KEGG   PATHWAY: smil00564
Entry
smil00564                   Pathway                                
Name
Glycerophospholipid metabolism - Salvia miltiorrhiza (redroot sage)
Class
Metabolism; Lipid metabolism
Pathway map
smil00564  Glycerophospholipid metabolism
smil00564

Module
smil_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:smil00564]
Other DBs
GO: 0006650
Organism
Salvia miltiorrhiza (redroot sage) [GN:smil]
Gene
130997213  glycerol-3-phosphate dehydrogenase [NAD(+)] 2, chloroplastic isoform X1 [KO:K00006] [EC:1.1.1.8]
130987512  glycerol-3-phosphate dehydrogenase [NAD(+)] [KO:K00006] [EC:1.1.1.8]
131001721  probable glycerol-3-phosphate dehydrogenase [NAD(+)] 1, cytosolic isoform X1 [KO:K00006] [EC:1.1.1.8]
131014818  glycerol-3-phosphate dehydrogenase SDP6, mitochondrial [KO:K00111] [EC:1.1.5.3]
131020869  glycerol-3-phosphate acyltransferase 9 [KO:K13506] [EC:2.3.1.15]
130992741  glycerol-3-phosphate acyltransferase, chloroplastic [KO:K00630] [EC:2.3.1.15]
130985042  glycerol-3-phosphate acyltransferase 1 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131011460  probable glycerol-3-phosphate acyltransferase 8 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
130996767  glycerol-3-phosphate acyltransferase 5-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131016584  glycerol-3-phosphate 2-O-acyltransferase 6-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
130988684  probable glycerol-3-phosphate acyltransferase 2 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131020665  probable glycerol-3-phosphate acyltransferase 8 [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131005900  glycerol-3-phosphate acyltransferase 5-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131022544  glycerol-3-phosphate acyltransferase 1-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
131022618  glycerol-3-phosphate 2-O-acyltransferase 6-like [KO:K13508] [EC:2.3.1.15 2.3.1.198]
130987608  1-acyl-sn-glycerol-3-phosphate acyltransferase BAT2, chloroplastic [KO:K00655] [EC:2.3.1.51]
131014049  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
131014075  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
131002010  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130990130  1-acyl-sn-glycerol-3-phosphate acyltransferase 2-like [KO:K13523] [EC:2.3.1.51 2.3.1.-]
130986554  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 4 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
131005399  probable 1-acyl-sn-glycerol-3-phosphate acyltransferase 5 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
130985084  lysophospholipid acyltransferase 1-like [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
131023697  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
131024367  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
131024684  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
130994668  lysophospholipid acyltransferase 1-like [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
131013993  lysophospholipid acyltransferase 1-like isoform X1 [KO:K13519] [EC:2.3.1.51 2.3.1.23 2.3.1.-]
131001540  triacylglycerol lipase SDP1-like [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
130990189  triacylglycerol lipase SDP1-like [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
131019671  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
131019672  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
131005113  manganese-dependent ADP-ribose/CDP-alcohol diphosphatase-like [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
131010853  uncharacterized protein LOC131010853 isoform X1 [KO:K15728] [EC:3.1.3.4]
130997627  phosphatidate phosphatase PAH1-like [KO:K15728] [EC:3.1.3.4]
131016720  phosphatidate phosphatase PAH1-like [KO:K15728] [EC:3.1.3.4]
