KEGG T01001: 2353

nt06110  MAPK signaling (virus)
nt06121  TLR signaling (virus)
nt06123  TNF signaling (virus)
nt06124  Chemokine signaling (virus)
nt06160  Human T-cell leukemia virus 1 (HTLV-1)
nt06161  Human immunodeficiency virus type 1 (HIV-1)
nt06162  Hepatitis B virus (HBV)
nt06164  Kaposi sarcoma-associated herpesvirus (KSHV)
nt06211  Other MAPK signaling
nt06224  CXCR signaling

Element

N00157

KSHV vGPCR to GNB/G-ERK signaling pathway

N00188

IL1-IL1R-JNK signaling pathway

N00189

KSHV K15 to JNK signaling pathway

N00438

TLR2/4-MAPK signaling pathway

N00439

HIV Nef to TLR2/4-MAPK signaling pathway

N00447

HIV Vpr/Tat to TNF-JNK signaling pathway

N00509

HTLV-1 Tax to SRF-mediated transcription

N00545

HBV HBx to ERK signaling pathway

N00547

HBV LHBs to PKC-ERK signaling pathway

N00551

HBV HBs to TLR2/4-MAPK signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    2353 (FOS)
   04668 TNF signaling pathway
    2353 (FOS)
   04024 cAMP signaling pathway
    2353 (FOS)
09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    2353 (FOS)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    2353 (FOS)
   04660 T cell receptor signaling pathway
    2353 (FOS)
   04658 Th1 and Th2 cell differentiation
    2353 (FOS)
   04659 Th17 cell differentiation
    2353 (FOS)
   04657 IL-17 signaling pathway
    2353 (FOS)
   04662 B cell receptor signaling pathway
    2353 (FOS)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    2353 (FOS)
   04917 Prolactin signaling pathway
    2353 (FOS)
   04921 Oxytocin signaling pathway
    2353 (FOS)
   04926 Relaxin signaling pathway
    2353 (FOS)
   04928 Parathyroid hormone synthesis, secretion and action
    2353 (FOS)
  09156 Nervous system
   04725 Cholinergic synapse
    2353 (FOS)
   04728 Dopaminergic synapse
    2353 (FOS)
  09158 Development
   04380 Osteoclast differentiation
    2353 (FOS)
  09159 Environmental adaptation
   04713 Circadian entrainment
    2353 (FOS)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    2353 (FOS)
   05231 Choline metabolism in cancer
    2353 (FOS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    2353 (FOS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    2353 (FOS)
   05224 Breast cancer
    2353 (FOS)
  09163 Immune disease
   05323 Rheumatoid arthritis
    2353 (FOS)
  09165 Substance dependence
   05031 Amphetamine addiction
    2353 (FOS)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    2353 (FOS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    2353 (FOS)
   05135 Yersinia infection
    2353 (FOS)
   05133 Pertussis
    2353 (FOS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    2353 (FOS)
   05170 Human immunodeficiency virus 1 infection
    2353 (FOS)
   05162 Measles
    2353 (FOS)
   05161 Hepatitis B
    2353 (FOS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    2353 (FOS)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    2353 (FOS)
   05142 Chagas disease (American trypanosomiasis)
    2353 (FOS)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    2353 (FOS)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2353 (FOS)
   04131 Membrane trafficking [BR:hsa04131]
    2353 (FOS)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    2353 (FOS)
Membrane trafficking [BR:hsa04131]
Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    2353 (FOS)

SSDB

Motif

Pfam:

bZIP_1 bZIP_2 bZIP_Maf Macoilin DUF3450 HALZ

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P01100(Tbio)

UniProt:

P01100 Q6FG41

LinkDB

Structure

PDB:

1A02 1FOS 1S9K

Position

14q24.3

AA seq 380 aa
MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANF
IPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRA
QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ
TEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFT
LPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYA
ADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRK
GSSSNEPSSDSLSSPTLLAL

