KEGG   PATHWAY: svio00230
Entry
svio00230                   Pathway                                
Name
Purine metabolism - Streptomyces violascens
Class
Metabolism; Nucleotide metabolism
Pathway map
svio00230  Purine metabolism
svio00230

Module
svio_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:svio00230]
svio_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:svio00230]
svio_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:svio00230]
svio_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:svio00230]
svio_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:svio00230]
svio_M00546  Purine degradation, xanthine => urea [PATH:svio00230]
svio_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:svio00230]
Other DBs
GO: 0006163 0042278
Organism
Streptomyces violascens [GN:svio]
Gene
HWN34_28160  alpha-D-glucose phosphate-specific phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
HWN34_10995  ribose-phosphate diphosphokinase [KO:K00948] [EC:2.7.6.1]
HWN34_14635  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
HWN34_14715  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
HWN34_19605  phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
HWN34_14645  purL; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269] [EC:6.3.5.3]
HWN34_14655  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264] [EC:6.3.5.3]
HWN34_14650  purQ; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265] [EC:6.3.5.3 3.5.1.2]
HWN34_14630  phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
HWN34_10485  5-(carboxyamino)imidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
HWN34_10480  purE; 5-(carboxyamino)imidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
HWN34_14700  phosphoribosylaminoimidazolesuccinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
HWN34_28000  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
HWN34_19610  purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
HWN34_26960  adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
HWN34_16925  5'-nucleotidase C-terminal domain-containing protein [KO:K01081] [EC:3.1.3.5]
HWN34_09435  HAD family hydrolase [KO:K02566] [EC:3.1.3.5]
HWN34_20280  purine-nucleoside phosphorylase [KO:K03783] [EC:2.4.2.1]
HWN34_24240  pgeF; peptidoglycan editing factor PgeF [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
HWN34_17470  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
HWN34_19280  guaB; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
HWN34_19285  GuaB3 family IMP dehydrogenase-related protein [KO:K00088] [EC:1.1.1.205]
HWN34_21865  ndk; nucleoside-diphosphate kinase [KO:K00940] [EC:2.7.4.6]
HWN34_09575  rdgB; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase [KO:K01519] [EC:3.6.1.66]
HWN34_00345  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
HWN34_03745  xanthine dehydrogenase family protein molybdopterin-binding subunit [KO:K11177] [EC:1.17.1.4]
HWN34_00350  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
HWN34_03750  xanthine dehydrogenase family protein subunit M [KO:K11178] [EC:1.17.1.4]
HWN34_00355  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
HWN34_03755  2Fe-2S iron-sulfur cluster binding domain-containing protein [KO:K13483]
HWN34_19360  guaA; glutamine-hydrolyzing GMP synthase [KO:K01951] [EC:6.3.5.2]
HWN34_27210  GuaB1 family IMP dehydrogenase-related protein [KO:K26110] [EC:1.7.1.7]
HWN34_27125  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
HWN34_05975  vitamin B12-dependent ribonucleotide reductase [KO:K00525] [EC:1.17.4.1]
HWN34_08565  ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
HWN34_08570  ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
HWN34_22650  deoxyguanosinetriphosphate triphosphohydrolase [KO:K01129] [EC:3.1.5.1]
HWN34_06035  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HWN34_26965  bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
HWN34_10695  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HWN34_17825  Ppx/GppA family phosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
HWN34_13485  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HWN34_20345  adenylate/guanylate cyclase domain-containing protein [KO:K01768] [EC:4.6.1.1]
HWN34_13490  CYTH domain-containing protein [KO:K05873] [EC:4.6.1.1]
HWN34_16425  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
HWN34_23855  carbohydrate kinase family protein [KO:K00856] [EC:2.7.1.20]
HWN34_18755  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
HWN34_20175  adenosine deaminase [KO:K01488] [EC:3.5.4.4]
HWN34_22170  adenosine deaminase [KO:K21053] [EC:3.5.4.2]
HWN34_24585  5'-nucleotidase C-terminal domain-containing protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
HWN34_18995  adenylate kinase [KO:K00939] [EC:2.7.4.3]
HWN34_26885  HIT domain-containing protein [KO:K19710] [EC:2.7.7.53]
HWN34_04265  cysC; adenylyl-sulfate kinase [KO:K00860] [EC:2.7.1.25]
HWN34_04275  50S ribosome-binding GTPase [KO:K00956] [EC:2.7.7.4]
HWN34_04270  cysD; sulfate adenylyltransferase subunit CysD [KO:K00957] [EC:2.7.7.4]
HWN34_03870  pucL; urate oxidase [KO:K00365] [EC:1.7.3.3]
HWN34_03875  uraH; hydroxyisourate hydrolase [KO:K07127] [EC:3.5.2.17]
HWN34_03880  uraD; 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
HWN34_19920  2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase [KO:K16840] [EC:4.1.1.97]
HWN34_03725  allB; allantoinase AllB [KO:K01466] [EC:3.5.2.5]
HWN34_21710  alc; allantoicase [KO:K01477] [EC:3.5.3.4]
HWN34_07185  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HWN34_22520  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HWN34_28100  urease subunit alpha [KO:K01428] [EC:3.5.1.5]
HWN34_22525  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
HWN34_28095  urease subunit beta [KO:K01429] [EC:3.5.1.5]
HWN34_22530  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HWN34_28090  urease subunit gamma [KO:K01430] [EC:3.5.1.5]
HWN34_07190  urease subunit beta [KO:K14048] [EC:3.5.1.5]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
svio00030  Pentose phosphate pathway
svio00220  Arginine biosynthesis
svio00250  Alanine, aspartate and glutamate metabolism
svio00260  Glycine, serine and threonine metabolism
svio00340  Histidine metabolism
svio00630  Glyoxylate and dicarboxylate metabolism
svio00730  Thiamine metabolism
svio00740  Riboflavin metabolism
svio00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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