KEGG   PATHWAY: vum00053
Entry
vum00053                    Pathway                                
Name
Ascorbate and aldarate metabolism - Vigna umbellata (ricebean)
Class
Metabolism; Carbohydrate metabolism
Pathway map
vum00053  Ascorbate and aldarate metabolism
vum00053

Module
vum_M00114  Ascorbate biosynthesis, plants, fructose-6P => ascorbate [PATH:vum00053]
Other DBs
GO: 0019852 0019577 0019572
Organism
Vigna umbellata (ricebean) [GN:vum]
Gene
124820544  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
124834939  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
124834940  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
124846267  UDP-glucose 6-dehydrogenase 1-like [KO:K00012] [EC:1.1.1.22]
124835046  UDP-glucose 6-dehydrogenase 1 [KO:K00012] [EC:1.1.1.22]
124826237  UDP-glucose 6-dehydrogenase 4-like [KO:K00012] [EC:1.1.1.22]
124826520  UDP-sugar pyrophosphorylase 1 [KO:K12447] [EC:2.7.7.64]
124841870  glucuronokinase 1-like [KO:K16190] [EC:2.7.1.43]
124820246  inositol oxygenase 2-like isoform X1 [KO:K00469] [EC:1.13.99.1]
124820248  inositol oxygenase 2-like isoform X1 [KO:K00469] [EC:1.13.99.1]
124829774  inositol oxygenase 1-like [KO:K00469] [EC:1.13.99.1]
124820259  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
124823855  aldose reductase isoform X1 [KO:K00002] [EC:1.1.1.2]
124825711  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
124839871  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
124830344  NADPH-dependent aldo-keto reductase, chloroplastic-like isoform X1 [KO:K00002] [EC:1.1.1.2]
124830851  NADPH-dependent aldo-keto reductase, chloroplastic-like [KO:K00002] [EC:1.1.1.2]
124846202  L-gulonolactone oxidase 3-like [KO:K00103] [EC:1.1.3.8]
124841793  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
124843112  L-gulonolactone oxidase 2-like [KO:K00103] [EC:1.1.3.8]
124843113  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
124843114  probable L-gulonolactone oxidase 6 [KO:K00103] [EC:1.1.3.8]
124845500  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
124845501  GDP-mannose 3,5-epimerase 2 [KO:K10046] [EC:5.1.3.18 5.1.3.-]
124819469  GDP-mannose 3,5-epimerase 2-like [KO:K10046] [EC:5.1.3.18 5.1.3.-]
124833993  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
124828672  GDP-L-galactose phosphorylase 1-like [KO:K14190] [EC:2.7.7.69]
124836571  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
124839448  inositol-phosphate phosphatase-like [KO:K10047] [EC:3.1.3.25 3.1.3.93]
124824591  bifunctional phosphatase IMPL2, chloroplastic [KO:K18649] [EC:3.1.3.25 3.1.3.93 3.1.3.15]
124824695  L-galactose dehydrogenase [KO:K17744] [EC:1.1.1.316]
124840132  L-galactono-1,4-lactone dehydrogenase, mitochondrial [KO:K00225] [EC:1.3.2.3]
124834347  UDP-glucuronate 4-epimerase 3 [KO:K08679] [EC:5.1.3.6]
124827645  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
124819810  UDP-glucuronate 4-epimerase 1 [KO:K08679] [EC:5.1.3.6]
124828932  UDP-glucuronate 4-epimerase 5 [KO:K08679] [EC:5.1.3.6]
124833440  UDP-glucuronate 4-epimerase 6 [KO:K08679] [EC:5.1.3.6]
