KEGG   PATHWAY: sund00330
Entry
sund00330                   Pathway                                
Name
Arginine and proline metabolism - Sceloporus undulatus (fence lizard)
Class
Metabolism; Amino acid metabolism
Pathway map
sund00330  Arginine and proline metabolism
sund00330

Module
sund_M00015  Proline biosynthesis, glutamate => proline [PATH:sund00330]
sund_M00047  Creatine pathway [PATH:sund00330]
sund_M00134  Polyamine biosynthesis, arginine => ornithine => putrescine [PATH:sund00330]
sund_M00135  GABA biosynthesis, eukaryotes, putrescine => GABA [PATH:sund00330]
sund_M00970  Proline degradation, proline => glutamate [PATH:sund00330]
sund_M00972  Proline metabolism [PATH:sund00330]
Other DBs
GO: 0006525 0006560
Organism
Sceloporus undulatus (fence lizard) [GN:sund]
Gene
121914942  GOT2; LOW QUALITY PROTEIN: aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
121915035  ARG2; arginase-2, mitochondrial [KO:K01476] [EC:3.5.3.1]
121915769  ODC1; ornithine decarboxylase [KO:K01581] [EC:4.1.1.17]
121916133  CKM; creatine kinase M-type [KO:K27382]
121916265  AZIN2; antizyme inhibitor 2 [KO:K01583] [EC:4.1.1.19]
121916508  [KO:K00318] [EC:1.5.5.2]
121916538  NOS1; nitric oxide synthase, brain isoform X1 [KO:K13240] [EC:1.14.13.39]
121916562  ALDH2; aldehyde dehydrogenase, mitochondrial [KO:K00128] [EC:1.2.1.3]
121916653  DAO; D-amino-acid oxidase [KO:K00273] [EC:1.4.3.3]
121916849  ALDH3A2; aldehyde dehydrogenase family 3 member A2 isoform X1 [KO:K00128] [EC:1.2.1.3]
121917020  [KO:K13241] [EC:1.14.13.39]
121919270  CARNS1; LOW QUALITY PROTEIN: carnosine synthase 1 [KO:K14755] [EC:6.3.2.11]
121919790  AMD1; S-adenosylmethionine decarboxylase proenzyme isoform X1 [KO:K01611] [EC:4.1.1.50]
121920642  ALDH7A1; LOW QUALITY PROTEIN: alpha-aminoadipic semialdehyde dehydrogenase [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
121921614  P4HA2; prolyl 4-hydroxylase subunit alpha-2 isoform X1 [KO:K00472] [EC:1.14.11.2]
121922458  CKMT2; creatine kinase S-type, mitochondrial [KO:K00933] [EC:2.7.3.2]
121923958  PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [KO:K00286] [EC:1.5.1.2]
121924872  P4HA3; prolyl 4-hydroxylase subunit alpha-3 isoform X1 [KO:K00472] [EC:1.14.11.2]
121925010  OAT; ornithine aminotransferase, mitochondrial [KO:K00819] [EC:2.6.1.13]
121925301  ALDH18A1; delta-1-pyrroline-5-carboxylate synthase isoform X1 [KO:K12657] [EC:2.7.2.11 1.2.1.41]
121925421  P4HA1; prolyl 4-hydroxylase subunit alpha-1 isoform X1 [KO:K00472] [EC:1.14.11.2]
121925515  [KO:K00274] [EC:1.4.3.4]
121925720  [KO:K00274] [EC:1.4.3.4]
121926128  HOGA1; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial [KO:K18123] [EC:4.1.3.16]
121926434  SAT1; diamine acetyltransferase 1 isoform X1 [KO:K00657] [EC:2.3.1.57]
121926583  GOT1; aspartate aminotransferase, cytoplasmic [KO:K14454] [EC:2.6.1.1]
121926744  SMS; spermine synthase isoform X1 [KO:K00802] [EC:2.5.1.22]
121927300  [KO:K00274] [EC:1.4.3.4]
121927603  [KO:K05604] [EC:3.4.13.20]
121927606  [KO:K08660] [EC:3.4.13.18]
121929230  [KO:K00149] [EC:1.2.1.47 1.2.1.3]
121929460  PYCR3; pyrroline-5-carboxylate reductase 3 isoform X1 [KO:K00286] [EC:1.5.1.2]
121929703  [KO:K08660] [EC:3.4.13.18]
121930467  SMOX; spermine oxidase isoform X1 [KO:K12259] [EC:1.5.3.16 1.5.3.-]
121931394  LAP3; cytosol aminopeptidase isoform X1 [KO:K11142] [EC:3.4.11.1 3.4.11.5]
121931884  L3HYPDH; trans-3-hydroxy-L-proline dehydratase isoform X1 [KO:K18384] [EC:4.2.1.77]
121932448  ALDH16A1; LOW QUALITY PROTEIN: aldehyde dehydrogenase family 16 member A1 [KO:K00128] [EC:1.2.1.3]
121932558  [KO:K00657] [EC:2.3.1.57]
121932643  [KO:K00933] [EC:2.7.3.2]
121932668  PRODH2; hydroxyproline dehydrogenase [KO:K11394] [EC:1.5.5.3]
121932802  AOC1; amiloride-sensitive amine oxidase [copper-containing] [KO:K11182] [EC:1.4.3.22]
121934099  [KO:K00657] [EC:2.3.1.57]
121934101  SAT2; thialysine N-epsilon-acetyltransferase isoform X1 [KO:K00657] [EC:2.3.1.57]
