KEGG   PATHWAY: sglc00230
Entry
sglc00230                   Pathway                                
Name
Purine metabolism - Sphingomonas glaciei
Class
Metabolism; Nucleotide metabolism
Pathway map
sglc00230  Purine metabolism
sglc00230

Module
sglc_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sglc00230]
sglc_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sglc00230]
sglc_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sglc00230]
sglc_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sglc00230]
sglc_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sglc00230]
Other DBs
GO: 0006163 0042278
Organism
Sphingomonas glaciei [GN:sglc]
Gene
M1K48_10255  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
M1K48_04120  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
M1K48_10945  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
M1K48_09150  purT; formate-dependent phosphoribosylglycinamide formyltransferase [KO:K08289] [EC:6.3.1.21]
M1K48_12520  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
M1K48_13895  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
M1K48_13890  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
M1K48_04855  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
M1K48_09260  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
M1K48_09255  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
M1K48_04325  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
M1K48_03815  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
M1K48_09925  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
M1K48_06475  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
M1K48_04415  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
M1K48_01925  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
M1K48_11110  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
M1K48_04920  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
M1K48_04875  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
M1K48_05895  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
M1K48_07535  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
M1K48_12250  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
M1K48_11195  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
M1K48_11170  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
M1K48_12645  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
M1K48_10630  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
M1K48_07380  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
M1K48_12375  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
M1K48_04705  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
M1K48_13595  adenylate kinase [KO:K00939] [EC:2.7.4.3]
M1K48_03275  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
M1K48_10455  cysC; adenylyl-sulfate kinase [KO:K00955] [EC:2.7.7.4 2.7.1.25]
M1K48_10450  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sglc00030  Pentose phosphate pathway
sglc00220  Arginine biosynthesis
sglc00250  Alanine, aspartate and glutamate metabolism
sglc00260  Glycine, serine and threonine metabolism
sglc00340  Histidine metabolism
sglc00630  Glyoxylate and dicarboxylate metabolism
sglc00730  Thiamine metabolism
sglc00740  Riboflavin metabolism
sglc00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

DBGET integrated database retrieval system