124822353  monodehydroascorbate reductase [KO:K08232] [EC:1.6.5.4]
124848978  monodehydroascorbate reductase 4, peroxisomal [KO:K08232] [EC:1.6.5.4]
124827297  monodehydroascorbate reductase, chloroplastic/mitochondrial [KO:K08232] [EC:1.6.5.4]
124823125  probable L-ascorbate peroxidase 6, chloroplastic/mitochondrial isoform X1 [KO:K00434] [EC:1.11.1.11]
124835734  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
124848319  probable L-ascorbate peroxidase 3, peroxisomal [KO:K00434] [EC:1.11.1.11]
124848328  L-ascorbate peroxidase 3-like [KO:K00434] [EC:1.11.1.11]
124849005  putative L-ascorbate peroxidase 6 isoform X1 [KO:K00434] [EC:1.11.1.11]
124838303  L-ascorbate peroxidase, cytosolic [KO:K00434] [EC:1.11.1.11]
124840963  L-ascorbate peroxidase 3 [KO:K00434] [EC:1.11.1.11]
124832730  glutathione S-transferase DHAR2 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
124834120  glutathione S-transferase DHAR3, chloroplastic-like [KO:K21888] [EC:1.8.5.1 2.5.1.18]
124846323  uncharacterized protein LOC124846323 [KO:K21888] [EC:1.8.5.1 2.5.1.18]
124820542  LOW QUALITY PROTEIN: L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
124834194  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
124822518  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
124834791  L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
124848176  LOW QUALITY PROTEIN: L-ascorbate oxidase-like [KO:K00423] [EC:1.10.3.3]
124838591  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
124838592  L-ascorbate oxidase homolog [KO:K00423] [EC:1.10.3.3]
124832332  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
124833004  aldehyde dehydrogenase family 3 member H1-like isoform X1 [KO:K00128] [EC:1.2.1.3]
124834421  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
124823127  aldehyde dehydrogenase family 3 member H1-like [KO:K00128] [EC:1.2.1.3]
124848699  benzaldehyde dehydrogenase, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
124825196  aldehyde dehydrogenase family 3 member F1-like [KO:K00128] [EC:1.2.1.3]
124838651  benzaldehyde dehydrogenase, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
124839476  aldehyde dehydrogenase family 2 member B4, mitochondrial-like [KO:K00128] [EC:1.2.1.3]
124829944  benzaldehyde dehydrogenase, mitochondrial-like isoform X1 [KO:K00128] [EC:1.2.1.3]
124819873  aldehyde dehydrogenase family 3 member F1 [KO:K00128] [EC:1.2.1.3]
124819683  LOW QUALITY PROTEIN: aldehyde dehydrogenase family 7 member A1 [KO:K14085] [EC:1.2.1.31 1.2.1.8 1.2.1.3]
Compound
C00022  Pyruvate
C00026  2-Oxoglutarate
C00029  UDP-glucose
C00072  Ascorbate
C00096  GDP-mannose
C00137  myo-Inositol
C00167  UDP-glucuronate
C00191  D-Glucuronate
C00216  D-Arabinose
C00231  D-Xylulose 5-phosphate
C00259  L-Arabinose
C00333  D-Galacturonate
C00433  2,5-Dioxopentanoate
C00545  L-Arabinonate
C00558  D-Tagaturonate
C00617  UDP-D-galacturonate
C00618  3-Dehydro-L-gulonate
C00652  D-Arabinono-1,4-lactone
C00679  5-Dehydro-4-deoxy-D-glucarate
C00684  2-Dehydro-3-deoxy-L-arabinonate
C00800  L-Gulonate
C00818  D-Glucarate
C00878  D-Arabinonate
C00879  D-Galactarate
