KEGG   PATHWAY: xbo00230
Entry
xbo00230                    Pathway                                
Name
Purine metabolism - Xenorhabdus bovienii SS-2004
Class
Metabolism; Nucleotide metabolism
Pathway map
xbo00230  Purine metabolism
xbo00230

Module
xbo_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:xbo00230]
xbo_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:xbo00230]
xbo_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:xbo00230]
xbo_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:xbo00230]
xbo_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:xbo00230]
Other DBs
GO: 0006163 0042278
Organism
Xenorhabdus bovienii SS-2004 [GN:xbo]
Gene
XBJ1_1813  nudF; adenosine diphosphate sugar pyrophosphatase (ADP-ribose pyrophosphatase) [KO:K01515] [EC:3.6.1.13 3.6.1.-]
XBJ1_0067  Nudix hydrolase, active on adenosine(5')triphospho(5')adenosine, adenosine(5')diphospho(5')adenosine, ADP-ribose and NADH (fragment) [KO:K08312] [EC:3.6.1.-]
XBJ1_3540  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
XBJ1_1074  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
XBJ1_2198  prs; phosphoribosylpyrophosphate synthetase [KO:K00948] [EC:2.7.6.1]
XBJ1_2959  purF; amidophosphoribosyltransferase (PRPP amidotransferase) [KO:K00764] [EC:2.4.2.14]
XBJ1_4019  purD; phosphoribosylglycinamide synthetase (GAR synthetase) [KO:K01945] [EC:6.3.4.13]
XBJ1_2072  purN; phosphoribosylglycinamide formyltransferase 1 [KO:K11175] [EC:2.1.2.2]
XBJ1_3040  purL; phosphoribosylformyl-glycineamide synthetase (FGAM synthetase) [KO:K01952] [EC:6.3.5.3]
XBJ1_2073  purM; phosphoribosylaminoimidazole synthetase (AIR synthetase) [KO:K01933] [EC:6.3.3.1]
XBJ1_3097  purK; phosphoribosylaminoimidazole carboxylase = AIR carboxylase, CO(2)-fixing subunit [KO:K01589] [EC:6.3.4.18]
XBJ1_3096  purE; phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
XBJ1_2632  purC; phosphoribosylaminoimidazole-succinocarboxamide synthetase (SAICAR synthetase) [KO:K01923] [EC:6.3.2.6]
XBJ1_2833  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
XBJ1_4018  purH; bifunctional: IMP cyclohydrolase (N-terminal); phosphoribosylaminoimidazolecarboxamide formyltransferase (C-terminal) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
XBJ1_1612  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
XBJ1_1598  ushA; bifunctional: UDP-sugar hydrolase; 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
XBJ1_3584  surE; survival protein, protein damage control [KO:K03787] [EC:3.1.3.5 3.1.3.6]
XBJ1_1602  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
XBJ1_3539  deoD; purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
XBJ1_3258  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
XBJ1_3558  rihB; ribonucleoside hydrolase 2, pyrimidine-specific, silent [KO:K25589] [EC:3.2.2.2 3.2.2.3]
XBJ1_3682  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
XBJ1_2584  guaB; IMP dehydrogeanse [KO:K00088] [EC:1.1.1.205]
XBJ1_3013  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
XBJ1_3522  conserved hypothetical protein [KO:K01529] [EC:3.6.1.73]
XBJ1_3345  putative protein controls HAP (6-N-hydroxylaminopurine) mutagenesis (Ham1) [KO:K01519] [EC:3.6.1.66]
XBJ1_3299  gpt; guanine-hypoxanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
XBJ1_2583  guaA; GMP synthetase (glutamine aminotransferase) [KO:K01951] [EC:6.3.5.2]
XBJ1_0235  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
XBJ1_0728  nrdA; ribonucleoside diphosphate reductase 1, alpha subunit [KO:K00525] [EC:1.17.4.1]
XBJ1_0727  nrdB; ribonucleoside-diphosphate reductase 1, beta subunit [KO:K00526] [EC:1.17.4.1]
XBJ1_3657  dgt; deoxyguanosine triphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
XBJ1_2930  putative 5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
XBJ1_0233  spoT; bifunctional: (p)ppGpp synthetase II; guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
XBJ1_4185  gpp; guanosine pentaphosphatase, also has exopolyphosphatase activity [KO:K01524] [EC:3.6.1.11 3.6.1.40]
XBJ1_2068  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
XBJ1_3654  relA; (p)ppGpp synthetase I (GTP pyrophosphokinase) [KO:K00951] [EC:2.7.6.5]
XBJ1_4158  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
XBJ1_0325  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
XBJ1_2313  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
XBJ1_0577  conserved hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
XBJ1_1698  cpdB; 2':3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
XBJ1_1605  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
XBJ1_3653  Protein mazG [KO:K04765] [EC:3.6.1.9]
XBJ1_1812  cpdA; cyclic 3',5'-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
XBJ1_0953  hypothetical protein [KO:K03651] [EC:3.1.4.53]
XBJ1_1804  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
XBJ1_3606  cysC; adenosine 5'-phosphosulfate kinase [KO:K00860] [EC:2.7.1.25]
XBJ1_3607  cysN; ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase) [KO:K00956] [EC:2.7.7.4]
XBJ1_3608  cysD; ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase) [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
xbo00030  Pentose phosphate pathway
xbo00220  Arginine biosynthesis
xbo00250  Alanine, aspartate and glutamate metabolism
xbo00260  Glycine, serine and threonine metabolism
xbo00340  Histidine metabolism
xbo00630  Glyoxylate and dicarboxylate metabolism
xbo00730  Thiamine metabolism
xbo00740  Riboflavin metabolism
xbo00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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