KEGG   PATHWAY: spo00100
Entry
spo00100                    Pathway                                
Name
Steroid biosynthesis - Schizosaccharomyces pombe (fission yeast)
Class
Metabolism; Lipid metabolism
Pathway map
spo00100  Steroid biosynthesis
spo00100

Module
spo_M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol [PATH:spo00100]
Other DBs
GO: 0016126
Organism
Schizosaccharomyces pombe (fission yeast) [GN:spo]
Gene
2541110  erg9; squalene synthase Erg9 [KO:K00801] [EC:2.5.1.21]
2541106  erg1; squalene monooxygenase Erg1 [KO:K00511] [EC:1.14.14.17]
2542882  erg7; lanosterol synthase Erg7 [KO:K01852] [EC:5.4.99.7]
2542599  erg11; sterol 14-demethylase [KO:K05917] [EC:1.14.14.154 1.14.15.36]
2540113  erg24; C-14 sterol reductase Erg24 [KO:K00222] [EC:1.3.1.70]
2543373  erg25; C-4 methylsterol oxidase [KO:K07750] [EC:1.14.18.9]
2540634  erg26; 3 beta-hydroxysteroid dehydrogenase/delta 5-to-4-isomerase [KO:K07748] [EC:1.1.1.170]
2540195  erg27; 3-keto sterol reductase [KO:K09827] [EC:1.1.1.270]
3361266  erg32; C-5 sterol desaturase Erg32 [KO:K00227] [EC:1.14.19.20]
2542109  erg31; C-5 sterol desaturase Erg31 [KO:K00227] [EC:1.14.19.20]
2539344  SPOM_SPCC1672.09; triglyceride lipase-cholesterol esterase [KO:K01052] [EC:3.1.1.13]
2542205  ptl3; triacylglycerol lipase [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
2542851  are1; acyl-coA-sterol acyltransferase Are1 [KO:K00637] [EC:2.3.1.26]
2538854  are2; acyl-coA-sterol acyltransferase Are2 [KO:K00637] [EC:2.3.1.26]
2539602  erg6; sterol 24-C-methyltransferase Erg6 [KO:K00559] [EC:2.1.1.41]
2541992  erg2; C-8 sterol isomerase Erg2 [KO:K09829] [EC:5.-.-.-]
2542469  erg5; C-22 sterol desaturase Erg5 [KO:K09831] [EC:1.14.19.41]
2541740  erg4; C-24(28) sterol reductase Erg4 [KO:K00223] [EC:1.3.1.71]
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00751  Squalene
C01054  (S)-2,3-Epoxysqualene
C01164  7-Dehydrocholesterol
C01189  Lathosterol
C01561  Calcidiol
C01673  Calcitriol
C01694  Ergosterol
C01724  Lanosterol
C01753  beta-Sitosterol
C01789  Campesterol
C01802  Desmosterol
C01902  Cycloartenol
C01943  Obtusifoliol
C02141  Cycloeucalenol
C02530  Cholesterol ester
C03428  Presqualene diphosphate
C03845  5alpha-Cholest-8-en-3beta-ol
C04525  Fecosterol
C05103  4alpha-Methylzymosterol
C05107  7-Dehydrodesmosterol
C05108  14-Demethyllanosterol
C05109  24,25-Dihydrolanosterol
C05437  Zymosterol
C05439  5alpha-Cholesta-7,24-dien-3beta-ol
C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
C05441  Vitamin D2
C05442  Stigmasterol
C05443  Vitamin D3
C07712  Secalciferol
C08813  Brassicasterol
C08821  Isofucosterol
C08830  24-Methylidenecycloartanol
C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
C11522  24-Methylenelophenol
C11523  24-Ethylidenelophenol
C15776  4alpha-Methylfecosterol
C15777  Episterol
C15780  5-Dehydroepisterol
C15781  24-Methylenecholesterol
C15782  Delta7-Avenasterol
C15783  5-Dehydroavenasterol
C15808  4alpha-Methylzymosterol-4-carboxylate
C15816  3-Keto-4-methylzymosterol
C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
C18231  Calcitetrol
C21106  24-epi-Campesterol
C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
C22116  3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate
C22119  3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate
C22120  4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
C22121  Cycloeucalenone
C22122  Episterone
C22123  Avenastenone
C22136  Zymosterone
Reference
  Authors
Koshiba K, Kamiya Y.
  Title
[Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  Journal
Koudansya saientific:199-138 (2002)
Reference
PMID:16531502
  Authors
Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  Title
Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  Journal
Plant Cell 18:1008-22 (2006)
DOI:10.1105/tpc.105.036012
Reference
PMID:12777052
  Authors
Lange BM, Ghassemian M.
  Title
Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  Journal
Plant Mol Biol 51:925-48 (2003)
DOI:10.1023/A:1023005504702
Related
pathway
spo00900  Terpenoid backbone biosynthesis
KO pathway
ko00100   
LinkDB

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