KEGG   PATHWAY: sav00230
Entry
sav00230                    Pathway                                
Name
Purine metabolism - Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
Class
Metabolism; Nucleotide metabolism
Pathway map
sav00230  Purine metabolism
sav00230

Module
sav_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:sav00230]
sav_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sav00230]
sav_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sav00230]
sav_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sav00230]
sav_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sav00230]
Other DBs
GO: 0006163 0042278
Organism
Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA) [GN:sav]
Gene
SAV0017  purA; adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
SAV0136  pnp; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SAV0139  drm; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SAV0145  [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SAV0388  xprT; xanthine phosphoribosyltransferase [KO:K03816] [EC:2.4.2.22]
SAV0390  guaB; inositol-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SAV0391  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
SAV0500  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SAV0510  [KO:K00760] [EC:2.4.2.8]
SAV0556  [KO:K15519] [EC:2.7.1.76 2.7.1.74]
SAV0557  [KO:K15518] [EC:2.7.1.113]
SAV0731  nrdE; ribonuceloside diphosphate reductase major subunit [KO:K00525] [EC:1.17.4.1]
SAV0732  nrdF; ribonucleoside-diphosphate reductase minor subunit [KO:K00526] [EC:1.17.4.1]
SAV1006  [KO:K07816] [EC:2.7.6.5]
SAV1064  [KO:K01588] [EC:5.4.99.18]
SAV1065  purK; phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation chain PurK homolog [KO:K01589] [EC:6.3.4.18]
SAV1066  purC; phosphoribosylaminoimidazolesuccinocarboxamide synthetase homolog [KO:K01923] [EC:6.3.2.6]
SAV1067  [KO:K23264]
SAV1068  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265]
SAV1069  purL; phosphoribosylformylglycinamidine synthetase [KO:K23269]
SAV1070  purF; phosphoribosylpyrophosphate amidotransferase [KO:K00764] [EC:2.4.2.14]
SAV1071  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SAV1072  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SAV1073  purH; bifunctional purine biosynthesis protein [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SAV1074  purD; phosphoribosylamine-glycine ligase [KO:K01945] [EC:6.3.4.13]
SAV1152  [KO:K01519] [EC:3.6.1.66]
SAV1170  [KO:K00926] [EC:2.7.2.2]
SAV1187  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SAV1209  gmk; guanylate kinase homolog [KO:K00942] [EC:2.7.4.8]
SAV1288  [KO:K09769] [EC:3.1.4.16]
SAV1337  [KO:K00364] [EC:1.7.1.7]
SAV1469  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SAV1499  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SAV1593  [KO:K28933]
SAV1634  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SAV1635  apt; adenine phosphoribosyl transferase [KO:K00759] [EC:2.4.2.7]
SAV1908  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SAV2138  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SAV2229  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SAV2288  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
SAV2289  ureB; urease beta subunit [KO:K01429] [EC:3.5.1.5]
SAV2290  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
SAV2491  [KO:K01835] [EC:5.4.2.2]
SAV2509  [KO:K07816] [EC:2.7.6.5]
SAV2617  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SAV2632  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sav00030  Pentose phosphate pathway
sav00220  Arginine biosynthesis
sav00250  Alanine, aspartate and glutamate metabolism
sav00260  Glycine, serine and threonine metabolism
sav00340  Histidine metabolism
sav00630  Glyoxylate and dicarboxylate metabolism
sav00730  Thiamine metabolism
sav00740  Riboflavin metabolism
sav00790  Folate biosynthesis
KO pathway
ko00230   

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