminoimidazolecarboxamide formyltransferase (aicar transformylase); imp cyclohydrolase (inosinicase) (imp synthetase) (atic)]. transmembrane protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
RSc0417  apt; probable adenine phosphoribosyltransferase (aprt) protein [KO:K00759] [EC:2.4.2.7]
RSc1204  surE; probable 5'-nucleotidase sure (nucleoside 5'-monophosphatephosphohydrolase) protein [KO:K03787] [EC:3.1.3.5 3.1.3.6]
RSc2552  conserved hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
RSc1629  hypothetical protein of unknown function duf152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
RSc2812  hprT; probable hypoxanthine phosphoribosyltransferase transmembrane protein [KO:K00760] [EC:2.4.2.8]
RSc1429  guaB; probable inosine-5'-monophosphate dehydrogenase oxidoreductase protein [KO:K00088] [EC:1.1.1.205]
RSc1211  ndk; probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein [KO:K00940] [EC:2.7.4.6]
RSc2160  putative xanthosine triphosphate pyrophosphatase protein [KO:K01519] [EC:3.6.1.66]
RSc2095  xdhA; putative xanthine dehydrogenase (subunit a) oxidoreductase protein [KO:K13481] [EC:1.17.1.4]
RSc2096  xdhB; probable xanthine dehydrogenase (subunit b) oxidoreductase protein [KO:K13482] [EC:1.17.1.4]
RSc1158  putative glutamine amidotransferase; protein [KO:K01951] [EC:6.3.5.2]
RSc1431  guaA; probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein [KO:K01951] [EC:6.3.5.2]
RSc0213  putative glutamine amidotransferase protein [KO:K01951] [EC:6.3.5.2]
RSc2099  guaD; probable guanine deaminase (guanine aminohydrolase) (gah) protein [KO:K01487] [EC:3.5.4.3]
RSc2155  gmk; probable guanylate kinase (gmp kinase) protein [KO:K00942] [EC:2.7.4.8]
RSc2805  nrdA; putative ribonucleoside reductase 1 (large chain) oxidoreductase protein [KO:K00525] [EC:1.17.4.1]
RSc0195  probable ribonucleotide reductase, alpha subunit oxidoreductase protein [KO:K00525] [EC:1.17.4.1]
RSc2804  nrdB; putative transmembrane ribonucleoside reductase (small chain) oxidoreductase protein [KO:K00526] [EC:1.17.4.1]
RSp0963  nrdD; putative ribonucleotide reductase oxidoreductase protein [KO:K21636] [EC:1.1.98.6]
RSc2968  dgt; probable deoxyguanosinetriphosphate triphosphohydrolase-like protein. [KO:K01129] [EC:3.1.5.1]
RSc2153  spoT; probable bifunctional enzyme : (p)ppgpp synthetase II and guanosine-3',5'-bisdiphosphate 3'-pyrophosphohydrolase (ppgppase) protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
RSc1537  ppx; probable exopolyphosphatase protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
RSc1576  relA; probable gtp pyrophosphokinase (atp:gtp 3'-pyrophosphotransferase) protein [KO:K00951] [EC:2.7.6.5]
RSc1226  purA; probable adenylosuccinate synthetase (imp--aspartate ligase)(adss) (ampsase) protein [KO:K01939] [EC:6.3.4.4]
RSc2791  probable carbohydrate kinase, pfkb protein [KO:K00856] [EC:2.7.1.20]
RSp0214  amn; probable amp nucleosidase protein [KO:K01241] [EC:3.2.2.4]
RSc2098  add; probable adenosine deaminase (adenosine aminohydrolase) protein [KO:K21053] [EC:3.5.4.2]
RSc3363  cpdB; probable 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor transmembrane protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
RSc2533  adk; probable adenylate kinase (atp-amp transphosphorylase) protein [KO:K00939] [EC:2.7.4.3]
RSp0534  icc; putative cog1409, predicted phosphohydrolases / metallophosphoesterase; protein [KO:K03651] [EC:3.1.4.53]
RSc1795  putative phosphohydrolase or metallophosphoesterase protein [KO:K03651] [EC:3.1.4.53]
RSc0681  apaH; probable bis(5'-nucleosyl)-tetraphosphatase, symmetrical (diadenosine tetraphosphatase) (ap4a hydrolase) (diadenosine 5',5'''-p1,p4-tetraphosphate pyrophosphohydrolase) protein [KO:K01525] [EC:3.6.1.41]
RSc3166  cysC1; probable adenylylsulfate kinase (aps kinase) protein [KO:K00860] [EC:2.7.1.25]
RSp0166  cysC2; probable adenylylsulfate kinase protein [KO:K00860] [EC:2.7.1.25]
RSc2421  cysN; probable sulfate adenylyltransferase subunit 1 protein [KO:K00956] [EC:2.7.7.4]
RSc2422  cysD; putative sulfate adenylyltransferase subunit 2 protein [KO:K00957] [EC:2.7.7.4]
RSc1881  hypothetical transmembrane protein [KO:K22879] [EC:1.14.13.113]
RSc2116  hypothetical transthyretin-like protein [KO:K07127] [EC:3.5.2.17]
RSc2121  conserved hypothetical protein [KO:K13485] [EC:4.1.1.97]
RSc2120  putative predicted xylanase/chitin deacetylase protein [KO:K16842] [EC:3.5.2.5]
RSc3274  alc; probable allantoicase (allantoate amidinohydrolase) protein [KO:K01477] [EC:3.5.3.4]
RSc2032  ureC; probable urease (alpha subunit) protein [KO:K01428] [EC:3.5.1.5]
RSc2033  ureB; probable urease (beta subunit) protein [KO:K01429] [EC:3.5.1.5]
RSc2035  ureA; probable urease gamma subunit (urea amidohydrolase gamma subunit) protein [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rso00030  Pentose phosphate pathway
rso00220  Arginine biosynthesis
rso00250  Alanine, aspartate and glutamate metabolism
rso00260  Glycine, serine and threonine metabolism
rso00340  Histidine metabolism
rso00630  Glyoxylate and dicarboxylate metabolism
rso00730  Thiamine metabolism
rso00740  Riboflavin metabolism
rso00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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