C01040  L-Gulono-1,4-lactone
C01041  Monodehydroascorbate
C01101  L-Ribulose 5-phosphate
C01114  L-Arabinono-1,4-lactone
C01115  L-Galactono-1,4-lactone
C01146  2-Hydroxy-3-oxopropanoate
C01620  Threonate
C01825  L-Galactose
C02280  GDP-L-galactose
C02670  D-Glucuronolactone
C03033  beta-D-Glucuronoside
C03064  3-Dehydro-L-threonate
C03289  L-xylo-Hexulonolactone
C03291  L-Xylulose 5-phosphate
C03826  2-Dehydro-3-deoxy-D-xylonate
C03921  2-Dehydro-3-deoxy-D-glucarate
C04037  1-Phospho-alpha-D-galacturonate
C04575  (4R,5S)-4,5,6-Trihydroxy-2,3-dioxohexanoate
C05385  D-Glucuronate 1-phosphate
C05411  L-Xylonate
C05412  L-Lyxonate
C05422  Dehydroascorbate
C06316  Dehydro-D-arabinono-1,4-lactone
C14899  3-Dehydro-L-gulonate 6-phosphate
C15923  L-Gulose
C15924  L-Gulose 1-phosphate
C15925  GDP-L-gulose
C15926  beta-L-Galactose 1-phosphate
C15930  L-Galactonate
C16186  L-Ascorbate 6-phosphate
C20889  D-Galactaro-1,5-lactone
C20896  D-Galactaro-1,4-lactone
C21955  L-Galactono-1,5-lactone
Reference
PMID:17222174
  Authors
Linster CL, Van Schaftingen E
  Title
Vitamin C. Biosynthesis, recycling and degradation in mammals.
  Journal
FEBS J 274:1-22 (2007)
DOI:10.1111/j.1742-4658.2006.05607.x
Reference
PMID:15564123
  Authors
Valpuesta V, Botella MA.
  Title
Biosynthesis of L-ascorbic acid in plants: new pathways for an old antioxidant.
  Journal
Trends Plant Sci 9:573-7 (2004)
DOI:10.1016/j.tplants.2004.10.002
Reference
PMID:10517845
  Authors
Davey MW, Gilot C, Persiau G, Ostergaard J, Han Y, Bauw GC, Van Montagu MC.
  Title
Ascorbate biosynthesis in Arabidopsis cell suspension culture.
  Journal
Plant Physiol 121:535-43 (1999)
DOI:10.1104/pp.121.2.535
Reference
PMID:16595667
  Authors
Conklin PL, Gatzek S, Wheeler GL, Dowdle J, Raymond MJ, Rolinski S, Isupov M, Littlechild JA, Smirnoff N.
  Title
Arabidopsis thaliana VTC4 encodes L-galactose-1-P phosphatase, a plant ascorbic acid biosynthetic enzyme.
  Journal
J Biol Chem 281:15662-70 (2006)
DOI:10.1074/jbc.M601409200
Reference
PMID:17462988
  Authors
Linster CL, Gomez TA, Christensen KC, Adler LN, Young BD, Brenner C, Clarke SG.
  Title
Arabidopsis VTC2 Encodes a GDP-L-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants.
  Journal
J Biol Chem 282:18879-85 (2007)
DOI:10.1074/jbc.M702094200
Reference
PMID:14996803
  Authors
Campos E, Baldoma L, Aguilar J, Badia J.
  Title
Regulation of expression of the divergent ulaG and ulaABCDEF operons involved in LaAscorbate dissimilation in Escherichia coli.
  Journal
J Bacteriol 186:1720-8 (2004)
DOI:10.1128/JB.186.6.1720-1728.2004
Reference
PMID:12644495
  Authors
Zhang Z, Aboulwafa M, Smith MH, Saier MH Jr.
  Title
The ascorbate transporter of Escherichia coli.
  Journal
J Bacteriol 185:2243-50 (2003)
DOI:10.1128/JB.185.7.2243-2250.2003
Related
pathway
vum00020  Citrate cycle (TCA cycle)
vum00040  Pentose and glucuronate interconversions
vum00051  Fructose and mannose metabolism
vum00520  Amino sugar and nucleotide sugar metabolism
vum00630  Glyoxylate and dicarboxylate metabolism
KO pathway
ko00053   
LinkDB

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