KEGG   PATHWAY: tgt00564
Entry
tgt00564                    Pathway                                
Name
Glycerophospholipid metabolism - Tinamus guttatus (white-throated tinamou)
Class
Metabolism; Lipid metabolism
Pathway map
tgt00564  Glycerophospholipid metabolism
tgt00564

Module
tgt_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:tgt00564]
tgt_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:tgt00564]
tgt_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:tgt00564]
Other DBs
GO: 0006650
Organism
Tinamus guttatus (white-throated tinamou) [GN:tgt]
Gene
104564490  CDS1; phosphatidate cytidylyltransferase 1 [KO:K00981] [EC:2.7.7.41]
104564686  MBOAT1; lysophospholipid acyltransferase 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
104564802  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
104564878  PCYT2; ethanolamine-phosphate cytidylyltransferase [KO:K00967] [EC:2.7.7.14]
104564896  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
104564963  CRLS1; cardiolipin synthase [KO:K08744] [EC:2.7.8.41]
104565214  [KO:K01047] [EC:3.1.1.4]
104565674  LPCAT3; lysophospholipid acyltransferase 5 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
104565797  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
104565920  [KO:K16860] [EC:3.1.4.4]
104566092  PGS1; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [KO:K00995] [EC:2.7.8.5]
104566121  PPAP2B; lipid phosphate phosphohydrolase 3 [KO:K01080] [EC:3.1.3.4]
104566403  [KO:K13506] [EC:2.3.1.15]
104566405  AGPAT9; glycerol-3-phosphate acyltransferase 3 [KO:K13506] [EC:2.3.1.15]
104566957  GPAM; glycerol-3-phosphate acyltransferase 1, mitochondrial [KO:K00629] [EC:2.3.1.15]
104566969  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
104567578  PLA2G10; group 10 secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104567953  PLA2G12B; group XIIB secretory phospholipase A2-like protein [KO:K01047] [EC:3.1.1.4]
104568368  [KO:K01115] [EC:3.1.4.4]
104568545  LPIN3; phosphatidate phosphatase LPIN3 [KO:K15728] [EC:3.1.3.4]
104568819  PNPLA7; patatin-like phospholipase domain-containing protein 7 [KO:K14676] [EC:3.1.1.5]
104569124  SAMD8; sphingomyelin synthase-related protein 1 [KO:K22697] [EC:2.7.8.48 3.1.4.62]
104569385  GNPAT; LOW QUALITY PROTEIN: dihydroxyacetone phosphate acyltransferase [KO:K00649] [EC:2.3.1.42]
104569899  [KO:K00901] [EC:2.7.1.107]
104570720  PLA2G4E; LOW QUALITY PROTEIN: cytosolic phospholipase A2 epsilon [KO:K16342] [EC:3.1.1.4]
104570805  DGKK; LOW QUALITY PROTEIN: diacylglycerol kinase kappa [KO:K00901] [EC:2.7.1.107]
104570831  [KO:K00993] [EC:2.7.8.1]
104570888  [KO:K13510] [EC:2.3.1.23 2.3.1.67]
104571626  AGPAT3; 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma [KO:K13523] [EC:2.3.1.51 2.3.1.-]
104571877  [KO:K16342] [EC:3.1.1.4]
104572155  GPD1L; glycerol-3-phosphate dehydrogenase 1-like protein [KO:K00006] [EC:1.1.1.8]
104572236  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
104572318  [KO:K16342] [EC:3.1.1.4]
104572319  [KO:K16342] [EC:3.1.1.4]
104572320  [KO:K16342] [EC:3.1.1.4]
104572321  [KO:K16342] [EC:3.1.1.4]
104572349  GPD2; glycerol-3-phosphate dehydrogenase, mitochondrial [KO:K00111] [EC:1.1.5.3]
104572438  PCYT1A; choline-phosphate cytidylyltransferase A [KO:K00968] [EC:2.7.7.15]
104572763  PLD3; phospholipase D3 [KO:K16860] [EC:3.1.4.4]
104573193  [KO:K00901] [EC:2.7.1.107]
104573399  AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [KO:K13523] [EC:2.3.1.51 2.3.1.-]
104573557  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
104573981  PCYT1B; choline-phosphate cytidylyltransferase B [KO:K00968] [EC:2.7.7.15]
104574308  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
104574433  PLA2G15; group XV phospholipase A2 [KO:K06129] [EC:3.1.1.5]
