KEGG   PATHWAY: rno00561
Entry
rno00561                    Pathway                                
Name
Glycerolipid metabolism - Rattus norvegicus (rat)
Class
Metabolism; Lipid metabolism
Pathway map
rno00561  Glycerolipid metabolism
rno00561

Module
rno_M00089  Triacylglycerol biosynthesis [PATH:rno00561]
rno_M00098  Acylglycerol degradation [PATH:rno00561]
Other DBs
GO: 0046486
Organism
Rattus norvegicus (rat) [GN:rno]
Gene
684314  Glyctk; glycerate kinase [KO:K11529] [EC:2.7.1.165]
29539  Aldh2; aldehyde dehydrogenase, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
65183  Aldh3a2; aldehyde dehydrogenase family 3 member A2 [KO:K00128] [EC:1.2.1.3]
298079  Aldh1b1; aldehyde dehydrogenase X, mitochondrial precursor [KO:K00128] [EC:1.2.1.3]
291450  Aldh7a1; alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
64040  Aldh9a1; 4-trimethylaminobutyraldehyde dehydrogenase [KO:K00149] [EC:1.2.1.47 1.2.1.3]
24192  Akr1b1; aldo-keto reductase family 1 member B1 [KO:K00011] [EC:1.1.1.21]
116463  Akr1b7; aldo-keto reductase family 1 member B7 [KO:K00011] [EC:1.1.1.21]
286921  Akr1b8; aldose reductase-related protein 2 [KO:K00011] [EC:1.1.1.21]
296972  Akr1b10; aldo-keto reductase family 1 member B10 [KO:K00011] [EC:1.1.1.21]
78959  Akr1a1; aldo-keto reductase family 1 member A1 [KO:K00002] [EC:1.1.1.2]
361730  Tkfc; triokinase/FMN cyclase [KO:K00863] [EC:2.7.1.28 2.7.1.29 4.6.1.15]
79223  Gk; glycerol kinase [KO:K00864] [EC:2.7.1.30]
289481  Gk2; glycerol kinase 2 [KO:K00864] [EC:2.7.1.30]
291468  Gykl1; glycerol kinase-like 1 [KO:K00864] [EC:2.7.1.30]
29653  Gpam; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
296130  Gpat2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
290843  Gpat4; glycerol-3-phosphate acyltransferase 6 [KO:K13506] [EC:2.3.1.15]
305166  Gpat3; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
406165  Agpat1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
311821  Agpat2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta precursor [KO:K13509] [EC:2.3.1.51]
294324  Agpat3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
170919  Agpat4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
306582  Agpat5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon isoform 1 [KO:K19007] [EC:2.3.1.51]
362702  Lclat1; lysocardiolipin acyltransferase 1 isoform X1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
498741  Mboat1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
313997  Mboat2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
64369  Plpp1; phospholipid phosphatase 1 [KO:K01080] [EC:3.1.3.4]
246115  Plpp2; phospholipid phosphatase 2 [KO:K01080] [EC:3.1.3.4]
192270  Plpp3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
313977  Lpin1; phosphatidate phosphatase LPIN1 [KO:K15728] [EC:3.1.3.4]
362261  Lpin3; phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
316737  Lpin2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
680466  Plpp5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
309014  Plpp4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
81821  Dgkz; diacylglycerol kinase zeta isoform 2 [KO:K00901] [EC:2.7.1.107]
25666  Dgkg; diacylglycerol kinase gamma [KO:K00901] [EC:2.7.1.107]
54248  Dgkb; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
140866  Dgka; diacylglycerol kinase alpha [KO:K00901] [EC:2.7.1.107]
688705  Dgki; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
361076  Dgkh; diacylglycerol kinase eta isoform X4 [KO:K00901] [EC:2.7.1.107]
368088  Dgkd; diacylglycerol kinase delta isoform X2 [KO:K00901] [EC:2.7.1.107]
100361138  Dgkq; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
367745  Dgkk; diacylglycerol kinase kappa isoform X1 [KO:K00901] [EC:2.7.1.107]
497978  Dgke; diacylglycerol kinase epsilon isoform 1 [KO:K00901] [EC:2.7.1.107]
84497  Dgat1; diacylglycerol O-acyltransferase 1 [KO:K11155] [EC:2.3.1.20 2.3.1.75 2.3.1.76]
