KEGG   PATHWAY: sed00230
Entry
sed00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Dublin
Class
Metabolism; Nucleotide metabolism
Pathway map
sed00230  Purine metabolism
sed00230

Module
sed_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sed00230]
sed_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sed00230]
sed_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sed00230]
sed_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sed00230]
sed_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sed00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Dublin [GN:sed]
Gene
SeD_A0092  [KO:K01525] [EC:3.6.1.41]
SeD_A0153  guaC; guanosine monophosphate reductase [KO:K00364] [EC:1.7.1.7]
SeD_A0185  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SeD_A0228  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
SeD_A0347  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SeD_A0429  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
SeD_A0527  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SeD_A0534  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SeD_A0538  gsk; inosine kinase [KO:K00892] [EC:2.7.1.73]
SeD_A0542  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SeD_A0564  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
SeD_A0571  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
SeD_A0574  [KO:K14977] [EC:3.5.3.26]
SeD_A0575  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
SeD_A0576  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
SeD_A0580  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
SeD_A0581  purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit [KO:K01589] [EC:6.3.4.18]
SeD_A0582  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
SeD_A0787  [KO:K02566] [EC:3.1.3.5]
SeD_A0806  pgm; phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
SeD_A1172  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
SeD_A1366  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
SeD_A1541  prs; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SeD_A1879  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SeD_A2134  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SeD_A2295  [KO:K06952] [EC:3.1.3.89]
SeD_A2344  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SeD_A2621  nrdA; ribonucleoside-diphosphate reductase, alpha subunit [KO:K00525] [EC:1.17.4.1]
SeD_A2622  nrdB; ribonucleoside-diphosphate reductase, beta subunit [KO:K00526] [EC:1.17.4.1]
SeD_A2680  [KO:K08722] [EC:3.1.3.89]
SeD_A2713  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SeD_A2787  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
SeD_A2803  [KO:K01951] [EC:6.3.5.2]
SeD_A2853  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SeD_A2868  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SeD_A2869  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SeD_A2871  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SeD_A2875  [KO:K01951] [EC:6.3.5.2]
SeD_A2876  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SeD_A2896  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SeD_A2943  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
SeD_A2990  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SeD_A3113  [KO:K00525] [EC:1.17.4.1]
SeD_A3114  [KO:K00526] [EC:1.17.4.1]
SeD_A3237  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SeD_A3243  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
SeD_A3244  [KO:K00956] [EC:2.7.7.4]
SeD_A3245  cysD; sulfate adenylyltransferase, subunit 2 [KO:K00957] [EC:2.7.7.4]
SeD_A3268  [KO:K04765] [EC:3.6.1.9]
SeD_A3276  [KO:K00951] [EC:2.7.6.5]
SeD_A3291  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
SeD_A3446  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
SeD_A3536  icc; protein icc [KO:K03651] [EC:3.1.4.53]
SeD_A3538  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SeD_A3863  [KO:K08312] [EC:3.6.1.-]
SeD_A3865  [KO:K20881] [EC:3.1.3.-]
SeD_A4127  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SeD_A4129  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SeD_A4302  gppA; guanosine-5'-triphosphate,3'-diphosphate diphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SeD_A4328  cyaA; adenylate cyclase, class I [KO:K05851] [EC:4.6.1.1]
SeD_A4582  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
SeD_A4583  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SeD_A4763  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SeD_A4801  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SeD_A4832  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SeD_A4849  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
SeD_A4984  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SeD_A4985  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SeD_A4996  [KO:K01529]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sed00030  Pentose phosphate pathway
sed00220  Arginine biosynthesis
sed00250  Alanine, aspartate and glutamate metabolism
sed00260  Glycine, serine and threonine metabolism
sed00340  Histidine metabolism
sed00630  Glyoxylate and dicarboxylate metabolism
sed00730  Thiamine metabolism
sed00740  Riboflavin metabolism
sed00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system