KEGG   PATHWAY: sfug00630
Entry
sfug00630                   Pathway                                
Name
Glyoxylate and dicarboxylate metabolism - Streptomyces fungicidicus
Class
Metabolism; Carbohydrate metabolism
Pathway map
sfug00630  Glyoxylate and dicarboxylate metabolism
sfug00630

Module
sfug_M00621  Glycine cleavage system [PATH:sfug00630]
Other DBs
GO: 0046487 0043648
Organism
Streptomyces fungicidicus [GN:sfug]
Gene
CNQ36_31550  acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CNQ36_19175  acs; acetate--CoA ligase [KO:K01895] [EC:6.2.1.1]
CNQ36_26500  AMP-dependent synthetase [KO:K01895] [EC:6.2.1.1]
CNQ36_26685  malate synthase A [KO:K01638] [EC:2.3.3.9]
CNQ36_21735  malate dehydrogenase [KO:K00024] [EC:1.1.1.37]
CNQ36_12410  citrate synthase [KO:K01647] [EC:2.3.3.1]
CNQ36_15200  citrate synthase [KO:K01647] [EC:2.3.3.1]
CNQ36_25395  acnA; aconitate hydratase AcnA [KO:K01681] [EC:4.2.1.3]
CNQ36_30875  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_01150  acetyl-CoA acetyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_14075  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_20225  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_24605  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_29535  acetyl-CoA C-acyltransferase [KO:K00626] [EC:2.3.1.9]
CNQ36_01460  ccrA; crotonyl-CoA carboxylase/reductase [KO:K14446] [EC:1.3.1.85]
CNQ36_24600  mce; methylmalonyl-CoA epimerase [KO:K05606] [EC:5.1.99.1]
CNQ36_27175  protein meaA [KO:K14447] [EC:5.4.99.63]
CNQ36_22195  acetyl-/propionyl-CoA carboxylase subunit alpha [KO:K11263] [EC:6.4.1.2 6.4.1.3 6.3.4.14]
CNQ36_22220  methylmalonyl-CoA carboxyltransferase [KO:K27094] [EC:6.4.1.3 6.4.1.- 2.1.3.15]
CNQ36_22215  hypothetical protein [KO:K27095]
CNQ36_21950  methylmalonyl-CoA mutase [KO:K01848] [EC:5.4.99.2]
CNQ36_13260  FAD-binding oxidoreductase [KO:K00104] [EC:1.1.99.14]
CNQ36_32365  catalase [KO:K03781] [EC:1.11.1.6]
CNQ36_03475  catalase [KO:K03781] [EC:1.11.1.6]
CNQ36_23615  catalase [KO:K03781] [EC:1.11.1.6]
CNQ36_15475  haloacid dehalogenase [KO:K01091] [EC:3.1.3.18]
CNQ36_06735  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CNQ36_09810  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CNQ36_09845  glutamine synthetase [KO:K01915] [EC:6.3.1.2]
CNQ36_09975  glnA; type I glutamate--ammonia ligase [KO:K01915] [EC:6.3.1.2]
CNQ36_21790  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CNQ36_24430  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CNQ36_25030  serine hydroxymethyltransferase [KO:K00600] [EC:2.1.2.1]
CNQ36_05435  glycine dehydrogenase (aminomethyl-transferring) [KO:K00281] [EC:1.4.4.2]
CNQ36_25040  gcvT; glycine cleavage system protein T [KO:K00605] [EC:2.1.2.10]
CNQ36_09725  lpdA; dihydrolipoyl dehydrogenase [KO:K00382] [EC:1.8.1.4]
CNQ36_25035  gcvH; glycine cleavage system protein H [KO:K02437]
CNQ36_26510  gcl; glyoxylate carboligase [KO:K01608] [EC:4.1.1.47]
CNQ36_26530  hydroxypyruvate isomerase [KO:K01816] [EC:5.3.1.22]
CNQ36_26525  2-hydroxy-3-oxopropionate reductase [KO:K00042] [EC:1.1.1.60]
CNQ36_27140  glycerate kinase [KO:K00865] [EC:2.7.1.165]
CNQ36_10510  keto-deoxy-phosphogluconate aldolase [KO:K01625] [EC:4.1.2.14 4.1.3.42]
CNQ36_23935  multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit [KO:K01616] [EC:2.2.1.5 4.1.1.71 1.2.4.2 2.3.1.61]
CNQ36_07100  formate dehydrogenase [KO:K00127]
CNQ36_15130  purU; formyltetrahydrofolate deformylase [KO:K01433] [EC:3.5.1.10]
Compound
C00007  Oxygen
C00011  CO2
C00014  Ammonia
C00022  Pyruvate
C00024  Acetyl-CoA
C00025  L-Glutamate