NT seq 1143 nt +upstreamnt +downstreamnt
atgatgttctcgggcttcaacgcagactacgaggcgtcatcctcccgctgcagcagcgcg
tccccggccggggatagcctctcttactaccactcacccgcagactccttctccagcatg
ggctcgcctgtcaacgcgcaggacttctgcacggacctggccgtctccagtgccaacttc
attcccacggtcactgccatctcgaccagtccggacctgcagtggctggtgcagcccgcc
ctcgtctcctccgtggccccatcgcagaccagagcccctcaccctttcggagtccccgcc
ccctccgctggggcttactccagggctggcgttgtgaagaccatgacaggaggccgagcg
cagagcattggcaggaggggcaaggtggaacagttatctccagaagaagaagagaaaagg
agaatccgaagggaaaggaataagatggctgcagccaaatgccgcaaccggaggagggag
ctgactgatacactccaagcggagacagaccaactagaagatgagaagtctgctttgcag
accgagattgccaacctgctgaaggagaaggaaaaactagagttcatcctggcagctcac
cgacctgcctgcaagatccctgatgacctgggcttcccagaagagatgtctgtggcttcc
cttgatctgactgggggcctgccagaggttgccaccccggagtctgaggaggccttcacc
ctgcctctcctcaatgaccctgagcccaagccctcagtggaacctgtcaagagcatcagc
agcatggagctgaagaccgagccctttgatgacttcctgttcccagcatcatccaggccc
agtggctctgagacagcccgctccgtgccagacatggacctatctgggtccttctatgca
gcagactgggagcctctgcacagtggctccctggggatggggcccatggccacagagctg
gagcccctgtgcactccggtggtcacctgtactcccagctgcactgcttacacgtcttcc
ttcgtcttcacctaccccgaggctgactccttccccagctgtgcagctgcccaccgcaag
ggcagcagcagcaatgagccttcctctgactcgctcagctcacccacgctgctggccctg
tga

Homo sapiens (human): 2354

Entry

2354 CDS T01001

Gene name

FOSB, AP-1, G0S3, GOS3, GOSB

Definition

(RefSeq) FosB proto-oncogene, AP-1 transcription factor subunit

K09029

protein FosB

Organism

hsa Homo sapiens (human)

Pathway

hsa04380

Osteoclast differentiation

hsa04657

IL-17 signaling pathway

hsa05030

Cocaine addiction

hsa05031

Amphetamine addiction

hsa05034

Alcoholism

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    2354 (FOSB)
  09158 Development
   04380 Osteoclast differentiation
    2354 (FOSB)
09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    2354 (FOSB)
   05031 Amphetamine addiction
    2354 (FOSB)
   05034 Alcoholism
    2354 (FOSB)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2354 (FOSB)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    2354 (FOSB)

SSDB

Motif

Pfam:

bZIP_1 bZIP_2 bZIP_Maf DivIC DUF4407 DUF3450 DUF5082

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P53539(Tbio)

UniProt:

P53539 A0A024R0P6

LinkDB

Structure

PDB:

5VPE 5VPC 5VPB 5VPF 5VPD 5VPA

Position

19q13.32

AA seq 338 aa
MFQAFPGDYDSGSRCSSSPSAESQYLSSVDSFGSPPTAAASQECAGLGEMPGSFVPTVTA
ITTSQDLQWLVQPTLISSMAQSQGQPLASQPPVVDPYDMPGTSYSTPGMSGYSSGGASGS
GGPSTSGTTSGPGPARPARARPRRPREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELT
DRLQAETDQLEEEKAELESEIAELQKEKERLEFVLVAHKPGCKIPYEEGPGPGPLAEVRD
LPGSAPAKEDGFSWLLPPPPPPPLPFQTSQDAPPNLTASLFTHSEVQVLGDPFPVVNPSY
TSSFVLTCPEVSAFAGAQRTSGSDQPSDPLNSPSLLAL

NT seq 1017 nt +upstreamnt +downstreamnt
atgtttcaggctttccccggagactacgactccggctcccggtgcagctcctcaccctct
gccgagtctcaatatctgtcttcggtggactccttcggcagtccacccaccgccgccgcc
tcccaggagtgcgccggtctcggggaaatgcccggttccttcgtgcccacggtcaccgcg
atcacaaccagccaggacctccagtggcttgtgcaacccaccctcatctcttccatggcc
cagtcccaggggcagccactggcctcccagcccccggtcgtcgacccctacgacatgccg
ggaaccagctactccacaccaggcatgagtggctacagcagtggcggagcgagtggcagt
ggtgggccttccaccagcggaactaccagtgggcctgggcctgcccgcccagcccgagcc
cggcctaggagaccccgagaggagacgctcaccccagaggaagaggagaagcgaagggtg
cgccgggaacgaaataaactagcagcagctaaatgcaggaaccggcggagggagctgacc
gaccgactccaggcggagacagatcagttggaggaagaaaaagcagagctggagtcggag
atcgccgagctccaaaaggagaaggaacgtctggagtttgtgctggtggcccacaaaccg
ggctgcaagatcccctacgaagaggggcccgggccgggcccgctggcggaggtgagagat
ttgccgggctcagcaccggctaaggaagatggcttcagctggctgctgccgcccccgcca
ccaccgcccctgcccttccagaccagccaagacgcaccccccaacctgacggcttctctc
tttacacacagtgaagttcaagtcctcggcgaccccttccccgttgttaacccttcgtac
acttcttcgtttgtcctcacctgcccggaggtctccgcgttcgccggcgcccaacgcacc
agcggcagtgaccagccttccgatcccctgaactcgccctccctcctcgctctgtga

