KEGG   PATHWAY: aam00564
Entry
aam00564                    Pathway                                
Name
Glycerophospholipid metabolism - Apteryx mantelli mantelli (North Island brown kiwi)
Class
Metabolism; Lipid metabolism
Pathway map
aam00564  Glycerophospholipid metabolism
aam00564

Module
aam_M00090  Phosphatidylcholine (PC) biosynthesis, choline => PC [PATH:aam00564]
aam_M00091  Phosphatidylcholine (PC) biosynthesis, PE => PC [PATH:aam00564]
aam_M00092  Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE [PATH:aam00564]
Other DBs
GO: 0006650
Organism
Apteryx mantelli mantelli (North Island brown kiwi) [GN:aam]
Gene
106482628  PLA2G10; phospholipase A2 group X [KO:K01047] [EC:3.1.1.4]
106483097  PLD4; phospholipase D family member 4 [KO:K16860] [EC:3.1.4.4]
106483279  PLA2G15; phospholipase A2 group XV [KO:K06129] [EC:3.1.1.5]
106483282  LPCAT2; lysophosphatidylcholine acyltransferase 2 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
106483565  DGKB; diacylglycerol kinase beta [KO:K00901] [EC:2.7.1.107]
106483680  AGPAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
106483729  GPAM; glycerol-3-phosphate acyltransferase, mitochondrial [KO:K00629] [EC:2.3.1.15]
106483771  AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2 [KO:K13509] [EC:2.3.1.51]
106483906  PTDSS1; phosphatidylserine synthase 1 [KO:K08729] [EC:2.7.8.-]
106483980  [KO:K14156] [EC:2.7.1.32 2.7.1.82]
106484459  DGKD; diacylglycerol kinase delta [KO:K00901] [EC:2.7.1.107]
106484516  LCAT; lecithin-cholesterol acyltransferase [KO:K00650] [EC:2.3.1.43]
106484636  LPIN2; lipin 2 [KO:K15728] [EC:3.1.3.4]
106484868  ETNK2; ethanolamine kinase 2 [KO:K00894] [EC:2.7.1.82]
106485470  PLB1; phospholipase B1 [KO:K14621] [EC:3.1.1.4 3.1.1.5]
106485603  [KO:K00901] [EC:2.7.1.107]
106485642  CEPT1; choline/ethanolamine phosphotransferase 1 [KO:K13644] [EC:2.7.8.1 2.7.8.2]
106486026  PLA2G4A; phospholipase A2 group IVA [KO:K16342] [EC:3.1.1.4]
106486034  CDS2; CDP-diacylglycerol synthase 2 [KO:K00981] [EC:2.7.7.41]
106486035  [KO:K00981] [EC:2.7.7.41]
106486263  PLA2G1B; phospholipase A2 group IB [KO:K01047] [EC:3.1.1.4]
106486295  PISD; phosphatidylserine decarboxylase [KO:K01613] [EC:4.1.1.65]
106486389  [KO:K01080] [EC:3.1.3.4]
106486390  [KO:K01080] [EC:3.1.3.4]
106486554  GPD2; glycerol-3-phosphate dehydrogenase 2 [KO:K00111] [EC:1.1.5.3]
106486569  [KO:K01115] [EC:3.1.4.4]
106486823  AGPAT4; 1-acylglycerol-3-phosphate O-acyltransferase 4 [KO:K13523] [EC:2.3.1.51 2.3.1.-]
106486904  DGKQ; diacylglycerol kinase theta [KO:K00901] [EC:2.7.1.107]
106487132  PGS1; phosphatidylglycerophosphate synthase 1 [KO:K00995] [EC:2.7.8.5]
106487137  PCYT2; phosphate cytidylyltransferase 2, ethanolamine [KO:K00967] [EC:2.7.7.14]
106487305  PEMT; phosphatidylethanolamine N-methyltransferase [KO:K00551] [EC:2.1.1.17 2.1.1.71]
106487366  GNPAT; glyceronephosphate O-acyltransferase [KO:K00649] [EC:2.3.1.42]
106487418  PLA2G3; phospholipase A2 group III [KO:K01047] [EC:3.1.1.4]
106487492  [KO:K14676] [EC:3.1.1.5]
