KEGG   ORTHOLOGY: K16980
Entry
K16980            RNA       KO                                     
Symbol
MIRLET7
Name
microRNA let-7
Pathway
map04361  Axon regeneration
map05206  MicroRNAs in cancer
map05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04361 Axon regeneration
    K16980  MIRLET7; microRNA let-7
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K16980  MIRLET7; microRNA let-7
   05207 Chemical carcinogenesis - receptor activation
    K16980  MIRLET7; microRNA let-7
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K16980  MIRLET7; microRNA let-7
  09184 RNA family
   03100 Non-coding RNAs
    K16980  MIRLET7; microRNA let-7
Exosome [BR:ko04147]
 Exosomal RNA
  Exosomal RNA of breast milk
   K16980  MIRLET7; microRNA let-7
  Exosomal RNA of saliva
   K16980  MIRLET7; microRNA let-7
  Exosomal RNA of ovarian cancer cells
   K16980  MIRLET7; microRNA let-7
  Exosomal RNA of renal carcinoma cells
   K16980  MIRLET7; microRNA let-7
  Exosomal RNA of other cancer cells
   K16980  MIRLET7; microRNA let-7
Non-coding RNAs [BR:ko03100]
 Other eukaryotic RNA
  Micro RNA
   K16980  MIRLET7; microRNA let-7
Genes
HSA: 406881(MIRLET7A1) 406882(MIRLET7A2) 406883(MIRLET7A3) 406884(MIRLET7B) 406885(MIRLET7C) 406886(MIRLET7D) 406887(MIRLET7E) 406888(MIRLET7F1) 406889(MIRLET7F2) 406890(MIRLET7G) 406891(MIRLET7I) 407054(MIR98)
PTR: 100316033(MIRLET7A-3) 100316034(MIRLET7C) 100316035(MIRLET7D) 100316036(MIRLET7E) 100316037(MIRLET7I) 100316306(MIRLET7B) 100316307(MIRLET7G) 100316361(MIRLET7A-1) 100316362(MIRLET7F-1) 100316420(MIRLET7A-2) 100316421(MIRLET7F-2) 751899(MIR98)
PPS: 102464138(MIR98) 114482488(MIRLET7I) 114482512(MIRLET7A-2) 114482525(MIRLET7C) 114482620(MIRLET7E) 114482633(MIRLET7B) 114482654(MIRLET7F) 114483539(MIRLET7G) 114483573(MIRLET7A-1)
GGO: 102464965(MIRLET7C) 102464966(MIRLET7B) 102464968(MIRLET7E) 102464970(MIRLET7I) 102465912(MIR98) 102465951(MIRLET7G) 102466122(MIRLET7F) 102466560(MIRLET7A)
MCC: 100315170(MIRLET7A-2) 100315171(MIRLET7C) 100315172(MIRLET7D) 100315173(MIRLET7F-1) 100315174(MIRLET7F-2) 100315382(MIR98) 100315389(MIRLET7B) 100315390(MIRLET7G) 100315442(MIRLET7A-3) 100315443(MIRLET7I) 100315501(MIRLET7A-1) 100315502(MIRLET7E)
MMU: 102465198(Mir7j) 102465309(Mir7k) 387244(Mirlet7a-1) 387245(Mirlet7b) 387246(Mirlet7c-1) 387247(Mirlet7d) 387248(Mirlet7e) 387249(Mirlet7g) 387251(Mirlet7i) 387252(Mirlet7f-1) 387253(Mirlet7f-2) 723947(Mir98) 723965(Mirlet7a-2) 723966(Mirlet7c-2)
RNO: 100313972(Mirlet7d) 100313989(Mirlet7a-2) 100313990(Mirlet7b) 100313991(Mirlet7e) 100313992(Mirlet7f2) 100313993(Mirlet7i) 100314018(Mir98) 100314184(Mirlet7c1) 100314213(Mirlet7a1) 100314224(Mirlet7c2) 100314277(Mirlet7f-1os) 100526574(Mirlet7f-1) 100526596(Mir3596b) 100526599(Mir3596c) 100526642(Mir3596a) 104796557(Mirlet7g)
