KEGG   PATHWAY: sei00230
Entry
sei00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Paratyphi C
Class
Metabolism; Nucleotide metabolism
Pathway map
sei00230  Purine metabolism
sei00230

Module
sei_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sei00230]
sei_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sei00230]
sei_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sei00230]
sei_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sei00230]
sei_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sei00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Paratyphi C [GN:sei]
Gene
SPC_0095  apaH; diadenosinetetraphosphatase [KO:K01525] [EC:3.6.1.41]
SPC_0152  guaC; guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
SPC_0183  hpt; hypoxanthine-guanine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SPC_0224  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
SPC_0328  gpt; xanthine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SPC_0401  yaiE; hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
SPC_0497  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SPC_0502  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SPC_0506  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
SPC_0509  ushA; UDP-sugar hydrolase 5'-nucleotidase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SPC_0530  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
SPC_0537  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
SPC_0540  ylbA; hypothetical protein [KO:K14977] [EC:3.5.3.26]
SPC_0541  allC; N-carbamoyl-L-amino acid amidohydrolase [KO:K02083] [EC:3.5.3.9]
SPC_0542  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
SPC_0546  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
SPC_0547  purK; phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
SPC_0548  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
SPC_0690  nagD; NagD protein [KO:K02566] [EC:3.1.3.5]
SPC_0707  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SPC_1085  purG; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
SPC_1128  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SPC_1144  guaB; inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SPC_1145  guaA; bifunctional GMP synthase/glutamine amidotransferase protein [KO:K01951] [EC:6.3.5.2]
SPC_1154  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SPC_1156  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SPC_1157  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
SPC_1172  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
SPC_1222  yfeJ; glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
SPC_1238  xapA; purine nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
SPC_1344  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SPC_1376  [KO:K08722] [EC:3.1.3.89]
SPC_1434  nrdB; ribonucleotide-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
SPC_1435  nrdA; ribonucleotide-diphosphate reductase alpha subunit [KO:K00525] [EC:1.17.4.1]
SPC_1711  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SPC_1833  purT; 5'-phosphoribosylglycinamide transformylase [KO:K08289] [EC:6.3.1.21]
SPC_1952  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SPC_2268  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SPC_2512  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SPC_2653  [KO:K07127] [EC:3.5.2.17]
SPC_2771  yfiH; hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SPC_2854  nrdF; ribonucleotide-diphosphate reductase beta subunit [KO:K00526] [EC:1.17.4.1]
SPC_2970  surE; acid phosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SPC_2976  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
SPC_2977  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SPC_2978  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SPC_3004  mazG; hypothetical protein [KO:K04765] [EC:3.6.1.9]
SPC_3013  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
SPC_3026  ygdH; hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
SPC_3168  yggV; putative deoxyribonucleotide triphosphate pyrophosphatase [KO:K01519] [EC:3.6.1.66]
SPC_3257  icc; hypothetical protein [KO:K03651] [EC:3.1.4.53]
SPC_3259  yqiE; hypothetical protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SPC_3563  yrfE; putative NUDIX hydrolase [KO:K08312] [EC:3.6.1.-]
SPC_3565  yrfG; putative hydrolase [KO:K20881] [EC:3.1.3.-]
SPC_3822  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
SPC_3824  spoT; (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SPC_4006  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
SPC_4007  purH; bifunctionalphosphoribosylaminoimidazolecarboxam ide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SPC_4027  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (guanosine pentaphosphatase) [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SPC_4049  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
SPC_4513  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SPC_4552  cpdB; 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SPC_4584  nrdD; anaerobic ribonucleoside triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SPC_4598  [KO:K00926] [EC:2.7.2.2]
SPC_4705  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SPC_4706  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SPC_4717  yjjX; hypothetical protein [KO:K01529]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sei00030  Pentose phosphate pathway
sei00220  Arginine biosynthesis
sei00250  Alanine, aspartate and glutamate metabolism
sei00260  Glycine, serine and threonine metabolism
sei00340  Histidine metabolism
sei00630  Glyoxylate and dicarboxylate metabolism
sei00730  Thiamine metabolism
sei00740  Riboflavin metabolism
sei00790  Folate biosynthesis
KO pathway
ko00230   

DBGET integrated database retrieval system