Homo sapiens (human): 2355

Entry

2355 CDS T01001

Gene name

FOSL2, FRA2

Definition

(RefSeq) FOS like 2, AP-1 transcription factor subunit

K09030

fos-like antigen 2

Organism

hsa Homo sapiens (human)

Pathway

hsa04380

Osteoclast differentiation

Brite

KEGG Orthology (KO) [BR:hsa00001]
09150 Organismal Systems
  09158 Development
   04380 Osteoclast differentiation
    2355 (FOSL2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    2355 (FOSL2)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    2355 (FOSL2)

SSDB

Motif

Pfam:

bZIP_1 bZIP_2 bZIP_Maf UPF0242 DUF5082 DUF4407

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P15408(Tbio)

UniProt:

P15408 Q9H5M2

LinkDB

Position

2p23.2

AA seq 326 aa
MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDL
QWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLS
PEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKL
EFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDK
AQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESC
SKAHRRSSSSGDQSSDSLNSPTLLAL

NT seq 981 nt +upstreamnt +downstreamnt
atgtaccaggattatcccgggaactttgacacctcgtcccggggcagcagcggctctcct
gcgcacgccgagtcctactccagcggcggcggcggccagcagaaattccgggtagatatg
cctggctcaggcagtgcattcatccccaccatcaacgccatcacgaccagccaggacctg
cagtggatggtgcagcccacagtgatcacctccatgtccaacccataccctcgctcgcac
ccctacagccccctgccgggcctggcctctgtccctggacacatggccctcccaagacct
ggcgtgatcaagaccattggcaccaccgtgggccgcaggaggagagatgagcagctgtct
cctgaagaggaggagaagcgtcgcatccggcgggagaggaacaagctggctgcagccaag
tgccggaaccgacgccgggagctgacagagaagctgcaggcggagacagaggagctggag
gaggagaagtcaggcctgcagaaggagattgctgagctgcagaaggagaaggagaagctg
gagttcatgttggtggctcacggcccagtgtgcaagattagccccgaggagcgccgatcg
cccccagcccctgggctgcagcccatgcgcagtgggggtggctcggtgggcgctgtagtg
gtgaaacaggagcccctggaagaggacagcccctcgtcctcgtcggcggggctggacaag
gcccagcgctctgtcatcaagcccatcagcattgctgggggcttctacggtgaggagccc
ctgcacacccccatcgtggtgacctccacacctgctgtcactccgggcacctcgaacctc
gtcttcacctatcctagcgtcctggagcaggagtcacccgcatctccctccgaatcctgc
tccaaggctcaccgcagaagcagtagcagcggggaccaatcatcagactccttgaactcc
cccactctgctggctctgtaa

Homo sapiens (human): 3725

Entry

3725 CDS T01001

Gene name

JUN, AP-1, AP1, c-Jun, p39

Definition

(RefSeq) Jun proto-oncogene, AP-1 transcription factor subunit

K04448

transcription factor AP-1

Organism

hsa Homo sapiens (human)