CGE: 102464838(Mirlet7b) 102464839(Mirlet7c-1) 102464840(Mirlet7f) 102464841(Mirlet7g) 102465945(Mirlet7d) 102466520(Mirlet7a-1) 102466559(Mir98)
OCU: 114482225(MIR98) 114482267(MIRLET7A-1) 114482277(MIRLET7A-3) 114482286(MIRLET7C) 114482290(MIRLET7D) 114482301(MIRLET7F-2) 114482306(MIRLET7G) 114483266(MIRLET7I) 114483454(MIRLET7A-2) 114483462(MIRLET7F-1) 114483782(MIRLET7B)
TUP: 104795962(MIRLET7A) 104795984(MIRLET7G) 104795989(MIRLET7F) 104796044(MIRLET7I) 104796281(MIR98) 104796612(MIRLET7E)
CFA: 100885880(MIRLET7F) 100885980(MIRLET7B) 100886041(MIRLET7A-1) 100886083(MIRLET7C) 100886093(MIRLET7A-2) 100886114(MIRLET7E) 100886120(MIRLET7G) 104795022(MIRLET7D)
BTA: 100170919(MIRLET7C) 100170921(MIRLET7A-3) 100170922(MIRLET7B) 100170929(MIRLET7A-2) 100170931(MIRLET7E) 100498829(MIR3596) 790974(MIRLET7F-2) 791024(MIR98) 791025(MIRLET7D) 791050(MIRLET7G) 791056(MIRLET7A-1) 791061(MIRLET7F-1) 791064(MIRLET7I)
CHX: 104795700(MIRLET7A) 104795701(MIRLET7D) 104795702(MIRLET7E) 104795703(MIRLET7F) 104795704(MIRLET7G) 104795868(MIR98) 104796561(MIRLET7C) 104797232(MIRLET7B) 104797233(MIRLET7I)
OAS: 102464495(MIRLET7B) 102465804(MIRLET7A) 102465805(MIRLET7F) 102465806(MIRLET7G) 102465929(MIRLET7C) 102466243(MIRLET7D) 102466855(MIRLET7I)
SSC: 100170412(MIRLET7C) 100316600(MIRLET7I) 100316608(MIRLET7F-1) 100498702(MIRLET7A-1) 100498765(MIR98) 100498768(MIRLET7G) 100498799(MIRLET7E) 100628333(MIRLET7A-2) 104794424(MIRLET7D) 104797448(MIRLET7F-2)
ECB: 100314820(MIRLET7A) 100314867(MIRLET7G) 100314889(MIRLET7D) 100314974(MIRLET7E) 100315026(MIRLET7C) 100315027(MIRLET7A-2) 100315031(MIR98) 100315074(MIRLET7F)
EFUS: 104795455(MIRLET7D) 104795456(MIRLET7F) 104797138(MIRLET7C) 104797195(MIRLET7E)
MDO: 100034267(MIRLET7A-2) 100034268(MIRLET7G) 100034269(MIRLET7I) 100034286(MIRLET7A-3) 100034287(MIRLET7B) 100034296(MIRLET7A-1) 100034297(MIRLET7F-1) 100034298(MIRLET7D) 100315605(MIRLET7F-2)
SHR: 102464790(MIRLET7G) 102464809(MIRLET7I) 102466098(MIRLET7A)
OAA: 100314497(MIRLET7E) 100314560(MIR98) 100314561(MIRLET7F-2) 100314581(MIRLET7D) 100314596(MIRLET7F-1) 100314620(MIRLET7B) 100314720(MIRLET7G) 104794699(MIRLET7C-1)
GGA: 777834(MIRLET7G) 777836(MIRLET7D) 777837(MIRLET7F1) 777838(MIRLET7F2) 777863(MIRLET7A2) 777866(MIRLET7E) 777867(MIRLET7A1) 777922(MIRLET7I) 777925(MIRLET7A3) 777926(MIRLET7B) 777928(MIRLET7C)
TGU: 100886587(MIRLET7B) 100886597(MIRLET7E) 100886598(MIRLET7A-1) 100886599(MIRLET7A-2) 100886600(MIRLET7C-2) 100886607(MIRLET7G-1) 100886608(MIRLET7F) 100886612(MIRLET7D) 100886678(MIRLET7I) 100886681(MIRLET7A-4) 100886705(MIRLET7A-3)
ACS: 104794081(mirlet7a) 104794082(mirlet7b) 104794083(mirlet7c-1) 104794084(mirlet7e) 104794085(mirlet7f-1) 104794086(mirlet7f-2) 104794087(mirlet7g) 104794201(mir98) 104796310(mirlet7c-2) 104796697(mirlet7d) 104796698(mirlet7i)
