KEGG   PATHWAY: pbi00330
Entry
pbi00330                    Pathway                                
Name
Arginine and proline metabolism - Python bivittatus (Burmese python)
Class
Metabolism; Amino acid metabolism
Pathway map
pbi00330  Arginine and proline metabolism
pbi00330

Module
pbi_M00015  Proline biosynthesis, glutamate => proline [PATH:pbi00330]
pbi_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:pbi00330]
pbi_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:pbi00330]
pbi_M00970  Proline degradation, proline => glutamate [PATH:pbi00330]
pbi_M00972  Proline metabolism [PATH:pbi00330]
Other DBs
GO: 0006525 0006560
Organism
Python bivittatus (Burmese python) [GN:pbi]
Gene
103048409  ALDH4A1; delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
103049310  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
103049565  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase isoform X1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
103049999  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
103050194  [KO:K00274] [EC:1.4.3.4]
103051066  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
103051894  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
103052669  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
103052717  PYCR3; pyrroline-5-carboxylate reductase 3 [KO:K00286] [EC:1.5.1.2]
103052732  SMOX; spermine oxidase [KO:K12259] [EC:1.5.3.16 1.5.3.-]
103052866  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
103052972  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
103053263  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
103053532  [KO:K00318] [EC:1.5.5.2]
103053662  [KO:K11142] [EC:3.4.11.1 3.4.11.5]
103055918  ALDH16A1; aldehyde dehydrogenase family 16 member A1 isoform X3 [KO:K00128] [EC:1.2.1.3]
103056447  PRODH2; hydroxyproline dehydrogenase isoform X1 [KO:K11394] [EC:1.5.5.3]
103056766  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
103056887  SATL1; spermidine/spermine N(1)-acetyltransferase-like protein 1 [KO:K00657] [EC:2.3.1.57]
103056986  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase isoform X1 [KO:K00149] [EC:1.2.1.47 1.2.1.3]
103057026  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
103059559  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
103059727  AGMAT; agmatinase, mitochondrial [KO:K27001]
103059803  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
103060339  ARG2; arginase-2, mitochondrial isoform X1 [KO:K01476] [EC:3.5.3.1]
103060423  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
103060833  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
103061601  [KO:K00657] [EC:2.3.1.57]
103061725  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
103061734  ALDH3A2; fatty aldehyde dehydrogenase isoform X2 [KO:K00128] [EC:1.2.1.3]
103061823  [KO:K00657] [EC:2.3.1.57]
103061945  [KO:K00657] [EC:2.3.1.57]
103061946  [KO:K00274] [EC:1.4.3.4]
103062106  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
103062242  [KO:K00933] [EC:2.7.3.2]
103062673  [KO:K00657] [EC:2.3.1.57]
103062784  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
103063211  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
103063558  ARG1; LOW QUALITY PROTEIN: arginase-1 [KO:K01476] [EC:3.5.3.1]
103063653  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
103064593  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
103065136  [KO:K13242] [EC:1.14.13.39]
103065664  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
103065920  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
103066152  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
103066504  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
103066739  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
103066775  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
103067547  CKM; creatine kinase M-type [KO:K27382]
103068026  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
pbi00020  Citrate cycle (TCA cycle)
pbi00220  Arginine biosynthesis
pbi00250  Alanine, aspartate and glutamate metabolism
pbi00260  Glycine, serine and threonine metabolism
pbi00270  Cysteine and methionine metabolism
pbi00310  Lysine degradation
pbi00410  beta-Alanine metabolism
pbi00470  D-Amino acid metabolism
pbi00480  Glutathione metabolism
pbi00630  Glyoxylate and dicarboxylate metabolism
pbi00650  Butanoate metabolism
pbi00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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