KEGG   PATHWAY: pcoq00330
Entry
pcoq00330                   Pathway                                
Name
Arginine and proline metabolism - Propithecus coquereli (Coquerel's sifaka)
Class
Metabolism; Amino acid metabolism
Pathway map
pcoq00330  Arginine and proline metabolism
pcoq00330

Module
pcoq_M00015  Proline biosynthesis, glutamate => proline [PATH:pcoq00330]
pcoq_M00047  Creatine pathway [PATH:pcoq00330]
pcoq_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:pcoq00330]
pcoq_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:pcoq00330]
pcoq_M00972  Proline metabolism [PATH:pcoq00330]
Other DBs
GO: 0006525 0006560
Organism
Propithecus coquereli (Coquerel's sifaka) [GN:pcoq]
Gene
105805413  ALDH1B1; aldehyde dehydrogenase X, mitochondrial [KO:K00128] [EC:1.2.1.3]
105805546  LAP3; cytosol aminopeptidase [KO:K11142] [EC:3.4.11.1 3.4.11.5]
105806211  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
105806446  ALDH9A1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
105808558  AZIN2; antizyme inhibitor 2 isoform X1 [KO:K01583] [EC:4.1.1.19]
105808659  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
105809033  MAOB; amine oxidase [flavin-containing] B [KO:K00274] [EC:1.4.3.4]
105809065  MAOA; amine oxidase [flavin-containing] A [KO:K00274] [EC:1.4.3.4]
105810407  PYCR2; pyrroline-5-carboxylate reductase 2 [KO:K00286] [EC:1.5.1.2]
105811288  GAMT; guanidinoacetate N-methyltransferase isoform X1 [KO:K00542] [EC:2.1.1.2]
105811412  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
105812604  CKB; creatine kinase B-type [KO:K00933] [EC:2.7.3.2]
105813200  GOT2; aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
105813446  PYCRL; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
105813504  NOS2; nitric oxide synthase, inducible [KO:K13241] [EC:1.14.13.39]
105814010  CNDP1; beta-Ala-His dipeptidase [KO:K05604] [EC:3.4.13.20]
105814014  CNDP2; cytosolic non-specific dipeptidase [KO:K08660] [EC:3.4.13.18]
105814031  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
105814396  [KO:K00933] [EC:2.7.3.2]
105814457  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
105815845  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
105815919  AMD1; S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
105816104  ALDH3A2; fatty aldehyde dehydrogenase isoform X1 [KO:K00128] [EC:1.2.1.3]
105816146  PRODH2; probable proline dehydrogenase 2 isoform X1 [KO:K11394] [EC:1.5.5.3]
105817664  CKM; creatine kinase M-type [KO:K27382]
105818486  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
105818494  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
105818856  [KO:K00318] [EC:1.5.5.2]
105819398  SAT2; diamine acetyltransferase 2 [KO:K00657] [EC:2.3.1.57]
105819499  [KO:K01581] [EC:4.1.1.17]
105819840  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
105819931  L3HYPDH; trans-3-hydroxy-L-proline dehydratase [KO:K18384] [EC:4.2.1.77]
105819970  SAT1; diamine acetyltransferase 1 [KO:K00657] [EC:2.3.1.57]
105819977  SMS; spermine synthase [KO:K00802] [EC:2.5.1.22]
105820031  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial [KO:K00286] [EC:1.5.1.2]
105821021  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
105824306  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
105824630  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
105824632  NOS3; nitric oxide synthase, endothelial [KO:K13242] [EC:1.14.13.39]
105824869  AGMAT; agmatinase, mitochondrial [KO:K27001]
105824942  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
105825189  NOS1; nitric oxide synthase, brain [KO:K13240] [EC:1.14.13.39]
105825441  P4HA1; prolyl 4-hydroxylase subunit alpha-1 [KO:K00472] [EC:1.14.11.2]
105825631  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
105826344  ALDH7A1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
105826533  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
105827149  ARG1; arginase-1 [KO:K01476] [EC:3.5.3.1]
105827361  CARNS1; carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
pcoq00020  Citrate cycle (TCA cycle)
pcoq00220  Arginine biosynthesis
pcoq00250  Alanine, aspartate and glutamate metabolism
pcoq00260  Glycine, serine and threonine metabolism
pcoq00270  Cysteine and methionine metabolism
pcoq00310  Lysine degradation
pcoq00410  beta-Alanine metabolism
pcoq00470  D-Amino acid metabolism
pcoq00480  Glutathione metabolism
pcoq00630  Glyoxylate and dicarboxylate metabolism
pcoq00650  Butanoate metabolism
pcoq00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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