KEGG   PATHWAY: sdul00053
Entry
sdul00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Solanum dulcamara (climbing nightshade)
Class
Metabolism; Carbohydrate metabolism
Pathway map
sdul00053  Ascorbate and aldarate metabolism
sdul00053

Module
sdul_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:sdul00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Solanum dulcamara (climbing nightshade) [GN:sdul]
Gene
129901652  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
129872942  UDP-glucose 6-dehydrogenase 3-like [KO:K00012] [EC:1.1.1.22]
129873155  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
129896512  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
129896951  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
129902203  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
129872284  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
129899474  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
129900302  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
129890568  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
129870384  inositol oxygenase 4-like isoform X1 [KO:K00469] [EC:1.13.99.1]
129881579  LOW QUALITY PROTEIN: aldose reductase [KO:K00002] [EC:1.1.1.2]
129882286  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
129888408  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
129881541  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
129886329  GDP-mannose 3,5-epimerase 1 isoform X1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
129883066  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
129874859  GDP-L-galactose phosphorylase 2-like isoform X1 [KO:K14190] [EC:2.7.7.69]
129898685  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
129870450  inositol monophosphatase 1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
129895996  inositol monophosphatase 3 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
129885429  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
129869928  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
129885678  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
129876073  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
129886690  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
129889909  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
129877603  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
129891594  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
129880759  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
129895422  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
129883056  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
129883297  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
129869902  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
129890096  monodehydroascorbate reductase, chloroplastic/mitochondrial [KO:K08232] [EC:1.6.5.4]
129872339  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
129882116  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
129885322  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
129899031  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
129899346  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
129899501  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
129889136  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
129902454  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
129874749  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
129875023  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
129881041  glutathione S-transferase DHAR1, mitochondrial-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
129896948  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
129885020  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
129885192  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
129887664  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
129904295  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
129891026  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
129881114  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
129885064  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
129889422  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
129880324  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
129894284  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
129874101  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
129874305  glutaredoxin-C3-like [KO:K00128] [EC:1.2.1.3]
129898661  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
129894245  aldehyde dehydrogenase family 7 member B4 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
sdul00020  Citrate cycle (TCA cycle)
sdul00040  Pentose and glucuronate interconversions
sdul00051  Fructose and mannose metabolism
sdul00520  Amino sugar and nucleotide sugar metabolism
sdul00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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