131023825  lipid phosphate phosphatase 2-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
131025102  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130986464  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
130986466  lipid phosphate phosphatase 2-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
131020100  lipid phosphate phosphatase 2-like isoform X1 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
131004288  lipid phosphate phosphatase 2-like [KO:K18693] [EC:3.6.1.75 3.1.3.4]
131007681  diacylglycerol kinase 1-like [KO:K00901] [EC:2.7.1.107]
131008644  diacylglycerol kinase 2 [KO:K00901] [EC:2.7.1.107]
131008836  diacylglycerol kinase 1-like [KO:K00901] [EC:2.7.1.107]
131009221  diacylglycerol kinase 5-like [KO:K00901] [EC:2.7.1.107]
131012590  diacylglycerol kinase 5-like [KO:K00901] [EC:2.7.1.107]
130987666  diacylglycerol kinase 4-like [KO:K00901] [EC:2.7.1.107]
131003905  diacylglycerol kinase 3-like [KO:K00901] [EC:2.7.1.107]
131020342  diacylglycerol kinase 1 [KO:K00901] [EC:2.7.1.107]
131024474  non-specific phospholipase C2-like [KO:K01114] [EC:3.1.4.3]
130987802  non-specific phospholipase C6-like [KO:K01114] [EC:3.1.4.3]
131020173  non-specific phospholipase C6 [KO:K01114] [EC:3.1.4.3]
131005334  non-specific phospholipase C6-like [KO:K01114] [EC:3.1.4.3]
130992025  non-specific phospholipase C1 [KO:K01114] [EC:3.1.4.3]
130992295  phospholipase D alpha 1 isoform X1 [KO:K01115] [EC:3.1.4.4]
130993692  phospholipase D delta-like isoform X1 [KO:K01115] [EC:3.1.4.4]
131008906  phospholipase D gamma 1-like [KO:K01115] [EC:3.1.4.4]
130994642  phospholipase D beta 1-like [KO:K01115] [EC:3.1.4.4]
130994651  phospholipase D beta 1-like [KO:K01115] [EC:3.1.4.4]
130994653  phospholipase D beta 1-like [KO:K01115] [EC:3.1.4.4]
130995255  phospholipase D alpha 1-like [KO:K01115] [EC:3.1.4.4]
131026071  phospholipase D beta 1-like [KO:K01115] [EC:3.1.4.4]
131012981  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
130997476  phospholipase D zeta 1-like [KO:K01115] [EC:3.1.4.4]
131001535  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
130988293  phospholipase D alpha 1-like [KO:K01115] [EC:3.1.4.4]
130988862  phospholipase D alpha 1-like [KO:K01115] [EC:3.1.4.4]
131004219  phospholipase D alpha 1 [KO:K01115] [EC:3.1.4.4]
131021004  phospholipase D zeta 1 isoform X1 [KO:K01115] [EC:3.1.4.4]
130991639  phospholipase D alpha 4 [KO:K01115] [EC:3.1.4.4]
130992185  phospholipase D delta-like [KO:K01115] [EC:3.1.4.4]
131021351  phospholipase A2-alpha-like [KO:K01047] [EC:3.1.1.4]
131021364  phospholipase A2-alpha-like [KO:K01047] [EC:3.1.1.4]
131008944  lysophospholipid acyltransferase LPEAT2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
131010436  lysophospholipid acyltransferase LPEAT1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
130986580  lysophospholipid acyltransferase LPEAT1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
131003334  lysophospholipid acyltransferase LPEAT1-like isoform X1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
131023617  phospholipase A(1) DAD1, chloroplastic-like [KO:K16818] [EC:3.1.1.32]
131022817  phospholipase A(1) DAD1, chloroplastic-like [KO:K16818] [EC:3.1.1.32]
131022818  LOW QUALITY PROTEIN: phospholipase A(1) DAD1, chloroplastic-like [KO:K16818] [EC:3.1.1.32]
131013042  lecithin-cholesterol acyltransferase-like 4 [KO:K22389] [EC:3.1.1.32]
131001869  phospholipase A(1) LCAT3 isoform X1 [KO:K22389] [EC:3.1.1.32]
130992337  uncharacterized protein LOC130992337 [KO:K06130] [EC:3.1.1.5]
131024962  acyl-protein thioesterase 1-like isoform X1 [KO:K06130] [EC:3.1.1.5]
131015160  uncharacterized protein LOC131015160 [KO:K06130] [EC:3.1.1.5]
130988868  uncharacterized protein LOC130988868 [KO:K06130] [EC:3.1.1.5]
