KEGG    Network variation - CGAS-STING signaling
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ENTRYnt06520
NameCGAS-STING signaling
CategoryPathway view; Immune system
Pathwayhsa04623 Cytosolic DNA-sensing pathway
DiseaseH00290 Aicardi-Goutieres syndrome
Display drug-target relation   disease type
N00395    DNACGAScGAMPSTING1TBK1IRF3(IFNA,IFNB)
    SAVI       STING1*
N00569    UL41CGAS
N00570        ICP0STING1
N00396    HCMV     UL82STING1
N00946    Shigella   IpaJARF1STING1
N00947    Shigella       Ipa4.5TBK1
N00440    HIV         (Vpu,Vif,Vpr)IRF3
N01571    (TREX1,DNASE1,DNAS..DNA
    AGS1/SLE/CHBL1/RVCL TREX1*
    SLE DNASE1*
    SLEB16 DNASE1L3*
    AIPCS DNASE2*
N01572    RNASEH2DNA
    AGS4 RNASEH2A*
    AGS2 RNASEH2B*
    AGS3 RNASEH2C*
N01573    SAMHD1dNTP
    AGS5/CHBL2 SAMHD1*

Disease nameDisease category
SAVIH01746STING-associated vasculopathy with onset in infancyImmune system disease
HSVH00365Herpes simplex virus infectionViral infectious disease
HCMVH00368Cytomegalovirus infectionViral infectious disease
ShigellaH00299ShigellosisBacterial infectious disease
HIVH01563HIV infectionViral infectious disease
AGS1/SLE/CHBL1/RVCLH00290Aicardi-Goutieres syndromeImmune system disease
H00080Systemic lupus erythematosusImmune system disease
H00291Familial chilblain lupus (FCL)Immune system disease
H01000Retinal vasculopathy with cerebral leukodystrophyNervous system disease
SLEH00080Systemic lupus erythematosusImmune system disease
SLEB16H00080Systemic lupus erythematosusImmune system disease
AIPCSH02608Autoinflammatory-pancytopenia syndromeImmune system disease
AGS4H00290Aicardi-Goutieres syndromeImmune system disease
AGS2H00290Aicardi-Goutieres syndromeImmune system disease
AGS3H00290Aicardi-Goutieres syndromeImmune system disease
AGS5/CHBL2H00290Aicardi-Goutieres syndromeImmune system disease
H00291Familial chilblain lupus (FCL)Immune system disease