Pathway

hsa01522

Endocrine resistance

hsa04010

MAPK signaling pathway

hsa04012

ErbB signaling pathway

hsa04024

cAMP signaling pathway

hsa04137

Mitophagy - animal

hsa04210

Apoptosis

hsa04310

Wnt signaling pathway

hsa04380

Osteoclast differentiation

hsa04510

Focal adhesion

hsa04530

Tight junction

hsa04620

Toll-like receptor signaling pathway

hsa04621

NOD-like receptor signaling pathway

hsa04625

C-type lectin receptor signaling pathway

hsa04657

IL-17 signaling pathway

hsa04658

Th1 and Th2 cell differentiation

hsa04659

Th17 cell differentiation

hsa04660

T cell receptor signaling pathway

hsa04662

B cell receptor signaling pathway

hsa04668

TNF signaling pathway

hsa04722

Neurotrophin signaling pathway

hsa04912

GnRH signaling pathway

hsa04915

Estrogen signaling pathway

hsa04921

Oxytocin signaling pathway

hsa04926

Relaxin signaling pathway

hsa04932

Non-alcoholic fatty liver disease (NAFLD)

hsa04933

AGE-RAGE signaling pathway in diabetic complications

hsa05030

Cocaine addiction

hsa05031

Amphetamine addiction

hsa05120

Epithelial cell signaling in Helicobacter pylori infection

hsa05132

Salmonella infection

hsa05133

Pertussis

hsa05135

Yersinia infection

hsa05140

Leishmaniasis

hsa05142

Chagas disease (American trypanosomiasis)

hsa05161

Hepatitis B

hsa05162

Measles

hsa05166

Human T-cell leukemia virus 1 infection

hsa05167

Kaposi sarcoma-associated herpesvirus infection

hsa05169

Epstein-Barr virus infection

hsa05170

Human immunodeficiency virus 1 infection

hsa05200

Pathways in cancer

hsa05203

Viral carcinogenesis

hsa05210

Colorectal cancer

hsa05211

Renal cell carcinoma

hsa05224

Breast cancer

hsa05231

Choline metabolism in cancer

hsa05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

hsa05321

Inflammatory bowel disease (IBD)

hsa05323

Rheumatoid arthritis

hsa05418

Fluid shear stress and atherosclerosis

Network

Element

N00157

KSHV vGPCR to GNB/G-ERK signaling pathway

N00188

IL1-IL1R-JNK signaling pathway

N00189

KSHV K15 to JNK signaling pathway

N00438

TLR2/4-MAPK signaling pathway

N00439

HIV Nef to TLR2/4-MAPK signaling pathway

N00446

TNF-JNK signaling pathway

N00447

HIV Vpr/Tat to TNF-JNK signaling pathway

N00503

HTLV-1 Tax to TNF-JNK signaling pathway

N00543

HBV HBx to JNK signaling pathway

N00545

HBV HBx to ERK signaling pathway

N00547

HBV LHBs to PKC-ERK signaling pathway

N00551

HBV HBs to TLR2/4-MAPK signaling pathway

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3725 (JUN)
   04012 ErbB signaling pathway
    3725 (JUN)
   04310 Wnt signaling pathway
    3725 (JUN)
   04668 TNF signaling pathway
    3725 (JUN)
   04024 cAMP signaling pathway
    3725 (JUN)
09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    3725 (JUN)
  09143 Cell growth and death
   04210 Apoptosis
    3725 (JUN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    3725 (JUN)
   04530 Tight junction
    3725 (JUN)
09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    3725 (JUN)
   04621 NOD-like receptor signaling pathway
    3725 (JUN)
   04625 C-type lectin receptor signaling pathway
    3725 (JUN)
   04660 T cell receptor signaling pathway
    3725 (JUN)
   04658 Th1 and Th2 cell differentiation
    3725 (JUN)
   04659 Th17 cell differentiation
    3725 (JUN)
   04657 IL-17 signaling pathway
    3725 (JUN)
   04662 B cell receptor signaling pathway
    3725 (JUN)
  09152 Endocrine system
   04912 GnRH signaling pathway
    3725 (JUN)
   04915 Estrogen signaling pathway
    3725 (JUN)
   04921 Oxytocin signaling pathway
    3725 (JUN)
   04926 Relaxin signaling pathway
    3725 (JUN)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    3725 (JUN)
  09158 Development
   04380 Osteoclast differentiation
    3725 (JUN)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    3725 (JUN)
   05203 Viral carcinogenesis
    3725 (JUN)
   05231 Choline metabolism in cancer
    3725 (JUN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    3725 (JUN)
  09162 Cancer: specific types
   05210 Colorectal cancer
    3725 (JUN)
   05211 Renal cell carcinoma
    3725 (JUN)
   05224 Breast cancer
    3725 (JUN)
  09163 Immune disease
   05323 Rheumatoid arthritis
    3725 (JUN)
   05321 Inflammatory bowel disease (IBD)
    3725 (JUN)
  09165 Substance dependence
   05030 Cocaine addiction
    3725 (JUN)
   05031 Amphetamine addiction
    3725 (JUN)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    3725 (JUN)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease (NAFLD)
    3725 (JUN)
   04933 AGE-RAGE signaling pathway in diabetic complications
    3725 (JUN)
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    3725 (JUN)
   05132 Salmonella infection
    3725 (JUN)
   05135 Yersinia infection
    3725 (JUN)
   05133 Pertussis
    3725 (JUN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    3725 (JUN)
   05170 Human immunodeficiency virus 1 infection
    3725 (JUN)
   05162 Measles
    3725 (JUN)
   05161 Hepatitis B
    3725 (JUN)
   05167 Kaposi sarcoma-associated herpesvirus infection
    3725 (JUN)
   05169 Epstein-Barr virus infection
    3725 (JUN)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    3725 (JUN)
   05142 Chagas disease (American trypanosomiasis)
    3725 (JUN)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    3725 (JUN)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3725 (JUN)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    3725 (JUN)