104574486  AGPAT2; 1-acyl-sn-glycerol-3-phosphate acyltransferase beta [KO:K13509] [EC:2.3.1.51]
104574541  [KO:K16342] [EC:3.1.1.4]
104574542  [KO:K16342] [EC:3.1.1.4]
104574664  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
104574810  AGPAT6; LOW QUALITY PROTEIN: glycerol-3-phosphate acyltransferase 6 [KO:K13506] [EC:2.3.1.15]
104574912  [KO:K00901] [EC:2.7.1.107]
104575031  LPIN2; phosphatidate phosphatase LPIN2 [KO:K15728] [EC:3.1.3.4]
104575058  LYPLA1; acyl-protein thioesterase 1 [KO:K06128] [EC:3.1.1.5]
104575187  GPD1; glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [KO:K00006] [EC:1.1.1.8]
104575432  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
104575910  GPCPD1; glycerophosphocholine phosphodiesterase GPCPD1 [KO:K18695] [EC:3.1.4.2]
104576393  PLA2G12A; group XIIA secretory phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104576613  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
104576674  PPAPDC1B; phosphatidate phosphatase PPAPDC1B [KO:K18693] [EC:3.6.1.75 3.1.3.4]
104576749  PLA2G6; 85/88 kDa calcium-independent phospholipase A2 [KO:K16343] [EC:3.1.1.4]
104576791  [KO:K16342] [EC:3.1.1.4]
104576853  CEPT1; choline/ethanolaminephosphotransferase 1 isoform X1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
104577035  LCAT; phosphatidylcholine-sterol acyltransferase isoform X1 [KO:K00650] [EC:2.3.1.43]
104577267  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
104577350  LPIN1; phosphatidate phosphatase LPIN1 isoform X1 [KO:K15728] [EC:3.1.3.4]
104577714  PLA2G4B; cytosolic phospholipase A2 beta [KO:K16342] [EC:3.1.1.4]
104577843  CDS2; phosphatidate cytidylyltransferase 2 [KO:K00981] [EC:2.7.7.41]
104578064  EPT1; ethanolaminephosphotransferase 1 [KO:K00993] [EC:2.7.8.1]
104578154  [KO:K13509] [EC:2.3.1.51]
104578357  CHPT1; cholinephosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
104578482  MBOAT2; lysophospholipid acyltransferase 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
104578537  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
104578541  SGMS2; phosphatidylcholine:ceramide cholinephosphotransferase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
104578628  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
104578787  LYPLA2; acyl-protein thioesterase 2 [KO:K06130] [EC:3.1.1.5]
104578995  ETNK1; ethanolamine kinase 1 isoform X1 [KO:K00894] [EC:2.7.1.82]
104579125  PPAP2A; lipid phosphate phosphohydrolase 1 [KO:K01080] [EC:3.1.3.4]
104580026  [KO:K00006] [EC:1.1.1.8]
104580095  PPAP2C; lipid phosphate phosphohydrolase 2 [KO:K01080] [EC:3.1.3.4]
104580144  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
104580286  AGPAT1; 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [KO:K13509] [EC:2.3.1.51]
104580484  [KO:K01047] [EC:3.1.1.4]
104580524  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
104580553  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
104580664  LPGAT1; acyl-CoA:lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
104581110  PISD; phosphatidylserine decarboxylase proenzyme isoform X1 [KO:K01613] [EC:4.1.1.65]
104581140  PLA2G1B; LOW QUALITY PROTEIN: phospholipase A2 [KO:K01047] [EC:3.1.1.4]
104581179  AGPAT5; 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon [KO:K19007] [EC:2.3.1.51]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
tgt00010  Glycolysis / Gluconeogenesis
tgt00260  Glycine, serine and threonine metabolism
tgt00561  Glycerolipid metabolism
tgt00562  Inositol phosphate metabolism
tgt00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
tgt00565  Ether lipid metabolism
tgt00620  Pyruvate metabolism
KO pathway
ko00564   

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