KEGG   PATHWAY: sty00230
Entry
sty00230                    Pathway                                
Name
Purine metabolism - Salmonella enterica subsp. enterica serovar Typhi CT18
Class
Metabolism; Nucleotide metabolism
Pathway map
sty00230  Purine metabolism
sty00230

Module
sty_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:sty00230]
sty_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:sty00230]
sty_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:sty00230]
sty_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:sty00230]
sty_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:sty00230]
Other DBs
GO: 0006163 0042278
Organism
Salmonella enterica subsp. enterica serovar Typhi CT18 [GN:sty]
Gene
HCM2.0121c  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HCM2.0122c  [KO:K00525] [EC:1.17.4.1]
STY0103  apaH; bis(5'-nucleosyl)-tetraphosphatase [KO:K01525] [EC:3.6.1.41]
STY0163  guaC; GMP reductase [KO:K00364] [EC:1.7.1.7]
STY0192  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
STY0230  dgt; deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
STY0362  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
STY0424  yaiE; hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
STY0527  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
STY0532  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
STY0535  gsk; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
STY0571  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
STY0574  [KO:K14977] [EC:3.5.3.26]
STY0575  allC; allantoate amidohydrolase [KO:K02083] [EC:3.5.3.9]
STY0576  allD; ureidoglycolate dehydrogenase [KO:K00073] [EC:1.1.1.350]
STY0580  arcC; carbamate kinase [KO:K00926] [EC:2.7.2.2]
STY0581  purK; 5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
STY0582  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
STY0719  nagD; phosphatase NagD [KO:K02566] [EC:3.1.3.5]
STY0736  pgm; phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
STY1129  [KO:K07127] [EC:3.5.2.17]
STY1272  purB; adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
STY1658  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
STY1906  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
STY2089  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
STY2211  amn; AMP nucleosidase [KO:K01241] [EC:3.2.2.4]
STY2506  nrdA; ribonucleoside-diphosphate reductase 1 subunit alpha [KO:K00525] [EC:1.17.4.1]
STY2507  nrdB; ribonucleoside-diphosphate reductase 1 subunit beta [KO:K00526] [EC:1.17.4.1]
STY2562  [KO:K08722] [EC:3.1.3.89]
STY2592  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
STY2658  xapA; xanthosine phosphorylase [KO:K03783] [EC:2.4.2.1]
STY2675  [KO:K01951] [EC:6.3.5.2]
STY2725  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
STY2740  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
STY2741  purN; phosphoribosylglycinamidine myltransferase [KO:K11175] [EC:2.1.2.2]
STY2743  ppx; exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STY2751  guaA; GMP synthase [KO:K01951] [EC:6.3.5.2]
STY2752  guaB; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
STY2771  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
STY2812  purL; phosphoribosylformylglycineamide synthetase [KO:K01952] [EC:6.3.5.3]
STY2850  yfiH; hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
STY2932  nrdE; ribonucleoside-diphosphate reductase 2 subunit alpha [KO:K00525] [EC:1.17.4.1]
STY2933  nrdF; ribonucleoside-diphosphate reductase 2 subunit beta [KO:K00526] [EC:1.17.4.1]
STY3052  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
STY3058  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
STY3059  cysN; ATP sulfurylase [KO:K00956] [EC:2.7.7.4]
STY3060  cysD; ATP sulfurylase [KO:K00957] [EC:2.7.7.4]
STY3083  [KO:K04765] [EC:3.6.1.9]
STY3094  relA; GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
STY3108  ygdH; hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
STY3256  [KO:K01519] [EC:3.6.1.66]
STY3361  icc; 3',5' cAMP phosphodiesterase [KO:K03651] [EC:3.1.4.53]
STY3363  [KO:K01515] [EC:3.6.1.13 3.6.1.-]
STY3620  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
STY3641  gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
STY3709  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
STY3710  purD; phosphoribosylglycineamide synthetase [KO:K01945] [EC:6.3.4.13]
STY4050  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
STY4052  gmk; 5'guanylate kinase [KO:K00942] [EC:2.7.4.8]
STY4300  yrfG; hydrolase [KO:K20881] [EC:3.1.3.-]
STY4302  yrfE; ADP compounds hydrolase NudE [KO:K08312] [EC:3.6.1.-]
STY4723  purA; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
STY4761  cpdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
STY4791  nrdD; anaerobic ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
STY4804  [KO:K00926] [EC:2.7.2.2]
STY4920  deoB; phosphopentomutase [KO:K01839] [EC:5.4.2.7]
STY4921  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
sty00030  Pentose phosphate pathway
sty00220  Arginine biosynthesis
sty00250  Alanine, aspartate and glutamate metabolism
sty00260  Glycine, serine and threonine metabolism
sty00340  Histidine metabolism
sty00630  Glyoxylate and dicarboxylate metabolism
sty00730  Thiamine metabolism
sty00740  Riboflavin metabolism
sty00790  Folate biosynthesis
KO pathway
ko00230   

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