252900  Dgat2; diacylglycerol O-acyltransferase 2 [KO:K11160] [EC:2.3.1.20 2.3.1.75]
24254  Cel; bile salt-activated lipase precursor [KO:K12298] [EC:3.1.1.13 3.1.1.3]
361676  Pnpla2; patatin-like phospholipase domain-containing protein 2 [KO:K16816] [EC:3.1.1.3]
362972  Pnpla3; 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 [KO:K13534] [EC:3.1.1.3 2.3.1.-]
25702  Pnlip; pancreatic triacylglycerol lipase precursor [KO:K14073] [EC:3.1.1.3]
84028  Pnliprp1; inactive pancreatic lipase-related protein 1 precursor [KO:K14074] [EC:3.1.1.3]
117554  Pnliprp2; pancreatic lipase-related protein 2 precursor [KO:K14075] [EC:3.1.1.3]
24538  Lipc; hepatic triacylglycerol lipase precursor [KO:K22283] [EC:3.1.1.3]
50682  Lipf; gastric triacylglycerol lipase precursor [KO:K14452] [EC:3.1.1.3]
291437  Lipg; endothelial lipase precursor [KO:K22284] [EC:3.1.1.3]
24539  Lpl; lipoprotein lipase precursor [KO:K01059] [EC:3.1.1.34]
502749  Agk; acylglycerol kinase, mitochondrial [KO:K09881] [EC:2.7.1.94]
29254  Mgll; monoglyceride lipase isoform 2 [KO:K01054] [EC:3.1.1.23]
361796  Abhd16a; phosphatidylserine lipase ABHD16A [KO:K25824] [EC:3.1.1.23 3.1.-.-]
363261  Mogat1; 2-acylglycerol O-acyltransferase 1 [KO:K14458] [EC:2.3.1.22]
681211  Mogat2; 2-acylglycerol O-acyltransferase 2 [KO:K14457] [EC:2.3.1.22]
363494  Gla; alpha-galactosidase A [KO:K01189] [EC:3.2.1.22]
Compound
C00029  UDP-glucose
C00040  Acyl-CoA
C00093  sn-Glycerol 3-phosphate
C00103  D-Glucose 1-phosphate
C00111  Glycerone phosphate
C00116  Glycerol
C00162  Fatty acid
C00173  Acyl-[acyl-carrier protein]
C00184  Glycerone
C00197  3-Phospho-D-glycerate
C00258  D-Glycerate
C00416  Phosphatidate
C00422  Triacylglycerol
C00577  D-Glyceraldehyde
C00631  2-Phospho-D-glycerate
C00641  1,2-Diacyl-sn-glycerol
C00681  1-Acyl-sn-glycerol 3-phosphate
C00969  3-Hydroxypropanal
C01885  1-Acylglycerol
C02133  Acyl phosphate
C02457  Propane-1,3-diol
C03692  1,2-Diacyl-3-beta-D-galactosyl-sn-glycerol
C04046  3-D-Glucosyl-1,2-diacylglycerol
C04315  2-Acyl-3-O-(beta-D-galactosyl)-sn-glycerol
C04872  1,2-Diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol
C05401  3-beta-D-Galactosyl-sn-glycerol
C06037  Digalactosyl-diacylglycerol
C06038  Acyl1-monogalactosyl-diacylglycerol
C06040  Diglucosyldiacylglycerol
C06041  Glycerophosphoglycoglycerolipid
C06042  Lipoteichoic acid
C06364  1,2-Diacyl-3-alpha-D-glucosyl-sn-glycerol
C06365  alpha-Kojibiosyldiacylglycerol
C11521  UDP-6-sulfoquinovose
C13508  Sulfoquinovosyldiacylglycerol
C20897  Glycerophosphoglycoglycerolipid
C20898  Lipoteichoic acid
C20991  1,2-Diacyl-3-O-[beta-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol
Reference
PMID:8662716
  Authors
Norbeck J, Pahlman AK, Akhtar N, Blomberg A, Adler L.
  Title
Purification and characterization of two isoenzymes of DL-glycerol-3-phosphatase from Saccharomyces cerevisiae. Identification of the corresponding GPP1 and GPP2 genes and evidence for osmotic regulation of Gpp2p expression by the osmosensing mitogen-activated protein kinase signal transduction pathway.
  Journal
J Biol Chem 271:13875-81 (1996)
DOI:10.1074/jbc.271.23.13875
Reference
PMID:8995384
  Authors
Karlsson OP, Dahlqvist A, Vikstrom S, Wieslander A.
  Title
Lipid dependence and basic kinetics of the purified 1,2-diacylglycerol 3-glucosyltransferase from membranes of Acholeplasma laidlawii.
  Journal
J Biol Chem 272:929-36 (1997)
DOI:10.1074/jbc.272.2.929
Reference
PMID:11294844
  Authors
Berg S, Edman M, Li L, Wikstrom M, Wieslander A.
  Title
Sequence properties of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii membranes. Recognition of a large group of lipid glycosyltransferases in eubacteria and archaea.
  Journal
J Biol Chem 276:22056-63 (2001)
DOI:10.1074/jbc.M102576200
Related
pathway
rno00010  Glycolysis / Gluconeogenesis
rno00071  Fatty acid degradation
rno00564  Glycerophospholipid metabolism
KO pathway
ko00561   
LinkDB

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