XTR: 100886776(mirlet7b) 100886793(mir98) 100886828(mirlet7c) 100886829(mirlet7g) 100886830(mirlet7i) 100886840(mirlet7a) 100886893(mirlet7e-2) 100886911(mirlet7f) 100886913(mirlet7e-1)
DRE: 100033533(mirlet7a-1) 100033534(mirlet7a-2) 100033535(mirlet7a-3) 100033536(mirlet7a-4) 100033537(mirlet7a-5) 100033538(mirlet7a-6) 100033539 100033540(mirlet7c-1) 100033541(mirlet7c-2) 100033542(mirlet7d-1) 100033543(mirlet7d-2) 100033545(mirlet7f) 100033546(mirlet7g-1) 100033547(mirlet7g-2) 100033548 100033549 100033723(mirlet7j) 100628655
TRU: 102464213(mirlet7e) 102464222(mirlet7a-3) 102464236(mirlet7i) 102464242(mirlet7a-2) 102464244(mirlet7d) 102464251(mirlet7b) 102464287(mirlet7g) 102466018(mirlet7j) 102466310(mirlet7h) 102466329(mirlet7a-1)
OLA: 102464689(mirlet7a-1) 102464690(mirlet7b-1) 102464698(mirlet7e) 102464738(mirlet7a-4) 102464765(mirlet7b-2) 102466084(mirlet7g) 102466094(mirlet7a-3) 102466475(mirlet7a-2) 102466488(mirlet7c)
CIN: 100187670(mirlet7d) 100187674(mirlet7b) 100187688(mirlet7a-2) 100187699(mirlet7a-1)
SPU: 100314428(Mirlet7)
SKO: 100526441(Mirlet7)
DME: Dmel_CR42949(mir-let7)
DMO: Dmoj_GI24995(Dmoj_let-7)
AME: 100315656(Mirlet7)
NVI: 100526358(Mirlet7)
TCA: 100314377(Mirlet7)
BMOR: 102464293(Mirlet7)
API: 100630930(Mirlet7)
CEL: CELE_C05G5.6(let-7)
BMY: BM_BM13036(Bma-let-7)
 » show all
Reference
PMID:19221491
  Authors
Peter ME
  Title
Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression.
  Journal
Cell Cycle 8:843-52 (2009)
DOI:10.4161/cc.8.6.7907
  Sequence
[hsa:406881 406882 406883 406884 406886 406887 406888 406889 406890 406891]
Reference
PMID:11679670
  Authors
Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T
  Title
Identification of novel genes coding for small expressed RNAs.
  Journal
Science 294:853-8 (2001)
DOI:10.1126/science.1064921
  Sequence
[hsa:406881]
Reference
PMID:15766527
  Authors
Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ
  Title
RAS is regulated by the let-7 microRNA family.
  Journal
Cell 120:635-47 (2005)
DOI:10.1016/j.cell.2005.01.014
Reference
PMID:34198264
  Authors
Law YY, Lee WF, Hsu CJ, Lin YY, Tsai CH, Huang CC, Wu MH, Tang CH, Liu JF
  Title
miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts.
  Journal
Aging (Albany NY) 13:17227-17236 (2021)
DOI:10.18632/aging.203201
  Sequence
[hsa:406885]
Reference
PMID:23211491
  Authors
Siragam V, Rutnam ZJ, Yang W, Fang L, Luo L, Yang X, Li M, Deng Z, Qian J, Peng C, Yang BB
  Title
MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11.
  Journal
Oncotarget 3:1370-85 (2012)
DOI:10.18632/oncotarget.717
  Sequence
[hsa:407054]
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