KEGG   PATHWAY: snk00230
Entry
snk00230                    Pathway                                
Name
Purine metabolism - Streptomyces nitrosporeus
Class
Metabolism; Nucleotide metabolism
Pathway map
snk00230  Purine metabolism
snk00230

Module
snk_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:snk00230]
snk_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:snk00230]
snk_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:snk00230]
snk_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:snk00230]
snk_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:snk00230]
snk_M00546  Purine degradation, xanthine => urea [PATH:snk00230]
snk_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:snk00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces nitrosporeus [GN:snk]
Gene
CP967_32460  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
CP967_20440  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
CP967_16180  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CP967_16285  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CP967_12860  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CP967_16215  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
CP967_16225  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
CP967_16220  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
CP967_16175  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CP967_20880  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CP967_20885  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CP967_16270  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CP967_30225  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CP967_12855  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CP967_28895  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CP967_15710  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CP967_22030  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
CP967_12250  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CP967_25660  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CP967_18975  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CP967_13045  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
CP967_13050  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CP967_23200  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CP967_21780  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
CP967_32540  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
CP967_32535  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
CP967_32530  (2Fe-2S)-binding protein [KO:K13483]
CP967_12990  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
CP967_29120  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
CP967_29065  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CP967_07645  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
CP967_10885  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CP967_10890  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
CP967_23725  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CP967_28900  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CP967_07700  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CP967_19190  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CP967_20610  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CP967_03735  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CP967_12195  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CP967_18295  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CP967_29415  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CP967_25285  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CP967_12325  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP967_13670  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP967_15835  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CP967_23530  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CP967_26050  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
CP967_13260  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CP967_28815  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
CP967_29355  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CP967_05395  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CP967_29345  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CP967_05405  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CP967_29350  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CP967_05400  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CP967_04940  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
CP967_04945  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CP967_04950  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CP967_12690  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CP967_04785  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
CP967_23000  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
CP967_30370  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CP967_05075  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CP967_26270  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CP967_30365  urease subunit beta [KO:K01429] [EC:3.5.1.5]
CP967_05080  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
CP967_30360  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
CP967_05085  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
CP967_26255  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
snk00030  Pentose phosphate pathway
snk00220  Arginine biosynthesis
snk00250  Alanine, aspartate and glutamate metabolism
snk00260  Glycine, serine and threonine metabolism
snk00340  Histidine metabolism
snk00630  Glyoxylate and dicarboxylate metabolism
snk00730  Thiamine metabolism
snk00740  Riboflavin metabolism
snk00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system