KEGG   PATHWAY: sfug00230
Entry
sfug00230                   Pathway                                
Name
Purine metabolism - Streptomyces fungicidicus
Class
Metabolism; Nucleotide metabolism
Pathway map
sfug00230  Purine metabolism
sfug00230

Module
sfug_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sfug00230]
sfug_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sfug00230]
sfug_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sfug00230]
sfug_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sfug00230]
sfug_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sfug00230]
sfug_M00546  Purine degradation, xanthine => urea [PATH:sfug00230]
sfug_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sfug00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces fungicidicus [GN:sfug]
Gene
CNQ36_32660  phosphoglucomutase, alpha-D-glucose phosphate-specific [KO:K01835] [EC:5.4.2.2]
CNQ36_14275  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
CNQ36_16505  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
CNQ36_16590  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
CNQ36_21700  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
CNQ36_16520  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
CNQ36_16530  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
CNQ36_16525  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
CNQ36_16500  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
CNQ36_13980  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
CNQ36_13975  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
CNQ36_16575  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
CNQ36_05030  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
CNQ36_21705  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
CNQ36_06085  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
CNQ36_16155  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
CNQ36_12920  TIGR01457 family HAD-type hydrolase [KO:K02566] [EC:3.1.3.5]
CNQ36_22175  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
CNQ36_09250  laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
CNQ36_19420  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
CNQ36_21495  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
CNQ36_21500  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
CNQ36_11885  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
CNQ36_13150  rdgB; non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
CNQ36_32950  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
CNQ36_03055  oxidoreductase [KO:K11177] [EC:1.17.1.4]
CNQ36_32945  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
CNQ36_03060  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
CNQ36_32940  oxidoreductase [KO:K13483]
CNQ36_03065  (2Fe-2S)-binding protein [KO:K13483]
CNQ36_21570  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
CNQ36_05850  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
CNQ36_05910  guanylate kinase [KO:K00942] [EC:2.7.4.8]
CNQ36_23720  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
CNQ36_28970  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
CNQ36_23715  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
CNQ36_11240  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
CNQ36_06075  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CNQ36_28925  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
CNQ36_02670  hypothetical protein [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CNQ36_14130  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CNQ36_19660  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
CNQ36_22230  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
CNQ36_18715  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
CNQ36_09615  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
CNQ36_31915  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CNQ36_20885  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CNQ36_22100  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
CNQ36_11545  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
CNQ36_08910  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
CNQ36_21180  adenylate kinase [KO:K00939] [EC:2.7.4.3]
CNQ36_25990  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
CNQ36_06165  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
CNQ36_16675  HIT family protein [KO:K19710] [EC:2.7.7.53]
CNQ36_26105  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
CNQ36_26095  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CNQ36_29745  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
CNQ36_26100  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CNQ36_29740  sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
CNQ36_26555  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
CNQ36_26550  uraH; 5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
CNQ36_21890  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
CNQ36_26545  uraD; OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
CNQ36_26705  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
CNQ36_26710  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
CNQ36_04805  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
CNQ36_04810  urease subunit beta [KO:K01429] [EC:3.5.1.5]
CNQ36_04815  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sfug00030  Pentose phosphate pathway
sfug00220  Arginine biosynthesis
sfug00250  Alanine, aspartate and glutamate metabolism
sfug00260  Glycine, serine and threonine metabolism
sfug00340  Histidine metabolism
sfug00630  Glyoxylate and dicarboxylate metabolism
sfug00730  Thiamine metabolism
sfug00740  Riboflavin metabolism
sfug00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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