KEGG   PATHWAY: sfh00230
Entry
sfh00230                    Pathway                                
Name
Purine metabolism - Sinorhizobium fredii HH103
Class
Metabolism; Nucleotide metabolism
Pathway map
sfh00230  Purine metabolism
sfh00230

Module
sfh_M00005  PRPP biosynthesis, ribose-5P => PRPP [PATH:sfh00230]
sfh_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfh00230]
sfh_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfh00230]
sfh_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfh00230]
sfh_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sfh00230]
sfh_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sfh00230]
sfh_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sfh00230]
Other DBs
GO: 0006163 0042278
Organism
Sinorhizobium fredii HH103 [GN:sfh]
Gene
SFHH103_00007  rdgB; K01516 nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
SFHH103_00097  pdeA; Protein icc homolog [KO:K03651] [EC:3.1.4.53]
SFHH103_00101  cyaD1; putative adenylate cyclase transmembrane protein [KO:K01768] [EC:4.6.1.1]
SFHH103_00411  [KO:K01768] [EC:4.6.1.1]
SFHH103_00440  ppx1; ppx1 [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SFHH103_00445  guaB; inositol-5-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
SFHH103_00539  purD; purD [KO:K01945] [EC:6.3.4.13]
SFHH103_00633  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
SFHH103_00634  cysd1; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
SFHH103_00738  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
SFHH103_00757  spoT; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
SFHH103_00785  [KO:K06952] [EC:3.1.3.89]
SFHH103_00806  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
SFHH103_00826  gmk; gmk [KO:K00942] [EC:2.7.4.8]
SFHH103_00842  ndk; ndk [KO:K00940] [EC:2.7.4.6]
SFHH103_00860  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
SFHH103_00861  purM; 5'-phosphoribosyl-5-aminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
SFHH103_00865  ppx3; ppx3 [KO:K01524] [EC:3.6.1.11 3.6.1.40]
SFHH103_00870  cya; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_01096  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
SFHH103_01189  mazG; Protein mazG homolog [KO:K04765] [EC:3.6.1.9]
SFHH103_01244  dgt; K01129 dGTPase [KO:K01129] [EC:3.1.5.1]
SFHH103_01255  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
SFHH103_01372  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
SFHH103_01382  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
SFHH103_01407  [KO:K01756] [EC:4.3.2.2]
SFHH103_01449  nrdJ; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
SFHH103_01511  purC; phosphoribosylaminoimidazole-succinocarboxamidesynthase [KO:K01923] [EC:6.3.2.6]
SFHH103_01512  purS; Phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
SFHH103_01513  purQ; phosphoribosylformylglycinamidine synthase I [KO:K23265]
SFHH103_01516  purL; phosphoribosylformylglycinamidine synthase II [KO:K23269]
SFHH103_01715  [KO:K01768] [EC:4.6.1.1]
SFHH103_01752  cyaD2; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_02161  [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
SFHH103_02164  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
SFHH103_02167  cyaF; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_02198  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
SFHH103_02241  adeC; adeC [KO:K01486] [EC:3.5.4.2]
SFHH103_02255  xdhA; putative xanthine dehydrogenase, FAD binding subunit [KO:K13481] [EC:1.17.1.4]
SFHH103_02256  xdhB; putative xanthine dehydrogenase, molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
SFHH103_02260  guaD; putative guanine deaminase [KO:K01487] [EC:3.5.4.3]
SFHH103_02262  [KO:K07127] [EC:3.5.2.17]
SFHH103_02263  allA; putative ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
SFHH103_02265  [KO:K16842] [EC:3.5.2.5]
SFHH103_02294  [KO:K01768] [EC:4.6.1.1]