121934742  GOT1L1; putative aspartate aminotransferase, cytoplasmic 2 [KO:K14454] [EC:2.6.1.1]
121934839  [KO:K00657] [EC:2.3.1.57]
121934922  CKB; creatine kinase B-type isoform X1 [KO:K00933] [EC:2.7.3.2]
121934954  NOS3; nitric oxide synthase, endothelial isoform X1 [KO:K13242] [EC:1.14.13.39]
121935179  GATM; glycine amidinotransferase, mitochondrial [KO:K00613] [EC:2.1.4.1]
121936130  ALDH4A1; LOW QUALITY PROTEIN: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [KO:K00294] [EC:1.2.1.88]
121936141  SRM; spermidine synthase [KO:K00797] [EC:2.5.1.16]
121936231  AGMAT; agmatinase, mitochondrial [KO:K27001]
121936629  SATL1; spermidine/spermine N(1)-acetyltransferase-like protein 1 [KO:K00657] [EC:2.3.1.57]
121937122  GAMT; guanidinoacetate N-methyltransferase [KO:K00542] [EC:2.1.1.2]
Compound
C00012  Peptide
C00019  S-Adenosyl-L-methionine
C00022  Pyruvate
C00025  L-Glutamate
C00048  Glyoxylate
C00062  L-Arginine
C00077  L-Ornithine
C00086  Urea
C00134  Putrescine
C00148  L-Proline
C00179  Agmatine
C00213  Sarcosine
C00223  p-Coumaroyl-CoA
C00300  Creatine
C00315  Spermidine
C00334  4-Aminobutanoate
C00406  Feruloyl-CoA
C00431  5-Aminopentanoate
C00436  N-Carbamoylputrescine
C00441  L-Aspartate 4-semialdehyde
C00533  Nitric oxide
C00555  4-Aminobutyraldehyde
C00581  Guanidinoacetate
C00750  Spermine
C00763  D-Proline
C00791  Creatinine
C00884  Homocarnosine
C00986  1,3-Diaminopropane
C01035  4-Guanidinobutanoate
C01043  N-Carbamoylsarcosine
C01110  5-Amino-2-oxopentanoic acid
C01137  S-Adenosylmethioninamine
C01157  Hydroxyproline
C01165  L-Glutamate 5-semialdehyde
C01250  N-Acetyl-L-glutamate 5-semialdehyde
C01682  Nopaline
C02305  Phosphocreatine
C02565  N-Methylhydantoin
C02647  4-Guanidinobutanal
C02714  N-Acetylputrescine
C02946  4-Acetamidobutanoate
C03078  4-Guanidinobutanamide
C03166  Phosphoguanidinoacetate
C03287  L-Glutamyl 5-phosphate
C03296  N2-Succinyl-L-arginine
C03375  Norspermidine
C03415  N2-Succinyl-L-ornithine
C03564  1-Pyrroline-2-carboxylate
C03771  5-Guanidino-2-oxopentanoate
C03912  (S)-1-Pyrroline-5-carboxylate
C04137  Octopine
C04281  L-1-Pyrroline-3-hydroxy-5-carboxylate
C05147  trans-3-Hydroxy-L-proline
C05931  N-Succinyl-L-glutamate
C05932  N-Succinyl-L-glutamate 5-semialdehyde
C05933  N(omega)-Hydroxyarginine
C05936  N4-Acetylaminobutanal
C05938  L-4-Hydroxyglutamate semialdehyde
C05945  L-Arginine phosphate
C05946  (4R)-4-Hydroxy-2-oxoglutarate
C05947  L-erythro-4-Hydroxyglutamate
C10497  Feruloylputrescine
C15699  gamma-L-Glutamylputrescine
C15700  gamma-Glutamyl-gamma-aminobutyraldehyde
C15767  4-(L-gamma-Glutamylamino)butanoate
C18172  Carboxyspermidine
C18174  Carboxynorspermidine
C18326  p-Coumaroylputrescine
C19706  cis-3-Hydroxy-L-proline
C20560  N1-(3-Aminopropyl)agmatine
C22886  N1-[(S)-3-amino-3-carboxypropyl]agmatine
Reference
PMID:5288244
  Authors
Haake P, Allen GW.
  Title
Studies on phosphorylation by phosphoroguanidinates. The mechanism of action of creatine: ATP transphosphorylase (creatine kinase).
  Journal
Proc Natl Acad Sci U S A 68:2691-3 (1971)
DOI:10.1073/pnas.68.11.2691
Reference
PMID:16499623
  Authors
Kurihara S, Oda S, Kumagai H, Suzuki H.
  Title
Gamma-glutamyl-gamma-aminobutyrate hydrolase in the putrescine utilization pathway of Escherichia coli K-12.
  Journal
FEMS Microbiol Lett 256:318-23 (2006)
DOI:10.1111/j.1574-6968.2006.00137.x
Reference
PMID:15590624
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
Related
pathway
sund00020  Citrate cycle (TCA cycle)
sund00220  Arginine biosynthesis
sund00250  Alanine, aspartate and glutamate metabolism
sund00260  Glycine, serine and threonine metabolism
sund00270  Cysteine and methionine metabolism
sund00310  Lysine degradation
sund00410  beta-Alanine metabolism
sund00470  D-Amino acid metabolism
sund00480  Glutathione metabolism
sund00630  Glyoxylate and dicarboxylate metabolism
sund00650  Butanoate metabolism
sund00770  Pantothenate and CoA biosynthesis
KO pathway
ko00330   

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