KEGG   PATHWAY: rko00230
Entry
rko00230                    Pathway                                
Name
Purine metabolism - Rhodococcus koreensis
Class
Metabolism; Nucleotide metabolism
Pathway map
rko00230  Purine metabolism
rko00230

Module
rko_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:rko00230]
rko_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:rko00230]
rko_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:rko00230]
rko_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:rko00230]
rko_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:rko00230]
rko_M00546  Purine degradation, xanthine => urea [PATH:rko00230]
rko_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:rko00230]
rko_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:rko00230]
Other DBs
GO: 0006163 0042278
Organism
Rhodococcus koreensis [GN:rko]
Gene
JWS14_34815  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
JWS14_31320  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
JWS14_26785  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
JWS14_26395  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
JWS14_30590  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
JWS14_11705  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
JWS14_26760  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
JWS14_26720  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
JWS14_26725  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
JWS14_26790  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
JWS14_34270  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
JWS14_34275  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
JWS14_26575  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
JWS14_26450  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
JWS14_30595  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
JWS14_37170  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
JWS14_22520  5'-nucleotidase C-terminal domain-containing protein [KO:K01081] [EC:3.1.3.5]
JWS14_14590  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
JWS14_20760  5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
JWS14_11650  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
JWS14_34050  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
JWS14_05635  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
JWS14_37870  nucleoside hydrolase [KO:K01239] [EC:3.2.2.1]
JWS14_23815  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
JWS14_33755  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
JWS14_33760  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
JWS14_06800  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
JWS14_07365  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
JWS14_01320  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
JWS14_01315  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
JWS14_01310  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
JWS14_33770  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
JWS14_37910  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
JWS14_20840  amidohydrolase family protein [KO:K01487] [EC:3.5.4.3]
JWS14_37455  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
JWS14_34950  nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
JWS14_33835  R2-like ligand-binding oxidase [KO:K00526] [EC:1.17.4.1]
JWS14_34955  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
JWS14_38260  nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
JWS14_06300  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
JWS14_37175  RelA/SpoT family protein [KO:K01139] [EC:2.7.6.5 3.1.7.2]
JWS14_10550  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
JWS14_31615  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
JWS14_09945  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
JWS14_11410  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
JWS14_27965  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
JWS14_28335  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
JWS14_30400  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
JWS14_44950  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
JWS14_05915  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
JWS14_34005  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
JWS14_32890  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
JWS14_25030  adenylate kinase [KO:K00939] [EC:2.7.4.3]
JWS14_33495  adenylate kinase [KO:K00939] [EC:2.7.4.3]
JWS14_44855  adenylate kinase [KO:K00939] [EC:2.7.4.3]
JWS14_31520  MazG family protein [KO:K04765] [EC:3.6.1.9]
JWS14_36040  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
JWS14_08495  phosphodiesterase [KO:K03651] [EC:3.1.4.53]
JWS14_37070  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
JWS14_06555  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
JWS14_07800  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
JWS14_06495  50S ribosome-binding GTPase [KO:K00956] [EC:2.7.7.4]
JWS14_06490  sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
JWS14_06550  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
JWS14_07805  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
JWS14_24360  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
JWS14_08055  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
JWS14_24365  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
JWS14_08050  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
JWS14_24370  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
JWS14_30460  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
JWS14_08045  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
JWS14_13470  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
JWS14_24375  aspartate/glutamate racemase family protein [KO:K16841] [EC:5.1.99.3]
JWS14_13480  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
JWS14_24390  puuE; allantoinase PuuE [KO:K16842] [EC:3.5.2.5]
JWS14_13490  allantoicase [KO:K01477] [EC:3.5.3.4]
JWS14_24395  allantoicase [KO:K01477] [EC:3.5.3.4]
JWS14_31075  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
JWS14_31070  urease subunit beta [KO:K01429] [EC:3.5.1.5]
JWS14_31065  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
rko00030  Pentose phosphate pathway
rko00220  Arginine biosynthesis
rko00250  Alanine, aspartate and glutamate metabolism
rko00260  Glycine, serine and threonine metabolism
rko00340  Histidine metabolism
rko00630  Glyoxylate and dicarboxylate metabolism
rko00730  Thiamine metabolism
rko00740  Riboflavin metabolism
rko00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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