KEGG ORTHOLOGY: K05101

ORTHOLOGY: K05101

Entry

K05101                      KO

Symbol

NTRK3, TRKC

Name

neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]

Pathway

map04020

Calcium signaling pathway

map04517

IgSF CAM signaling

map04722

Neurotrophin signaling pathway

map05230

Central carbon metabolism in cancer

Disease

H00043

Neuroblastoma

H01508

Salivary gland cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3
Protein kinases [BR:ko01001]
Receptor tyrosine kinases (RTK)
  TRK family [OT]
   K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3

Genes

HSA:	4916(NTRK3)

PTR:	467751(NTRK3)

PPS:	100994282(NTRK3)

GGO:	101140115(NTRK3)

PON:	100458353(NTRK3)

PPYG:

129013975(NTRK3)

NLE:	100585046(NTRK3)

HMH:	116482214(NTRK3)

SSYN:

129482107(NTRK3)

MCC:	697615(NTRK3)

MCF:	102122449(NTRK3)

MTHB:

126958903

MNI:	105488353(NTRK3)

CSAB:

103231127(NTRK3)

CATY:

105592428(NTRK3)

PANU:

101013710(NTRK3)

TGE:	112629228(NTRK3)

MLEU:

105544047(NTRK3)

RRO:	104661599(NTRK3)

RBB:	108535790(NTRK3)

TFN:	117070256(NTRK3)

PTEH:

111522905(NTRK3)

CANG:

105516228(NTRK3)

CJC:	100413191(NTRK3)

SBQ:	101048153(NTRK3)

CIMI:

108287614(NTRK3)

ANAN:

105707647(NTRK3)

CSYR:

103254803(NTRK3)

MMUR:

105884701(NTRK3)

LCAT:

123645162(NTRK3)

ERUF:

138381480(NTRK3)

PCOQ:

105809834(NTRK3)

OGA:	100951544(NTRK3)

MMU:	18213(Ntrk3)

MCAL:

110297619(Ntrk3)

MPAH:

110323509(Ntrk3)

RNO:	29613(Ntrk3)

MCOC:

116102418(Ntrk3)

ANU:	117723170(Ntrk3)

ASYL:

127667441(Ntrk3)

MUN:	110552446(Ntrk3)

CGE:	100755800(Ntrk3)

MAUA:

101843505(Ntrk3)

PROB:

127238144(Ntrk3)

PLEU:

114699869(Ntrk3)

PMAV:

102925829(Ntrk3)

MORG:

121451180(Ntrk3)

MFOT:

126508680

AAMP:

119802626(Ntrk3)

NGI:	103749925(Ntrk3)

HGL:	101723255(Ntrk3)

CPOC:

100731493(Ntrk3)

CCAN:

109678568(Ntrk3)

DORD:

105982398(Ntrk3)

DSP:	122123968(Ntrk3)

DMER:

138842061(Ntrk3)

PLOP:

125338575(Ntrk3)

NCAR:

124975939

MMMA:

107148345(Ntrk3)

ITI:	101965694(Ntrk3)

OCU:

103346142

OPI:	101523461(NTRK3)

OCZ:	121148990(NTRK3)

TUP:	102495274(NTRK3)

GVR:	103585719(NTRK3)

CFA:	100856261(NTRK3)

CLUD:

112653088(NTRK3)

VVP:	112921879(NTRK3)

VLG:	121489161(NTRK3)

NPO:	129510495(NTRK3)

AML:	100472259(NTRK3)

UMR:	103660166(NTRK3)

UAH:	113263672(NTRK3)

UAR:	123802425(NTRK3)

ELK:

111152589

LLV:

125104730

MPUF:

101676243(NTRK3)

MNP:	131999064(NTRK3)

MLK:	131835632(NTRK3)

NVS:

122893040

ORO:	101382416(NTRK3)

EJU:	114223284(NTRK3)

ZCA:	113909410(NTRK3)

MLX:	118023033(NTRK3)

NSU:	110572282(NTRK3)

LWW:	102738387(NTRK3)

FCA:	101085548(NTRK3)

PYU:	121042420(NTRK3)

PCOO:

112855467(NTRK3)

PBG:	122468252(NTRK3)

PVIV:

125168462(NTRK3)

LRUF:

124517372

LGF:	123582492(NTRK3)

AJU:

106965856

PTG:	102965762(NTRK3)

PPAD:

109273406(NTRK3)

PUC:

125910280

PLEZ:

122221632(NTRK3)

HHV:	120220033(NTRK3)

BTA:	539126(NTRK3)

BOM:	102266155(NTRK3)

BIU:

109575138

BBUB:

102401892(NTRK3)

BBIS:

104982764(NTRK3)

CHX:	102185689(NTRK3)

OAS:	101121631(NTRK3)

BTAX:

128066365(NTRK3)

CSUM:

138094833(NTRK3)

ODA:	120875661(NTRK3)

CCAD:

122455321(NTRK3)

MREE:

136146924(NTRK3)

MBEZ:

129550256(NTRK3)

SSC:	397511(NTRK3)

CFR:	102504225(NTRK3)

CBAI:

105075180(NTRK3)

CDK:	105085458(NTRK3)

VPC:	102530056(NTRK3)

BACU:

103011612(NTRK3)

BMUS:

118890764(NTRK3)

LVE:	103073064(NTRK3)

OOR:	101290435(NTRK3)

LALB:

132524324(NTRK3)

GMF:	115864701(NTRK3)

DDP:

132420748

DLE:	111169328(NTRK3)

PCAD:

102992259(NTRK3)

PSIU:

116749443(NTRK3)

PPHC:

136118710(NTRK3)

NASI:

112391560(NTRK3)

ECB:	100069852(NTRK3)

EPZ:	103555692(NTRK3)

EAI:	106832014(NTRK3)

MYB:	102248845(NTRK3)

MYD:	102761142(NTRK3)

MMYO:

118679277(NTRK3)

MLF:	102433411(NTRK3) 102443290

MDT:	132222852(NTRK3)

MYUM:

138998358(NTRK3)

PKL:	118704336(NTRK3)

EFUS:

103301940(NTRK3)

MNA:	107527826(NTRK3)

DRO:	112305916(NTRK3)

SHON:

118991988(NTRK3)

AJM:	119049115(NTRK3)

PDIC:

114488572(NTRK3)

PHAS:

123809782(NTRK3)

MMF:	118640961(NTRK3)

PPAM:

129073895(NTRK3)

HAI:	109394772(NTRK3)

RFQ:	117018962(NTRK3)

PALE:

102879798(NTRK3)

PGIG:

120599263(NTRK3)

PVP:

105306725

RAY:	107514177(NTRK3)

MJV:	108402158(NTRK3)

TOD:	119244304(NTRK3)

SARA:

101544461(NTRK3)

SFUM:

130023344(NTRK3)

SETR:

126022364(NTRK3)

LAV:	100676434(NTRK3)

TMU:

101346626

ETF:

101663738

DNM:	101435243(NTRK3)

MDO:	100013667(NTRK3)

GAS:	123238091(NTRK3)

SHR:	100926082(NTRK3)

AFZ:

127551373

PCW:	110193073(NTRK3)

TVP:

118829619

PBRV:

138169252(NTRK3)

MLAO:

141521506(NTRK3)

OAA:	100078146(NTRK3)

TACU:

119928383(NTRK3)

GGA:	396081(NTRK3)

PCOC:

116225399(NTRK3)

MGP:	100546817(NTRK3)

CJO:	107318811(NTRK3)

TPAI:

128075412(NTRK3)

LMUT:

125698223(NTRK3)

NMEL:

110403788(NTRK3)

APLA:

101790659(NTRK3)

AACU:

137862899(NTRK3)

ACYG:

106036476(NTRK3)

CATA:

118251966(NTRK3)

AFUL:

116493605(NTRK3)

TGU:	100227403(NTRK3)

LSR:	110470597(NTRK3)

SCAN:

103816080(NTRK3)

PMOA:

120509033(NTRK3)

OTC:	121343616(NTRK3)

PRUF:

121354547(NTRK3)

ATRC:

139596780(NTRK3)

GFR:	102035445(NTRK3)

FAB:	101806756(NTRK3)

OMA:	130257407(NTRK3)

PHI:	102100349(NTRK3)

PMAJ:

107209364(NTRK3)

CCAE:

111933874(NTRK3)

CCW:	104683930(NTRK3)

CBRC:

103621307(NTRK3)

ACOE:

138116518(NTRK3)

ETL:	114058028(NTRK3)

ZAB:	102066773(NTRK3)

ZLE:	135452090(NTRK3)

ACHL:

103799487(NTRK3)

SVG:	106859227(NTRK3)

MMEA:

130573394(NTRK3)

HRT:	120758597(NTRK3)