SFHH103_02345  [KO:K01768] [EC:4.6.1.1]
SFHH103_02362  ureC; urease alpha subunit [KO:K01428] [EC:3.5.1.5]
SFHH103_02365  ureB; urease, beta subunit [KO:K01429] [EC:3.5.1.5]
SFHH103_02367  ureA; urease gamma subunit [KO:K01430] [EC:3.5.1.5]
SFHH103_02557  cyaa1; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_02624  hpt; hpt [KO:K00760] [EC:2.4.2.8]
SFHH103_02737  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
SFHH103_02812  [KO:K09769] [EC:3.1.4.16]
SFHH103_02824  [KO:K01768] [EC:4.6.1.1]
SFHH103_02841  purE; K01588 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
SFHH103_02842  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
SFHH103_02859  [KO:K11751] [EC:3.1.3.5 3.6.1.45]
SFHH103_02905  [KO:K01835] [EC:5.4.2.2]
SFHH103_02916  cyaG; adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_03229  guaa1; Glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
SFHH103_03394  [KO:K01129] [EC:3.1.5.1]
SFHH103_03475  purH; bifunctional purine biosynthesis protein PurH; includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
SFHH103_03614  [KO:K01768] [EC:4.6.1.1]
SFHH103_03627  deoD; deoD [KO:K03783] [EC:2.4.2.1]
SFHH103_03631  [KO:K01488] [EC:3.5.4.4]
SFHH103_03632  [KO:K01839] [EC:5.4.2.7]
SFHH103_03695  [KO:K01768] [EC:4.6.1.1]
SFHH103_03827  cyaa3; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_03885  guaa3; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
SFHH103_03960  [KO:K01487] [EC:3.5.4.3]
SFHH103_04113  [KO:K01768] [EC:4.6.1.1]
SFHH103_05011  [KO:K01768] [EC:4.6.1.1]
SFHH103_05082  [KO:K01768] [EC:4.6.1.1]
SFHH103_05111  [KO:K01768] [EC:4.6.1.1]
SFHH103_05185  [KO:K14977] [EC:3.5.3.26]
SFHH103_05193  [KO:K01483] [EC:4.3.2.3]
SFHH103_05572  [KO:K01768] [EC:4.6.1.1]
SFHH103_05581  [KO:K01768] [EC:4.6.1.1]
SFHH103_05652  manB; phosphomannomutase/phosphoglucomutase [KO:K15778] [EC:5.4.2.8 5.4.2.2]
SFHH103_05776  [KO:K16841] [EC:5.1.99.3]
SFHH103_05779  guaD; Putative guanine deaminase [KO:K01487] [EC:3.5.4.3]
SFHH103_05783  xdhB; Putative xanthine dehydrogenase molybdopterin binding subunit [KO:K13482] [EC:1.17.1.4]
SFHH103_05784  xdhA; Putative xanthine dehydrogenase small subunit [KO:K13481] [EC:1.17.1.4]
SFHH103_05785  [KO:K07127] [EC:3.5.2.17]
SFHH103_05786  [KO:K16842] [EC:3.5.2.5]
SFHH103_05838  cyaA; Putative adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_05867  [KO:K16841] [EC:5.1.99.3]
SFHH103_05947  [KO:K01768] [EC:4.6.1.1]
SFHH103_05963  nodQ; Putative ATP-sulfurylase large subunit/adenylylsulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
SFHH103_05964  nodP; Putative ATP-sulfurylase small subunit [KO:K00957] [EC:2.7.7.4]
SFHH103_06058  [KO:K01768] [EC:4.6.1.1]
SFHH103_06118  [KO:K01768] [EC:4.6.1.1]
SFHH103_06139  [KO:K01768] [EC:4.6.1.1]
SFHH103_06175  cyaA; putative adenylate cyclase protein [KO:K01768] [EC:4.6.1.1]
SFHH103_06467  cyaA; putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_06530  [KO:K01768] [EC:4.6.1.1]
SFHH103_06629  cya3; adenylate cyclase [KO:K01768] [EC:4.6.1.1]
SFHH103_06667  [KO:K01466] [EC:3.5.2.5]
SFHH103_06695  [KO:K01768] [EC:4.6.1.1]
SFHH103_06704  [KO:K01768] [EC:4.6.1.1]
SFHH103_06724  nrdF; ribonucleoside-diphosphate reductase beta chain [KO:K00526] [EC:1.17.4.1]
SFHH103_06725  nrdE; ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
SFHH103_06791  [KO:K01768] [EC:4.6.1.1]
SFHH103_06808  [KO:K01768] [EC:4.6.1.1]
SFHh103_09010  [KO:K01768] [EC:4.6.1.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sfh00030  Pentose phosphate pathway
sfh00220  Arginine biosynthesis
sfh00250  Alanine, aspartate and glutamate metabolism
sfh00260  Glycine, serine and threonine metabolism
sfh00340  Histidine metabolism
sfh00630  Glyoxylate and dicarboxylate metabolism
sfh00730  Thiamine metabolism
sfh00740  Riboflavin metabolism
sfh00790  Folate biosynthesis
KO pathway
ko00230   

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