131004813  uncharacterized protein LOC131004813 [KO:K06130] [EC:3.1.1.5]
130992168  uncharacterized protein LOC130992168 [KO:K06130] [EC:3.1.1.5]
131015995  glycerophosphodiester phosphodiesterase GDPD1, chloroplastic-like [KO:K18696] [EC:3.1.4.46]
131020296  LOW QUALITY PROTEIN: glycerophosphodiester phosphodiesterase GDPD6-like [KO:K01126] [EC:3.1.4.46]
131010965  probable choline kinase 1 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
131026357  probable choline kinase 2 [KO:K14156] [EC:2.7.1.32 2.7.1.82]
131009465  choline-phosphate cytidylyltransferase 2-like isoform X1 [KO:K00968] [EC:2.7.7.15]
131003960  choline-phosphate cytidylyltransferase 2-like [KO:K00968] [EC:2.7.7.15]
131015035  choline/ethanolaminephosphotransferase 1-like [KO:K00993] [EC:2.7.8.1]
130986297  choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K00993] [EC:2.7.8.1]
131011707  serine decarboxylase-like isoform X1 [KO:K25193] [EC:4.1.1.-]
131011710  serine decarboxylase-like isoform X1 [KO:K25193] [EC:4.1.1.-]
131020485  probable ethanolamine kinase isoform X1 [KO:K00894] [EC:2.7.1.82]
131016407  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
130988690  ethanolamine-phosphate cytidylyltransferase-like isoform X1 [KO:K00967] [EC:2.7.7.14]
131003725  ethanolamine-phosphate cytidylyltransferase-like [KO:K00967] [EC:2.7.7.14]
130990261  phosphoethanolamine N-methyltransferase 1-like [KO:K05929] [EC:2.1.1.103]
130990262  phosphoethanolamine N-methyltransferase 1-like [KO:K05929] [EC:2.1.1.103]
131005054  phosphatidyl-N-methylethanolamine N-methyltransferase [KO:K00550] [EC:2.1.1.71]
130986245  phosphatidate cytidylyltransferase 3-like isoform X1 [KO:K00981] [EC:2.7.7.41]
131001098  phosphatidate cytidylyltransferase 1-like [KO:K00981] [EC:2.7.7.41]
130991298  phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
131022014  phosphatidate cytidylyltransferase 4, chloroplastic-like isoform X1 [KO:K00981] [EC:2.7.7.41]
131025112  LOW QUALITY PROTEIN: CDP-diacylglycerol--serine O-phosphatidyltransferase 1 [KO:K08730] [EC:2.7.8.29]
131019415  phosphatidylserine decarboxylase proenzyme 2-like isoform X1 [KO:K01613] [EC:4.1.1.65]
131004351  phosphatidylserine decarboxylase proenzyme 1, mitochondrial [KO:K01613] [EC:4.1.1.65]
131014932  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2-like [KO:K00995] [EC:2.7.8.5]
131001939  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2-like isoform X1 [KO:K00995] [EC:2.7.8.5]
131009079  phosphatidylglycerophosphate phosphatase 1, chloroplastic/mitochondrial-like isoform X1 [KO:K01094] [EC:3.1.3.27]
131012236  phosphatidylglycerophosphate phosphatase 1, chloroplastic/mitochondrial-like [KO:K01094] [EC:3.1.3.27]
130985764  cardiolipin synthase (CMP-forming), mitochondrial [KO:K08744] [EC:2.7.8.41]
131022201  CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1, chloroplastic-like isoform X1 [KO:K08744] [EC:2.7.8.41]
131023763  N-acylphosphatidylethanolamine synthase isoform X1 [KO:K13511] [EC:2.3.1.-]
130996864  uncharacterized protein LOC130996864 [KO:K13511] [EC:2.3.1.-]
130996865  uncharacterized protein LOC130996865 [KO:K13511] [EC:2.3.1.-]
131001676  probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2 [KO:K00999] [EC:2.7.8.11]
131022078  probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2 [KO:K00999] [EC:2.7.8.11]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
smil00010  Glycolysis / Gluconeogenesis
smil00260  Glycine, serine and threonine metabolism
smil00561  Glycerolipid metabolism
smil00562  Inositol phosphate metabolism
smil00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
smil00565  Ether lipid metabolism
smil00620  Pyruvate metabolism
KO pathway
ko00564   
LinkDB

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