KEGG   PATHWAY: sel00230
Entry
sel00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Gallinarum/pullorum RKS5078
Class
Metabolism; Nucleotide metabolism
Pathway map
sel00230  Purine metabolism
sel00230

Module
sel_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:sel00230]
sel_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sel00230]
sel_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sel00230]
sel_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sel00230]
sel_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sel00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Gallinarum/pullorum RKS5078 [GN:sel]
Gene
SPUL_0093  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
SPUL_0151  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
SPUL_0186  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
SPUL_0227  dgt; Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
SPUL_0308  purG; Phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
SPUL_0352  ndk; Nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
SPUL_0369  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SPUL_0370  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
SPUL_0375  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SPUL_0377  purN; phosphoribosylglycinamidine myltransferase [KO:K11175] [EC:2.1.2.2]
SPUL_0378  purM; Phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
SPUL_0393  purC; Phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
SPUL_0444  yfeJ; putative amidotransferase [KO:K01951] [EC:6.3.5.2]
SPUL_0460  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
SPUL_0523  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SPUL_0556  [KO:K08722] [EC:3.1.3.89]
SPUL_0613  nrdB; ribonucleoside-diphosphate reductase 1 beta chain [KO:K00526] [EC:1.17.4.1]
SPUL_0614  nrdA; ribonucleoside-diphosphate reductase 1 alpha chain [KO:K00525] [EC:1.17.4.1]
SPUL_0889  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SPUL_1036  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
SPUL_1278  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
SPUL_1594  prsA; Ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SPUL_1767  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
SPUL_1960  [KO:K07127] [EC:3.5.2.17]
SPUL_2265  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
SPUL_2284  nagD; NagD protein [KO:K02566] [EC:3.1.3.5]
SPUL_2425  purE; phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
SPUL_2426  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
SPUL_2427  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
SPUL_2428  [KO:K28795]
SPUL_2429  [KO:K28794]
SPUL_2430  fdrA; FdrA protein [KO:K02381] [EC:2.1.3.5]
SPUL_2433  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
SPUL_2434  [KO:K14977] [EC:3.5.3.26]
SPUL_2437  allB; putative allantoinase [KO:K01466] [EC:3.5.2.5]
SPUL_2444  allA; ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
SPUL_2466  ushA; UDP-sugar hydrolase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SPUL_2470  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
SPUL_2474  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SPUL_2480  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SPUL_2580  [KO:K09913] [EC:2.4.2.1 2.4.2.2]
SPUL_2656  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SPUL_2729  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SPUL_2804  nrdE; ribonucleoside-diphosphate reductase 2 alpha chain [KO:K00525] [EC:1.17.4.1]
SPUL_2805  nrdF; ribonucleoside-diphosphate reductase 2 beta chain [KO:K00526] [EC:1.17.4.1]
SPUL_2926  surE; Acid phosphatase surE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SPUL_2932  cysC; Adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
SPUL_2933  cysN; Sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SPUL_2934  cysD; Sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SPUL_2956  [KO:K04765] [EC:3.6.1.9]
SPUL_2964  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
SPUL_2977  [KO:K06966] [EC:3.2.2.10 3.2.2.-]
SPUL_3105  [KO:K01519] [EC:3.6.1.66]
SPUL_3194  [KO:K03651] [EC:3.1.4.53]
SPUL_3196  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
SPUL_3408  purH; phosphoribosylaminoimidazolecarboxamide formyltransferase and IMP cyclohydrolase (bifunctional enzyme) [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SPUL_3409  purD; phosphoribosylglycineamide synthetase [KO:K01945] [EC:6.3.4.13]
SPUL_3490  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
SPUL_3512  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase (guanosine pentaphosphatase) [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SPUL_3821  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SPUL_3823  gmk; 5'guanylate kinase [KO:K00942] [EC:2.7.4.8]
SPUL_4085  yrfG; putative hydrolase [KO:K20881] [EC:3.1.3.-]
SPUL_4087  yrfE; putative NUDIX hydrolase [KO:K08312] [EC:3.6.1.-]
SPUL_4356  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SPUL_4395  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SPUL_4425  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
SPUL_4441  [KO:K00926] [EC:2.7.2.2]
SPUL_4560  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
SPUL_4561  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
SPUL_4572  [KO:K01529]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sel00030  Pentose phosphate pathway
sel00220  Arginine biosynthesis
sel00250  Alanine, aspartate and glutamate metabolism
sel00260  Glycine, serine and threonine metabolism
sel00340  Histidine metabolism
sel00630  Glyoxylate and dicarboxylate metabolism
sel00730  Thiamine metabolism
sel00740  Riboflavin metabolism
sel00790  Folate biosynthesis
KO pathway
ko00230   

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