KEGG   ORTHOLOGY: K12805
Entry
K12805                      KO                                     
Symbol
NLRC4, CARD12
Name
NLR family CARD domain-containing protein 4
Pathway
map04621  NOD-like receptor signaling pathway
map05131  Shigellosis
map05132  Salmonella infection
map05134  Legionellosis
map05135  Yersinia infection
Disease
H01748  Autoinflammation with infantile enterocolitis
H02159  Familial cold autoinflammatory syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05131 Shigellosis
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05135 Yersinia infection
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
   05134 Legionellosis
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors
    K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
Pattern recognition receptors [BR:ko04054]
 Cytoplasmic pattern recognition receptors
  NOD-like receptors
   K12805  NLRC4, CARD12; NLR family CARD domain-containing protein 4
Genes
HSA: 58484(NLRC4)
PTR: 459135(NLRC4)
PPS: 100977377(NLRC4)
GGO: 101140214(NLRC4)
PON: 100449353(NLRC4)
NLE: 100595956(NLRC4)
MCC: 706378(NLRC4)
MCF: 102142882(NLRC4)
CSAB: 103220528(NLRC4)
CATY: 105578400(NLRC4)
PANU: 100998325(NLRC4)
TGE: 112604823(NLRC4)
RRO: 104681702(NLRC4)
RBB: 108528685(NLRC4)
TFN: 117062499(NLRC4)
PTEH: 111545415(NLRC4)
CSYR: 103274351(NLRC4)
OGA: 100941241(NLRC4)
MMU: 268973(Nlrc4)
MCAL: 110312299(Nlrc4)
MPAH: 110335928(Nlrc4)
RNO: 298784(Nlrc4)
MCOC: 116080207(Nlrc4)
MUN: 110565106(Nlrc4)
CGE: 100765631(Nlrc4)
PLEU: 114696038(Nlrc4)
NGI: 103746764(Nlrc4)
HGL: 101712438(Nlrc4)
CPOC: 100735110(Nlrc4)
CCAN: 109699038(Nlrc4)
DORD: 105983561(Nlrc4)
DSP: 122122551(Nlrc4)
NCAR: 124963308
TUP: 102469158(NLRC4)
CFA: 102153882
VLG: 121491874(NLRC4)
AML: 100464785(NLRC4)
MPUF: 101687986(NLRC4)
ORO: 101376440(NLRC4)
EJU: 114219603(NLRC4)
ZCA: 113938384(NLRC4)
MLX: 118007513(NLRC4)
FCA: 101087657(NLRC4)
PYU: 121044321(NLRC4)
PBG: 122497273(NLRC4)
PTG: 102958929(NLRC4)
PPAD: 109266166(NLRC4)
AJU: 106967889(NLRC4)
HHV: 120244018(NLRC4)
BTA: 512480(NLRC4)
BOM: 102269253(NLRC4)
BIU: 109565964(NLRC4)
BBUB: 102405176(NLRC4)
CHX: 102189315(NLRC4)
OAS: 101104138(NLRC4)
ODA: 120851647(NLRC4)
CCAD: 122441540(NLRC4)
SSC: 100515078(NLRC4)
CFR: 102524619(NLRC4)
CBAI: 105078949(NLRC4)
CDK: 105095602(NLRC4)
VPC: 102537334(NLRC4)
BACU: 102998755(NLRC4)
LVE: 103073097(NLRC4)
OOR: 101287377(NLRC4)
DLE: 111174903(NLRC4)
PCAD: 102980423(NLRC4)
PSIU: 116764186(NLRC4)
ECB: 100070605(NLRC4)
EPZ: 103567720(NLRC4)
EAI: 106839897(NLRC4)
MYB: 102240830(NLRC4)
MYD: 102755951(NLRC4)
MMYO: 118669122(NLRC4)
MLF: 102417417(NLRC4)
MNA: 107541770(NLRC4)
PKL: 118717129(NLRC4)
HAI: 109388792(NLRC4)
DRO: 112297814(NLRC4)
SHON: 119001289(NLRC4)
AJM: 119050344(NLRC4)
PDIC: 114498723(NLRC4)
PHAS: 123811505(NLRC4)
MMF: 118630664(NLRC4)
RFQ: 117032956(NLRC4)
PALE: 102886154(NLRC4)
PGIG: 120621795(NLRC4)
PVP: 105300072(NLRC4)
RAY: 107505750(NLRC4)
TOD: 119258666(NLRC4)
SARA: 101545252(NLRC4)
TMU: 101360631
DNM: 101446914(NLRC4)
CLV: 102089994(NLRC4)
EGZ: 104124110(NLRC4)
NNI: 104018706(NLRC4)
PADL: 103922882(NLRC4)
ACHC: 115350257(NLRC4)
ASN: 102380000(NLRC4)
AMJ: 102561955(NLRC4)
CPOO: 109319884(NLRC4)
GGN: 109304829(NLRC4)
ACS: 100561094(nlrc4)
SUND: 121919552(NLRC4)
PBI: 103057003(NLRC4)
PMUR: 107287479(NLRC4)
TSR: 106544562(NLRC4)
PGUT: 117671880(NLRC4)
VKO: 123035409(NLRC4)
GJA: 107122647(NLRC4)
XLA: 108716654(nlrc4.L)
XTR: 733844(nlrc4)
NPR: 108799665(NLRC4)
RTEM: 120937479(NLRC4)
BBUF: 120998780(NLRC4)
BGAR: 122936126(NLRC4)
LOC: 102696211(nlrc4)
PSPA: 121316731
ARUT: 117410620
LCM: 102362496(NLRC4)
RTP: 109939060(nlrc4)
APLC: 110976090
MYI: 110464041
PDAM: 113664313
 » show all
Reference
  Authors
Poyet JL, Srinivasula SM, Tnani M, Razmara M, Fernandes-Alnemri T, Alnemri ES
  Title
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1.
  Journal
J Biol Chem 276:28309-13 (2001)
DOI:10.1074/jbc.C100250200
  Sequence
[hsa:58484]
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