KEGG   PATHWAY: sstn00053
Entry
sstn00053                   Pathway                                
Name
Ascorbate and aldarate metabolism - Solanum stenotomum
Class
Metabolism; Carbohydrate metabolism
Pathway map
sstn00053  Ascorbate and aldarate metabolism
sstn00053

Module
sstn_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:sstn00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Solanum stenotomum [GN:sstn]
Gene
125875214  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
125860402  UDP-glucose 6-dehydrogenase 5-like [KO:K00012] [EC:1.1.1.22]
125846487  UDP-glucose 6-dehydrogenase 2 [KO:K00012] [EC:1.1.1.22]
125847067  UDP-glucose 6-dehydrogenase 3 [KO:K00012] [EC:1.1.1.22]
125849909  UDP-sugar pyrophosphorylase [KO:K12447] [EC:2.7.7.64]
125848908  glucuronokinase 1 [KO:K16190] [EC:2.7.1.43]
125863279  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
125851631  probable inositol oxygenase [KO:K00469] [EC:1.13.99.1]
125865912  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
125873121  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
125861925  inositol oxygenase 4-like [KO:K00469] [EC:1.13.99.1]
125850507  aldo-keto reductase family 4 member C10-like [KO:K00002] [EC:1.1.1.2]
125871459  LOW QUALITY PROTEIN: aldose reductase [KO:K00002] [EC:1.1.1.2]
125851474  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
125854735  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
125856139  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
125870734  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
125843268  L-gulonolactone oxidase 3 [KO:K00103] [EC:1.1.3.8]
125869350  GDP-mannose 3,5-epimerase 1 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
125870680  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
125872540  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
125846607  GDP-L-galactose phosphorylase 2-like [KO:K14190] [EC:2.7.7.69]
125856926  inositol monophosphatase 1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
125860054  inositol monophosphatase 2 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
125844882  inositol monophosphatase 3 isoform X1 [KO:K10047] [EC:3.1.3.25 3.1.3.93]
125856179  bifunctional phosphatase IMPL2, chloroplastic-like [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
125873217  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
125844747  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
125866344  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
125863037  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
125876052  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
125850358  UDP-glucuronate 4-epimerase 1-like [KO:K08679] [EC:5.1.3.6]
125865233  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
125878420  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
125851133  UDP-glucuronate 4-epimerase 5-like [KO:K08679] [EC:5.1.3.6]
125852801  UDP-glucuronate 4-epimerase 2 [KO:K08679] [EC:5.1.3.6]
125866638  UDP-glucuronate 4-epimerase 6-like [KO:K08679] [EC:5.1.3.6]
125867659  UDP-glucuronate 4-epimerase 3-like [KO:K08679] [EC:5.1.3.6]
125870635  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
125860844  UDP-glucuronate 4-epimerase 2-like [KO:K08679] [EC:5.1.3.6]
125856242  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
125856604  D-galacturonate reductase-like [KO:K19642] [EC:1.1.1.365]
125847555  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
125870593  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
125841835  monodehydroascorbate reductase, chloroplastic/mitochondrial [KO:K08232] [EC:1.6.5.4]
125849001  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
125849502  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
125878176  putative L-ascorbate peroxidase 6 [KO:K00434] [EC:1.11.1.11]
125867429  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
125871593  L-ascorbate peroxidase 2, cytosolic [KO:K00434] [EC:1.11.1.11]
125872555  L-ascorbate peroxidase 1, cytosolic [KO:K00434] [EC:1.11.1.11]
125845069  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
125874359  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial [KO:K00434] [EC:1.11.1.11]
125874399  L-ascorbate peroxidase 1, cytosolic-like [KO:K00434] [EC:1.11.1.11]
125867684  glutathione S-transferase DHAR2-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
125843897  glutathione S-transferase DHAR3, chloroplastic [KO:K21888] [EC:1.8.5.1 2.5.1.18]
125850802  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125853317  L-ascorbate oxidase-like isoform X1 [KO:K00423] [EC:1.10.3.3]
125867539  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125867701  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125869410  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125841479  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125857498  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125844170  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
125844399  L-ascorbate oxidase [KO:K00423] [EC:1.10.3.3]
125849554  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
125849557  glutaredoxin-C3-like [KO:K00128] [EC:1.2.1.3]
125841532  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
125860154  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
125873135  aldehyde dehydrogenase [KO:K00128] [EC:1.2.1.3]
125860893  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
125874180  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
125857478  aldehyde dehydrogenase family 7 member B4 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
sstn00020  Citrate cycle (TCA cycle)
sstn00040  Pentose and glucuronate interconversions
sstn00051  Fructose and mannose metabolism
sstn00520  Amino sugar and nucleotide sugar metabolism
sstn00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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