KEGG   PATHWAY: vce00230
Entry
vce00230                    Pathway                                
Name
Purine metabolism - Vibrio cholerae O1 2010EL-1786
Class
Metabolism; Nucleotide metabolism
Pathway map
vce00230  Purine metabolism
vce00230

Module
vce_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:vce00230]
vce_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:vce00230]
vce_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:vce00230]
vce_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:vce00230]
vce_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:vce00230]
Other DBs
GO: 0006163 0042278
Organism
Vibrio cholerae O1 2010EL-1786 [GN:vce]
Gene
Vch1786_II0453  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Vch1786_I1926  ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
Vch1786_I2215  nudE; ADP-ribose diphosphatase NudE [KO:K08312] [EC:3.6.1.-]
Vch1786_I1838  phosphopentomutase [KO:K01839] [EC:5.4.2.7]
Vch1786_I1588  phosphoglucomutase [KO:K01835] [EC:5.4.2.2]
Vch1786_I1671  prsA; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Vch1786_I0509  amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Vch1786_I2558  phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Vch1786_I1721  purN; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Vch1786_I0734  purT; phosphoribosylglycinamide formyltransferase 2 [KO:K08289] [EC:6.3.1.21]
Vch1786_I0375  purL; phosphoribosylformylglycinamidine synthase [KO:K01952] [EC:6.3.5.3]
Vch1786_I1720  purM; phosphoribosylaminoimidazole synthetase [KO:K01933] [EC:6.3.3.1]
Vch1786_I2361  purK; phosphoribosylaminoimidazole carboxylase ATPase subunit [KO:K01589] [EC:6.3.4.18]
Vch1786_I2360  purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit [KO:K01588] [EC:5.4.99.18]
Vch1786_I0694  phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Vch1786_I0630  adenylosuccinate lyase [KO:K01756] [EC:4.3.2.2]
Vch1786_I2559  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Vch1786_I0556  apt; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Vch1786_II0234  5'-nucleotidase [KO:K01081] [EC:3.1.3.5]
Vch1786_I1662  ushA; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor [KO:K11751] [EC:3.1.3.5 3.6.1.45]
Vch1786_I2837  surE; stationary phase survival protein SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Vch1786_II0491  gsk-2; inosine-guanosine kinase [KO:K00892] [EC:2.7.1.73]
Vch1786_I0633  inosine kinase [KO:K00892] [EC:2.7.1.73]
Vch1786_I1837  deoD; purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Vch1786_II0848  purine nucleoside phosphorylase [KO:K03784] [EC:2.4.2.1]
Vch1786_II0656  hypothetical protein [KO:K09913] [EC:2.4.2.1 2.4.2.2]
Vch1786_I0213  conserved hypothetical protein [KO:K05810] [EC:2.4.2.1 2.4.2.28 3.5.4.4]
Vch1786_I2896  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Vch1786_I0273  guaB; inosine 5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Vch1786_I0262  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Vch1786_I2777  nucleoside-triphosphatase [KO:K01519] [EC:3.6.1.66]
Vch1786_I1769  gpt; xanthine-guanine phosphoribosyltransferase [KO:K00769] [EC:2.4.2.22]
Vch1786_I0274  GMP synthase (glutamine-hydrolysing) [KO:K01951] [EC:6.3.5.2]
Vch1786_II0991  guaC; guanosine 5'-monophosphate oxidoreductase [KO:K00364] [EC:1.7.1.7]
Vch1786_I2202  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
Vch1786_I0760  ribonucleoside-diphosphate reductase alpha chain [KO:K00525] [EC:1.17.4.1]
Vch1786_I0759  nrdB; ribonucleotide-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
Vch1786_II0201  ribonucleoside-triphosphate reductase [KO:K21636] [EC:1.1.98.6]
Vch1786_I1471  dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
Vch1786_I1470  5'-nucleotidase [KO:K08722] [EC:3.1.3.89]
Vch1786_I2204  spoT; guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Vch1786_I0230  exopolyphosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Vch1786_I2588  guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Vch1786_I1943  GTP pyrophosphokinase [KO:K00951] [EC:2.7.6.5]
Vch1786_I2287  cyaA; adenylate cyclase [KO:K05851] [EC:4.6.1.1]
Vch1786_I2097  adenylosuccinate synthase [KO:K01939] [EC:6.3.4.4]
Vch1786_I2245  add; adenosine deaminase [KO:K01488] [EC:3.5.4.4]
Vch1786_I0405  hypothetical protein [KO:K06966] [EC:3.2.2.10 3.2.2.-]
Vch1786_I1906  2',3'-cyclic-nucleotide 2'-phosphodiesterase [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Vch1786_I2057  cpdB; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Vch1786_I0489  adk; adenylate kinase [KO:K00939] [EC:2.7.4.3]
Vch1786_I1942  mazG; nucleoside triphosphate pyrophosphohydrolase [KO:K04765] [EC:3.6.1.9]
Vch1786_I1924  cpdA; cyclic 3',5'-adenosine monophosphate phosphodiesterase [KO:K03651] [EC:3.1.4.53]
Vch1786_I2751  apaH; diadenosine tetraphosphatase [KO:K01525] [EC:3.6.1.41]
Vch1786_I2053  cysC; adenylylsulfate kinase [KO:K00860] [EC:2.7.1.25]
Vch1786_I2054  cysN; sulfate adenylyltransferase subunit 1 [KO:K00956] [EC:2.7.7.4]
Vch1786_I2055  cysD; sulfate adenylyltransferase subunit 2 [KO:K00957] [EC:2.7.7.4]
Vch1786_II0246  gamma-glutamyltranspeptidase [KO:K22602] [EC:3.5.1.126]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
vce00030  Pentose phosphate pathway
vce00220  Arginine biosynthesis
vce00250  Alanine, aspartate and glutamate metabolism
vce00260  Glycine, serine and threonine metabolism
vce00340  Histidine metabolism
vce00630  Glyoxylate and dicarboxylate metabolism
vce00730  Thiamine metabolism
vce00740  Riboflavin metabolism
vce00790  Folate biosynthesis
KO pathway
ko00230   
LinkDB

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