SSDB

Motif

Pfam:

Jun bZIP_1 bZIP_2 bZIP_Maf ZapB PspA_IM30 Fib_alpha Jnk-SapK_ap_N FlaC_arch NBP1 TSC22 DUF3450 TFIIA

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P05412(Tchem)

UniProt:

P05412

LinkDB

Structure

PDB:

5T01 5FV8 1JNM 1A02 1T2K 1FOS 1S9K 1JUN

Position

1p32.1

AA seq 331 aa
MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDL
LTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAE
LHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGA
LSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETP
PLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANM
LREQVAQLKQKVMNHVNSGCQLMLTQQLQTF

NT seq 996 nt +upstreamnt +downstreamnt
atgactgcaaagatggaaacgaccttctatgacgatgccctcaacgcctcgttcctcccg
tccgagagcggaccttatggctacagtaaccccaagatcctgaaacagagcatgaccctg
aacctggccgacccagtggggagcctgaagccgcacctccgcgccaagaactcggacctc
ctcacctcgcccgacgtggggctgctcaagctggcgtcgcccgagctggagcgcctgata
atccagtccagcaacgggcacatcaccaccacgccgacccccacccagttcctgtgcccc
aagaacgtgacagatgagcaggagggcttcgccgagggcttcgtgcgcgccctggccgaa
ctgcacagccagaacacgctgcccagcgtcacgtcggcggcgcagccggtcaacggggca
ggcatggtggctcccgcggtagcctcggtggcagggggcagcggcagcggcggcttcagc
gccagcctgcacagcgagccgccggtctacgcaaacctcagcaacttcaacccaggcgcg
ctgagcagcggcggcggggcgccctcctacggcgcggccggcctggcctttcccgcgcaa
ccccagcagcagcagcagccgccgcaccacctgccccagcagatgcccgtgcagcacccg
cggctgcaggccctgaaggaggagcctcagacagtgcccgagatgcccggcgagacaccg
cccctgtcccccatcgacatggagtcccaggagcggatcaaggcggagaggaagcgcatg
aggaaccgcatcgctgcctccaagtgccgaaaaaggaagctggagagaatcgcccggctg
gaggaaaaagtgaaaaccttgaaagctcagaactcggagctggcgtccacggccaacatg
ctcagggaacaggtggcacagcttaaacagaaagtcatgaaccacgttaacagtgggtgc
caactcatgctaacgcagcagttgcaaacattttga

Homo sapiens (human): 3726

Entry

3726 CDS T01001

Gene name

JUNB, AP-1

Definition

(RefSeq) JunB proto-oncogene, AP-1 transcription factor subunit

K09028

transcription factor jun-B

Organism

hsa Homo sapiens (human)

Pathway

hsa04380

Osteoclast differentiation

hsa04668

TNF signaling pathway

Disease

H01463

Mycosis fungoides

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    3726 (JUNB)
09150 Organismal Systems
  09158 Development
   04380 Osteoclast differentiation
    3726 (JUNB)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3726 (JUNB)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    3726 (JUNB)

SSDB

Motif

Pfam:

Jun bZIP_1 bZIP_2 bZIP_Maf Jnk-SapK_ap_N ZapB PspA_IM30 MAD DUF737

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P17275(Tbio)