SATI:

136366972(NTRK3)

CFAI:

136297079(NTRK3)

CCIC:

134049058(NTRK3)

FPG:	101912123(NTRK3)

FCH:	102058367(NTRK3)

NNT:	104411376(NTRK3)

SHAB:

115612869(NTRK3)

ACUN:

113484125(NTRK3)

SURA:

141948259(NTRK3)

TALA:

104362611(NTRK3)

ACHC:

115341522(NTRK3)

HLE:	104834564(NTRK3)

AGEN:

126043896

HHAR:

128150999(NTRK3)

BBUT:

142038997(NTRK3)

GCL:

127020519

DPUB:

104303303(NTRK3)

PPUS:

135183173(NTRK3)

EGZ:	104122884(NTRK3)

NNI:	104017079(NTRK3)

PADL:

103926320(NTRK3)

AFOR:

103896679(NTRK3)

CBOR:

142086638(NTRK3)

CBOY:

140655486(NTRK3)

MAME:

142411781(NTRK3)

CLV:	102090767(NTRK3)

CNIC:

135992355(NTRK3)

MUI:

104542849

PGUU:

104469189

PLET:

104624337(NTRK3)

EHS:	104510229(NTRK3)

CMAC:

104478465(NTRK3)

CUCA:

104059700(NTRK3)

TEO:	104382242(NTRK3)

GAME:

129210799(NTRK3)

OHA:	104332078(NTRK3)

CPEA:

104391954(NTRK3)

CVF:	104288398(NTRK3)

RTD:	128915077(NTRK3)

CRID:

134520742(NTRK3)

LMIC:

141748911(NTRK3)

AAM:	106497638(NTRK3)

AROW:

112970083(NTRK3)

NPD:	112944789(NTRK3)

TGT:	104567316(NTRK3)

DNE:	112996016(NTRK3)

SCAM:

104148193(NTRK3)

ASN:	102382323(NTRK3)

AMJ:	102576983(NTRK3)

CPOO:

109309128(NTRK3)

GGN:	109288501(NTRK3)

PSS:	102460804(NTRK3)

CIZ:	142019433(NTRK3)

CMY:	102939573(NTRK3)

CCAY:

125643361(NTRK3)

LKP:	140895046(NTRK3)

NDS:	141995347(NTRK3)

DCC:	119862802(NTRK3)

CPIC:

101936539(NTRK3)

TST:	117883981(NTRK3)

CABI:

116840111(NTRK3)

MRV:	120373237(NTRK3)

ACS:	100565655(ntrk3)

ASAO:

132762301(NTRK3)

PVT:	110072967(NTRK3)

SUND:

121935244(NTRK3)

PBI:	103063255(NTRK3)

PMUR:

107288613(NTRK3)

CTIG:

120315086(NTRK3)

TSR:

106554229

PGUT:

117669865(NTRK3)

PCAE:

139324174(NTRK3)

APRI:

131184685(NTRK3)

PTEX:

113442041(NTRK3)

NSS:	113421471(NTRK3)

VKO:	123027746(NTRK3)

PMUA:

114584210(NTRK3)

PRAF:

128401335(NTRK3)

ZVI:	118093072(NTRK3)

HCG:	128334970(NTRK3)

GJA:	107111007(NTRK3)

EMC:	129345611(NTRK3)

XLA:	108711464 108712840

XTR:	100487541(ntrk3)

NPR:	108786949(NTRK3)

RTEM:

120931183(NTRK3)

ACAT:

141131301(NTRK3)

PADS:

140324646(NTRK3)

BBUF:

120985951(NTRK3)

BGAR:

122927536(NTRK3)

DTC:	141084202(NTRK3)

PWL:	138284208(NTRK3)

MUO:	115459889(NTRK3)

GSH:	117348360(NTRK3)

DRE:	568668(ntrk3a) 798577(ntrk3b)

SRX:	107706933 107707526 107714007 107733954

SANH:

107654144 107662328 107674750 107701581

SGH:	107573919 107581857 107583141 107594754

CCAR:

109070444 109078561(ntrk3b) 109079954 109110590

CAUA:

113042814 113051985 113074629 113080856 113083372 113095406 113105565

CGIB:

127947250 127962695 128014143 128017335

PTET:

122330976(ntrk3a) 122347982(ntrk3b)

LROH:

127156264(ntrk3a) 127168417(ntrk3b)

OMC:	131544069(ntrk3b)

PPRM:

120460245(ntrk3a) 120469785(ntrk3b)

RKG:	130085188(ntrk3a) 130091346(ntrk3b)

MAMB:

125246759(ntrk3a) 125264441(ntrk3b)

CIDE:

127507419 127516399

CERY:

137014996(ntrk3a) 137030170(ntrk3b)

MASI:

127413494 127435924 127437831 127444804

TROS:

130551558(ntrk3a) 130558094(ntrk3b)

TDW:	130414387(ntrk3a) 130420597(ntrk3b)

MANU:

129429065(ntrk3b) 129433906(ntrk3a)

PDAB:

135781227(ntrk3a) 135783481(ntrk3b)

IPU:	108269325(ntrk3a) 108270548(ntrk3b)

IFU:	128611022(ntrk3a) 128613375

PHYP:

113536380(ntrk3) 113546626

SMEO:

124386184(ntrk3a) 124391689(ntrk3b)

TFD:	113648204(ntrk3a) 113653158(ntrk3b)

TVC:	132855571(ntrk3b) 132855815(ntrk3a)

CGAR:

128532366(ntrk3a) 128542547(ntrk3b)

NGRA:

132891038(ntrk3a) 132899296(ntrk3b)

TRN:	134319639(ntrk3a) 134331118(ntrk3b)

AMEX:

103031048(ntrk3a) 103046759(ntrk3b)

CMAO:

118806539(ntrk3a) 118819378(ntrk3b)

EEE:	113573962(ntrk3) 113584773

CHAR:

105892129(ntrk3a) 105893046(ntrk3b)

SPIL:

134069473(ntrk3b) 134093450(ntrk3a)

ASAD:

121694234(ntrk3b) 121724464(ntrk3a)

TRU:	101073836(ntrk3)

TFS:	130515811(ntrk3b)

TNG:	GSTEN00022390G001 GSTEN00022402G001

LCO:	104921516 104939181

TBEN:

117491245(ntrk3a) 117496970(ntrk3b)

CGOB:

115006298(ntrk3) 115009608

PGEO:

117442880 117448449(ntrk3a)

GACU:

117532804(ntrk3a)

EMAC:

134862547(ntrk3b) 134882038(ntrk3a)

ELY:	117251295 117256475(ntrk3b)

EFO:	125904595(ntrk3b)

PLEP:

121941244(ntrk3b) 121950400(ntrk3a)

SLUC:

116040213(ntrk3a) 116057163(ntrk3b)

ECRA:

117945786(ntrk3b) 117949207(ntrk3a)

ESP:	116694048 116694555

PFLV:

114559601 114560571

GAT:	120809241 120835421

PPUG:

119195809(ntrk3a) 119226314(ntrk3b)

AFB:	129103908(ntrk3b) 129108280

CLUM:

117726317(ntrk3b) 117732328

PSWI:

130192923(ntrk3b) 130195768

CANA:

137785478(ntrk3b) 137803850

CVE:	137880902 137887461

MSAM:

119890754(ntrk3b)

SCHU:

122875077(ntrk3a) 122878183(ntrk3b)

CUD:	121510525(ntrk3b) 121515324

SPUL:

138585357(ntrk3b) 138613370

LMIX:

132967154 132979542(ntrk3b)

HTC:	141787625(ntrk3b) 141796446

ALAT:

119018748(ntrk3b) 119024832

ASTR:

137593392(ntrk3a) 137594827(ntrk3b)

MZE:	101471509(ntrk3) 101471879

ONL:	100698004(ntrk3) 100703725

OAU:	116319269 116325590(ntrk3b)

OLA:	101161874(ntrk3) 101168685

OML:	112151688 112160700(ntrk3b)

CSAI:

133444479 133456756 133456763

XMA:	102221231(ntrk3) 102229432

XCO:	114143172(ntrk3) 114151530

XHE:	116718351(ntrk3) 116729603

PRET:

103462183(ntrk3) 103465767

PFOR:

103130161 103136001(ntrk3)

PLAI:

106941425(ntrk3) 106955642

PMEI:

106910523(ntrk3) 106930680

GAF:	122825271(ntrk3b) 122835215

PPRL:

129366167 129369507(ntrk3b)

CVG:	107087974(ntrk3) 107101595

CTUL:

119776449 119788513(ntrk3b)

GMU:	124867174(ntrk3b) 124878078

NFU:	107381974(ntrk3) 107396553

KMR:	108241607(ntrk3b) 108249944

ALIM:

106522525(ntrk3) 106532941

NWH:	119426491(ntrk3b)

AOCE:

111571543(ntrk3a) 111587396(ntrk3b)

EJA:	138205768 138212867(ntrk3b)

BFRE:

138616190(ntrk3b) 138632786(ntrk3a)

MCEP:

125005775(ntrk3b) 125015523

CSEM:

103379301(ntrk3) 103379855

POV:	109624753 109640595

SSEN:

122761896 122776392

SSOE:

131459992(ntrk3b) 131470561(ntrk3a)

HHIP:

117753535(ntrk3b) 117762750

HSP:	118110237 118114223(ntrk3b)

PPLT:

128444185 128445687(ntrk3b)

SMAU:

118302491(ntrk3b) 118315736

LCF:	108884587(ntrk3a) 108897717(ntrk3b)

SDU:	111221530(ntrk3) 111234822

SLAL:

111647668 111672341(ntrk3)

XGL:	120793236(ntrk3a) 120795789(ntrk3b)

HCQ:	109513079 109513862(ntrk3)

SSCV:

125966674(ntrk3b) 125970576

SBIA:

133498200(ntrk3b)

PEE:	133398119(ntrk3b) 133402598

PTAO:

133474116(ntrk3b) 133477891(ntrk3a)

BPEC:

110169490 110175408(ntrk3)

ENY:	140349397 140381414(ntrk3b)

MALB:

109967270 109969925

BSPL:

114852458(ntrk3b) 114856775

SJO:	128355872(ntrk3b) 128359524

SSCO:

133981562 134001465(ntrk3b)

TTY:	137182450(ntrk3a) 137186770(ntrk3b)

GMH:	115550999 115559220(ntrk3)

SASA:

106560958 106573628 106588069

STRU:

115151838 115182693 115196928

OTW:	112219222(ntrk3a) 112252252

OMY:	110493835(ntrk3a) 110510575 110512363 110513060

OGO:	123999529 124020250 124035359 124038121(ntrk3a)

ONE:	115109280 115134397

OKI:	109867469 109884949 109889245 116359544

OKE:	118396561(ntrk3a) 118400862

OMM:	135509492(ntrk3a) 135524526 135552290 135554572

OCLA:

139381714 139384431 139384445 139386570

SALP:

111952403 111960971

SNH:	120053194 120066647(ntrk3a)

SFON:

129862628(ntrk3a) 129867202

CCLU:

121531766 121564390 121576745

ELS:	105008955 105018511(ntrk3)

OEP:	134028382(ntrk3b)

SFM:	108926537 108940786

PKI:	111845116 111845753

AANG:

118215714 118227992

AROT:

135241881 135255501

CCOG:

133111384 133130617

LOC:	102686120(ntrk3)

PSPA:

121294429 121299323

ARUT:

117427694 117962476

PSEX:

120541406

LCM:	102348900(NTRK3)

CMK:	103189906(ntrk3a)

RTP:	109931414(ntrk3a)

CPLA:

CPUN:

HOC:

SCAU:

LERI:

HAKA:

PMRN:

103091833(NTRK2)

LRJ:	133343825(NTRK2)

BFO:

BBEL:

AJC:

SKO:

PFLL:

CLEC:

PTRU:

HAZT:

DSV:

DALB:

CSCU:

CVS:

PMEO:

PVUL:

PCAN:

HRF:

HRJ:

HCRA:

DPOL:

MAEA:

LJP:

LAK:

Reference

PMID:8494647

Authors

Valenzuela DM, Maisonpierre PC, Glass DJ, Rojas E, Nunez L, Kong Y, Gies DR, Stitt TN, Ip NY, Yancopoulos GD

Title

Alternative forms of rat TrkC with different functional capabilities.

Journal

Neuron 10:963-74 (1993)
DOI:10.1016/0896-6273(93)90211-9

Sequence

[rno:29613]

Reference

PMID:19344762

Authors

Otnaess MK, Djurovic S, Rimol LM, Kulle B, Kahler AK, Jonsson EG, Agartz I, Sundet K, Hall H, Timm S, Hansen T, Callicott JH, Melle I, Werge T, Andreassen OA

Title

Evidence for a possible association of neurotrophin receptor (NTRK-3) gene polymorphisms with hippocampal function and schizophrenia.

Journal

Neurobiol Dis 34:518-24 (2009)
DOI:10.1016/j.nbd.2009.03.011

LinkDB

DBGET integrated database retrieval system