C00026  2-Oxoglutarate
C00027  Hydrogen peroxide
C00033  Acetate
C00036  Oxaloacetate
C00037  Glycine
C00042  Succinate
C00048  Glyoxylate
C00058  Formate
C00064  L-Glutamine
C00065  L-Serine
C00091  Succinyl-CoA
C00100  Propanoyl-CoA
C00111  Glycerone phosphate
C00136  Butanoyl-CoA
C00149  (S)-Malate
C00158  Citrate
C00160  Glycolate
C00168  Hydroxypyruvate
C00197  3-Phospho-D-glycerate
C00209  Oxalate
C00258  D-Glycerate
C00266  Glycolaldehyde
C00311  Isocitrate
C00313  Oxalyl-CoA
C00332  Acetoacetyl-CoA
C00417  cis-Aconitate
C00552  meso-Tartaric acid
C00631  2-Phospho-D-glycerate
C00683  (S)-Methylmalonyl-CoA
C00798  Formyl-CoA
C00877  Crotonoyl-CoA
C00888  Pentanoyl-CoA
C00898  (R,R)-Tartaric acid
C00975  Dihydroxyfumarate
C00988  2-Phosphoglycolate
C01127  4-Hydroxy-2-oxoglutarate
C01146  2-Hydroxy-3-oxopropanoate
C01182  D-Ribulose 1,5-bisphosphate
C01213  (R)-Methylmalonyl-CoA
C01380  Ethylene glycol
C01732  Mesaconate
C01989  3-Ethylmalate
C01990  3-Oxalomalate
C02123  3-Propylmalate
C02405  Formyl phosphate
C03217  2-Hydroxy-3-oxoadipate
C03459  2-Hydroxy-3-oxosuccinate
C03548  trans-2,3-Epoxysuccinate
C03561  (R)-3-Hydroxybutanoyl-CoA
C03618  L-threo-3-Methylaspartate
C04348  L-Malyl-CoA
C06027  L-erythro-3-Methylmalyl-CoA
C06028  2-Methylfumaryl-CoA
C06049  N-Formylderivatives
C18026  (2S)-Ethylmalonyl-CoA
C18324  (2S)-Methylsuccinyl-CoA
C20238  (2R)-Ethylmalonyl-CoA
C22337  D-Ribulose 1-phosphate
Reference
  Authors
Njau RK, Herndon CA, Hawes JW.
  Title
Novel beta-hydroxyacid dehydrogenases in Escherichia coli and Haemophilus influenzae.
  Journal
J Biol Chem 275:38780-6 (2000)
DOI:10.1074/jbc.M007432200
Reference
  Authors
Zarzycki J, Schlichting A, Strychalsky N, Muller M, Alber BE, Fuchs G
  Title
Mesaconyl-coenzyme A hydratase, a new enzyme of two central carbon metabolic pathways in bacteria.
  Journal
J Bacteriol 190:1366-74 (2008)
DOI:10.1128/JB.01621-07
Reference
  Authors
Erb TJ, Retey J, Fuchs G, Alber BE
  Title
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases.
  Journal
J Biol Chem 283:32283-93 (2008)
DOI:10.1074/jbc.M805527200
Reference
PMID:9596633
  Authors
Coschigano KT, Melo-Oliveira R, Lim J, Coruzzi GM
  Title
Arabidopsis gls mutants and distinct Fd-GOGAT genes. Implications for photorespiration and primary nitrogen assimilation.
  Journal
Plant Cell 10:741-52 (1998)
DOI:10.1105/tpc.10.5.741
Reference
  Authors
Masclaux-Daubresse C, Reisdorf-Cren M, Pageau K, Lelandais M, Grandjean O, Kronenberger J, Valadier MH, Feraud M, Jouglet T, Suzuki A
  Title
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco.
  Journal
Plant Physiol 140:444-56 (2006)
DOI:10.1104/pp.105.071910
Reference
  Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
  Title
A methylaspartate cycle in haloarchaea.
  Journal
Science 331:334-7 (2011)
DOI:10.1126/science.1196544
Reference
  Authors
Serrano JA, Bonete MJ
  Title
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
  Journal
Biochim Biophys Acta 1520:154-62 (2001)
DOI:10.1016/S0167-4781(01)00263-9
Related
pathway
sfug00010  Glycolysis / Gluconeogenesis
sfug00020  Citrate cycle (TCA cycle)
sfug00030  Pentose phosphate pathway
sfug00053  Ascorbate and aldarate metabolism
sfug00071  Fatty acid degradation
sfug00230  Purine metabolism
sfug00250  Alanine, aspartate and glutamate metabolism
sfug00260  Glycine, serine and threonine metabolism
sfug00620  Pyruvate metabolism
sfug00710  Carbon fixation by Calvin cycle
sfug00750  Vitamin B6 metabolism
sfug00910  Nitrogen metabolism
KO pathway
ko00630   
LinkDB

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