UniProt:

P17275 Q5U079

LinkDB

Position

19p13.13

AA seq 347 aa
MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGP
EGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGG
AGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPP
VYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFK
EEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKV
KTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF

NT seq 1044 nt +upstreamnt +downstreamnt
atgtgcactaaaatggaacagcccttctaccacgacgactcatacacagctacgggatac
ggccgggcccctggtggcctctctctacacgactacaaactcctgaaaccgagcctggcg
gtcaacctggccgacccctaccggagtctcaaagcgcctggggctcgcggacccggccca
gagggcggcggtggcggcagctacttttctggtcagggctcggacaccggcgcgtctctc
aagctcgcctcttcggagctggaacgcctgattgtccccaacagcaacggcgtgatcacg
acgacgcctacacccccgggacagtacttttacccccgcgggggtggcagcggtggaggt
gcagggggcgcagggggcggcgtcaccgaggagcaggagggcttcgccgacggctttgtc
aaagccctggacgatctgcacaagatgaaccacgtgacaccccccaacgtgtccctgggc
gctaccggggggcccccggctgggcccgggggcgtctacgccggcccggagccacctccc
gtttacaccaacctcagcagctactccccagcctctgcgtcctcgggaggcgccggggct
gccgtcgggaccgggagctcgtacccgacgaccaccatcagctacctcccacacgcgccg
cccttcgccggtggccacccggcgcagctgggcttgggccgcggcgcctccaccttcaag
gaggaaccgcagaccgtgccggaggcgcgcagccgggacgccacgccgccggtgtccccc
atcaacatggaagaccaagagcgcatcaaagtggagcgcaagcggctgcggaaccggctg
gcggccaccaagtgccggaagcggaagctggagcgcatcgcgcgcctggaggacaaggtg
aagacgctcaaggccgagaacgcggggctgtcgagtaccgccggcctcctccgggagcag
gtggcccagctcaaacagaaggtcatgacccacgtcagcaacggctgtcagctgctgctt
ggggtcaagggacacgccttctga

Homo sapiens (human): 3727

Entry

3727 CDS T01001

Gene name

JUND, AP-1

Definition

(RefSeq) JunD proto-oncogene, AP-1 transcription factor subunit

K04449

transcription factor jun-D

Organism

hsa Homo sapiens (human)

Pathway

hsa04010

MAPK signaling pathway

hsa04380

Osteoclast differentiation

hsa04657

IL-17 signaling pathway

hsa04928

Parathyroid hormone synthesis, secretion and action

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    3727 (JUND)
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    3727 (JUND)
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    3727 (JUND)
  09158 Development
   04380 Osteoclast differentiation
    3727 (JUND)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    3727 (JUND)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Jun
    3727 (JUND)

SSDB

Motif

Pfam:

Jun bZIP_1 bZIP_Maf bZIP_2 ZapB TSC22 Jnk-SapK_ap_N DUF3450 FlaC_arch Fib_alpha TEX13

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P17535(Tbio)

UniProt:

P17535

LinkDB

Structure

PDB:

5VPE 5VPC 5VPB 5VPF 5VPD 5VPA

Position

19p13.11

AA seq 347 aa
METPFYGDEALSGLGGGASGSGGSFASPGRLFPGAPPTAAAGSMMKKDALTLSLSEQVAA
ALKPAAAPPPTPLRADGAPSAAPPDGLLASPDLGLLKLASPELERLIIQSNGLVTTTPTS
SQFLYPKVAASEEQEFAEGFVKALEDLHKQNQLGAGAAAAAAAAAAGGPSGTATGSAPPG
ELAPAAAAPEAPVYANLSSYAGGAGGAGGAATVAFAAEPVPFPPPPPPGALGPPRLAALK
DEPQTVPDVPSFGESPPLSPIDMDTQERIKAERKRLRNRIAASKCRKRKLERISRLEEKV
KTLKSQNTELASTASLLREQVAQLKQKVLSHVNSGCQLLPQHQVPAY

