KEGG   PATHWAY: stro00230
Entry
stro00230                   Pathway                                
Name
Purine metabolism - Streptomyces sp. MOE7
Class
Metabolism; Nucleotide metabolism
Pathway map
stro00230  Purine metabolism
stro00230

Module
stro_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:stro00230]
stro_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:stro00230]
stro_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:stro00230]
stro_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:stro00230]
stro_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:stro00230]
stro_M00546  Purine degradation, xanthine => urea [PATH:stro00230]
stro_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:stro00230]
stro_M00959  Guanine ribonucleotide degradation, GMP => Urate [PATH:stro00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces sp. MOE7 [GN:stro]
Gene
STRMOE7_16225  ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
STRMOE7_18615  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
STRMOE7_18695  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
STRMOE7_23760  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
STRMOE7_18625  phosphoribosylformylglycinamidine synthase II [KO:K23269] [EC:6.3.5.3]
STRMOE7_18635  phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
STRMOE7_18630  phosphoribosylformylglycinamidine synthase I [KO:K23265] [EC:6.3.5.3 3.5.1.2]
STRMOE7_18610  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
STRMOE7_15825  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
STRMOE7_15820  5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
STRMOE7_18680  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
STRMOE7_34830  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
STRMOE7_23765  bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
STRMOE7_08120  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
STRMOE7_08410  bifunctional metallophosphatase/5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
STRMOE7_28760  phosphatase [KO:K11751] [EC:3.1.3.5 3.6.1.45]
STRMOE7_14795  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
STRMOE7_24370  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
STRMOE7_11200  laccase [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
STRMOE7_33715  rihB; ribonucleoside hydrolase [KO:K25589] [EC:3.2.2.2 3.2.2.3]
STRMOE7_21950  hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
STRMOE7_17315  guanosine monophosphate reductase [KO:K00088] [EC:1.1.1.205]
STRMOE7_17320  IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
STRMOE7_13850  nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
STRMOE7_15065  non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [KO:K01519] [EC:3.6.1.66]
STRMOE7_30015  xanthine dehydrogenase [KO:K11177] [EC:1.17.1.4]
STRMOE7_33230  oxidoreductase [KO:K11177] [EC:1.17.1.4]
STRMOE7_30010  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
STRMOE7_33225  molybdopterin dehydrogenase [KO:K11178] [EC:1.17.1.4]
STRMOE7_30005  (2Fe-2S)-binding protein [KO:K13483]
STRMOE7_33220  (2Fe-2S)-binding protein [KO:K13483]
STRMOE7_23590  glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
STRMOE7_07860  inosine 5-monophosphate dehydrogenase [KO:K26110] [EC:1.7.1.7]
STRMOE7_07055  tRNA-specific adenosine deaminase [KO:K01487] [EC:3.5.4.3]
STRMOE7_07945  guanylate kinase [KO:K00942] [EC:2.7.4.8]
STRMOE7_28265  ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent [KO:K00525] [EC:1.17.4.1]
STRMOE7_25705  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
STRMOE7_25700  ribonucleoside-diphosphate reductase [KO:K00526] [EC:1.17.4.1]
STRMOE7_26760  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
STRMOE7_13070  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
STRMOE7_08115  GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
STRMOE7_28210  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
STRMOE7_22215  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STRMOE7_16080  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STRMOE7_24465  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
STRMOE7_06315  adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
STRMOE7_18730  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
STRMOE7_11570  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
STRMOE7_24290  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
STRMOE7_17750  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
STRMOE7_13080  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
STRMOE7_10815  bifunctional metallophosphatase/5'-nucleotidase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
STRMOE7_17535  adenylate kinase [KO:K00939] [EC:2.7.4.3]
STRMOE7_08210  HIT family hydrolase [KO:K19710] [EC:2.7.7.53]
STRMOE7_29820  adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
STRMOE7_29810  sulfate adenylyltransferase [KO:K00956] [EC:2.7.7.4]
STRMOE7_29815  sulfate adenylyltransferase small subunit [KO:K00957] [EC:2.7.7.4]
STRMOE7_30430  urate oxidase [KO:K00365] [EC:1.7.3.3]
STRMOE7_30425  5-hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
STRMOE7_24110  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
STRMOE7_30420  OHCU decarboxylase [KO:K16840] [EC:4.1.1.97]
STRMOE7_30500  Asp/Glu/hydantoin racemase [KO:K16841] [EC:5.1.99.3]
STRMOE7_30510  allantoinase [KO:K01466] [EC:3.5.2.5]
STRMOE7_14010  allantoicase [KO:K01477] [EC:3.5.3.4]
STRMOE7_30515  allantoicase [KO:K01477] [EC:3.5.3.4]
STRMOE7_27135  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
STRMOE7_34940  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
STRMOE7_34935  urease subunit beta [KO:K01429] [EC:3.5.1.5]
STRMOE7_34930  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
STRMOE7_27130  urease subunit gamma [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
stro00030  Pentose phosphate pathway
stro00220  Arginine biosynthesis
stro00250  Alanine, aspartate and glutamate metabolism
stro00260  Glycine, serine and threonine metabolism
stro00340  Histidine metabolism
stro00630  Glyoxylate and dicarboxylate metabolism
stro00730  Thiamine metabolism
stro00740  Riboflavin metabolism
stro00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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