KEGG   PATHWAY: sit00230
Entry
sit00230                    Pathway                                
Name
Purine metabolism - Ruegeria sp. TM1040
Class
Metabolism; Nucleotide metabolism
Pathway map
sit00230  Purine metabolism
sit00230

Module
sit_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sit00230]
sit_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sit00230]
sit_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sit00230]
sit_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sit00230]
sit_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sit00230]
sit_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:sit00230]
sit_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:sit00230]
Other DBs
GO: 0006163 0042278
Organism
Ruegeria sp. TM1040 [GN:sit]
Gene
TM1040_1570  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
TM1040_0652  phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I [KO:K15778] [EC:5.4.2.8 5.4.2.2]
TM1040_2075  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
TM1040_1787  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
TM1040_1946  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
TM1040_1475  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
TM1040_1118  phosphoribosylformylglycinamidine synthase subunit II [KO:K23269] [EC:6.3.5.3]
TM1040_1464  phosphoribosylformylglycinamidine synthetase PurS [KO:K23264] [EC:6.3.5.3]
TM1040_1463  phosphoribosylformylglycinamidine synthase subunit I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
TM1040_1476  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
TM1040_0603  phosphoribosylaminoimidazole carboxylase [KO:K01589] [EC:6.3.4.18]
TM1040_0604  phosphoribosylaminoimidazole carboxylase catalytic subunit [KO:K01588] [EC:5.4.99.18]
TM1040_1465  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
TM1040_1011  Adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
TM1040_0091  IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
TM1040_2325  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
TM1040_1548  5'-Nucleotidase-like protein [KO:K11751] [EC:3.1.3.5 3.6.1.45]
TM1040_1791  5'-nucleotidase / 3'-nucleotidase / exopolyphosphatase [KO:K03787] [EC:3.1.3.5 3.1.3.6]
TM1040_3108  purine-nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
TM1040_0618  protein of unknown function DUF152 [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
TM1040_1368  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
TM1040_1224  inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
TM1040_0957  nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
TM1040_2871  Ham1-like protein [KO:K01519] [EC:3.6.1.66]
TM1040_1146  Xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
TM1040_0499  molybdopterin dehydrogenase FAD-binding [KO:K13481] [EC:1.17.1.4]
TM1040_2704  molybdopterin dehydrogenase FAD-binding [KO:K13481] [EC:1.17.1.4]
TM1040_2705  Xanthine oxidase / xanthine dehydrogenase, molybdenum binding subunit apoprotein [KO:K13482] [EC:1.17.1.4]
TM1040_0498  xanthine dehydrogenase, molybdenum binding subunit apoprotein / Xanthine oxidase [KO:K13482] [EC:1.17.1.4]
TM1040_1375  GMP synthase (glutamine-hydrolyzing) [KO:K01951] [EC:6.3.5.2]
TM1040_3054  glutamine amidotransferase [KO:K01951] [EC:6.3.5.2]
TM1040_1905  guanine deaminase [KO:K01487] [EC:3.5.4.3]
TM1040_3479  guanine deaminase [KO:K01487] [EC:3.5.4.3]
TM1040_1266  guanylate kinase [KO:K00942] [EC:2.7.4.8]
TM1040_1151  ribonucleoside-diphosphate reductase class II [KO:K00525] [EC:1.17.4.1]
TM1040_0519  ribonucleoside-diphosphate reductase class Ib alpha subunit [KO:K00525] [EC:1.17.4.1]
TM1040_0518  ribonucleoside-diphosphate reductase class Ib beta subunit [KO:K00526] [EC:1.17.4.1]
TM1040_0902  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
TM1040_0145  Deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
TM1040_2836  metal dependent phosphohydrolase [KO:K06952] [EC:3.1.3.89]
TM1040_2565  relA; metal dependent phosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
TM1040_1857  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
TM1040_1183  Ppx/GppA phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
TM1040_2619  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_0613  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_2648  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_0104  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_2654  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_2124  adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_1952  Tetratricopeptide TPR_2 [KO:K01768] [EC:4.6.1.1]
TM1040_2512  putative adenylate/guanylate cyclase [KO:K01768] [EC:4.6.1.1]
TM1040_1969  purA; Adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
TM1040_2800  AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
TM1040_2799  Adenine deaminase [KO:K01486] [EC:3.5.4.2]
TM1040_1036  Twin-arginine translocation pathway signal [KO:K01119] [EC:3.1.4.16 3.1.3.6]
TM1040_0169  5'-Nucleotidase-like protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
TM1040_1901  hypothetical protein [KO:K09769] [EC:3.1.4.16]
TM1040_0276  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
TM1040_1490  Adenylate kinase [KO:K00939] [EC:2.7.4.3]
TM1040_0936  MazG family protein [KO:K04765] [EC:3.6.1.9]
TM1040_3316  metallophosphoesterase [KO:K03651] [EC:3.1.4.53]
TM1040_0612  adenylylsulfate kinase / sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
TM1040_3476  Transthyretin [KO:K07127] [EC:3.5.2.17]
TM1040_3475  polysaccharide deacetylase [KO:K16842] [EC:3.5.2.5]
TM1040_2689  Amidase hydantoinase/carbamoylase [KO:K02083] [EC:3.5.3.9]
TM1040_3472  protein of unknown function DUF861 cupin_3 [KO:K14977] [EC:3.5.3.26]
TM1040_3474  Ureidoglycolate hydrolase [KO:K01483] [EC:4.3.2.3]
TM1040_0385  urease. Metallo peptidase. MEROPS family M38 [KO:K01428] [EC:3.5.1.5]
TM1040_0386  urease beta subunit [KO:K01429] [EC:3.5.1.5]
TM1040_0387  urease gamma subunit [KO:K01430] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sit00030  Pentose phosphate pathway
sit00220  Arginine biosynthesis
sit00250  Alanine, aspartate and glutamate metabolism
sit00260  Glycine, serine and threonine metabolism
sit00340  Histidine metabolism
sit00630  Glyoxylate and dicarboxylate metabolism
sit00730  Thiamine metabolism
sit00740  Riboflavin metabolism
sit00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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