NT seq 1044 nt +upstreamnt +downstreamnt
atggaaacacccttctacggcgatgaggcgctgagcggcctgggcggcggcgccagtggc
agcggcggcagcttcgcgtccccgggccgcttgttccccggggcgcccccgacggccgcg
gccggcagcatgatgaagaaggacgcgctgacgctgagcctgagtgagcaggtggcggca
gcgctcaagcctgcggccgcgccgcctcctacccccctgcgcgccgacggcgcccccagc
gcggcaccccccgacggcctgctcgcctctcccgacctggggctgctgaagctggcctcc
cccgagctcgagcgcctcatcatccagtccaacgggctggtcaccaccacgccgacgagc
tcacagttcctctaccccaaggtggcggccagcgaggagcaggagttcgccgagggcttc
gtcaaggccctggaggatttacacaagcagaaccagctcggcgcgggcgcggccgctgcc
gccgccgccgccgccgccggggggccctcgggcacggccacgggctccgcgccccccggc
gagctggccccggcggcggccgcgcccgaagcgcctgtctacgcgaacctgagcagctac
gcgggcggcgccgggggcgcggggggcgccgcgacggtcgccttcgctgccgaacctgtg
cccttcccgccgccgccacccccaggcgcgttggggccgccgcgcctggctgcgctcaag
gacgagccacagacggtgcccgacgtgccgagcttcggcgagagcccgccgttgtcgccc
atcgacatggacacgcaggagcgcatcaaggcggagcgcaagcggctgcgcaaccgcatc
gccgcctccaagtgccgcaagcgcaagctggagcgcatctcgcgcctggaagagaaagtg
aagaccctcaagagtcagaacacggagctggcgtccacggcgagcctgctgcgcgagcag
gtggcgcagctcaagcagaaagtcctcagccacgtcaacagcggctgccagctgctgccc
cagcaccaggtgcccgcgtactga

Homo sapiens (human): 8061

Entry

8061 CDS T01001

Gene name

FOSL1, FRA, FRA1, fra-1

Definition

(RefSeq) FOS like 1, AP-1 transcription factor subunit

K04502

fos-like antigen 1

Organism

hsa Homo sapiens (human)

Pathway

hsa04310

Wnt signaling pathway

hsa04380

Osteoclast differentiation

hsa04657

IL-17 signaling pathway

hsa05166

Human T-cell leukemia virus 1 infection

Network

nt06160 Human T-cell leukemia virus 1 (HTLV-1)

Element

N00509

HTLV-1 Tax to SRF-mediated transcription

Brite

KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    8061 (FOSL1)
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    8061 (FOSL1)
  09158 Development
   04380 Osteoclast differentiation
    8061 (FOSL1)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    8061 (FOSL1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:hsa03000]
    8061 (FOSL1)
Transcription factors [BR:hsa03000]
Eukaryotic Type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, Fos
    8061 (FOSL1)

SSDB

Motif

Pfam:

bZIP_1 bZIP_2 bZIP_Maf DUF3450 Siah-Interact_N HALZ Macoilin DUF4407 UPF0242

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P15407(Tbio)

UniProt:

P15407 A0A0S2Z595

LinkDB

Position

11q13.1

AA seq 271 aa
MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLG
PSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAA
KCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKE
GDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPST
PEPCASAHRKSSSSSGDPSSDPLGSPTLLAL

NT seq 816 nt +upstreamnt +downstreamnt
atgttccgagacttcggggaacccggcccgagctccgggaacggcggcgggtacggcggc
cccgcgcagcccccggccgcagcgcaggcagcccagcagaagttccacctggtgccaagc
atcaacaccatgagtggcagtcaggagctgcagtggatggtacagcctcatttcctgggg
cccagcagttaccccaggcctctgacctaccctcagtacagccccccacaaccccggcca
ggagtcatccgggccctggggccgcctccaggggtacgtcgaaggccttgtgaacagatc
agcccggaggaagaggagcgccgccgagtaaggcgcgagcggaacaagctggctgcggcc
aagtgcaggaaccggaggaaggaactgaccgacttcctgcaggcggagactgacaaactg
gaagatgagaaatctgggctgcagcgagagattgaggagctgcagaagcagaaggagcgc
ctagagctggtgctggaagcccaccgacccatctgcaaaatcccggaaggagccaaggag
ggggacacaggcagtaccagtggcaccagcagcccaccagccccctgccgccctgtacct
tgtatctccctttccccagggcctgtgcttgaacctgaggcactgcacacccccacactc
atgaccacaccctccctaactcctttcacccccagcctggtcttcacctaccccagcact
cctgagccttgtgcctcagctcatcgcaagagtagcagcagcagcggagacccatcctct
gacccccttggctctccaaccctcctcgctttgtga

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