106487783  GPAT4; glycerol-3-phosphate acyltransferase 4 [KO:K13506] [EC:2.3.1.15]
106488208  LPIN3; lipin 3 [KO:K15728] [EC:3.1.3.4]
106488387  DGKI; diacylglycerol kinase iota [KO:K00901] [EC:2.7.1.107]
106488652  CHPT1; choline phosphotransferase 1 [KO:K00994] [EC:2.7.8.2]
106488934  PLA2G6; phospholipase A2 group VI [KO:K16343] [EC:3.1.1.4]
106488938  ETNK1; ethanolamine kinase 1 [KO:K00894] [EC:2.7.1.82]
106489083  SGMS1; sphingomyelin synthase 1 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
106489130  PTDSS2; phosphatidylserine synthase 2 [KO:K08730] [EC:2.7.8.29]
106489247  DGKH; diacylglycerol kinase eta [KO:K00901] [EC:2.7.1.107]
106489418  SELENOI; selenoprotein I [KO:K00993] [EC:2.7.8.1]
106490433  LCLAT1; lysocardiolipin acyltransferase 1 [KO:K13513] [EC:2.3.1.- 2.3.1.51]
106490445  LPGAT1; lysophosphatidylglycerol acyltransferase 1 [KO:K13514] [EC:2.3.1.-]
106490603  PLA1A; phospholipase A1 member A [KO:K13618] [EC:3.1.1.111]
106490609  [KO:K01047] [EC:3.1.1.4]
106491170  PCYT1B; phosphate cytidylyltransferase 1, choline, beta [KO:K00968] [EC:2.7.7.15]
106491245  GPD1L; glycerol-3-phosphate dehydrogenase 1-like [KO:K00006] [EC:1.1.1.8]
106491836  PLA2G12A; phospholipase A2 group XIIA [KO:K01047] [EC:3.1.1.4]
106491893  ETNPPL; ethanolamine-phosphate phospho-lyase [KO:K14286] [EC:4.2.3.2]
106491991  SGMS2; sphingomyelin synthase 2 [KO:K04714] [EC:2.7.8.27 2.7.8.48 3.1.4.62]
106492898  LPCAT1; lysophosphatidylcholine acyltransferase 1 [KO:K13510] [EC:2.3.1.23 2.3.1.67]
106493018  PNPLA7; patatin like phospholipase domain containing 7 [KO:K14676] [EC:3.1.1.5]
106493040  PLPP5; phospholipid phosphatase 5 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
106493111  DGKE; diacylglycerol kinase epsilon [KO:K00901] [EC:2.7.1.107]
106493229  AGPAT5; 1-acylglycerol-3-phosphate O-acyltransferase 5 [KO:K19007] [EC:2.3.1.51]
106493304  LYPLA2; lysophospholipase II [KO:K06130] [EC:3.1.1.5]
106493419  [KO:K01047] [EC:3.1.1.4]
106493421  [KO:K01047] [EC:3.1.1.4]
106493721  PLD3; phospholipase D family member 3 [KO:K16860] [EC:3.1.4.4]
106493807  GPAT2; glycerol-3-phosphate acyltransferase 2, mitochondrial [KO:K00629] [EC:2.3.1.15]
106494470  LYPLA1; lysophospholipase I [KO:K06128] [EC:3.1.1.5]
106494473  [KO:K00993] [EC:2.7.8.1]
106494724  MBOAT2; membrane bound O-acyltransferase domain containing 2 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
106494727  LPIN1; lipin 1 [KO:K15728] [EC:3.1.3.4]
106494817  CDS1; CDP-diacylglycerol synthase 1 [KO:K00981] [EC:2.7.7.41]
106494834  [KO:K13506] [EC:2.3.1.15]
106494838  [KO:K13506] [EC:2.3.1.15]
106494857  CHKA; choline kinase alpha [KO:K14156] [EC:2.7.1.32 2.7.1.82]
106495963  PHOSPHO1; phosphoethanolamine/phosphocholine phosphatase [KO:K06124] [EC:3.1.3.75]
106496109  [KO:K13509] [EC:2.3.1.51]
106496644  ACHE; acetylcholinesterase (Cartwright blood group) [KO:K01049] [EC:3.1.1.7]
106496876  ADPRM; ADP-ribose/CDP-alcohol diphosphatase, manganese dependent [KO:K01517] [EC:3.6.1.13 3.6.1.16 3.6.1.53]
106497265  LPCAT3; lysophosphatidylcholine acyltransferase 3 [KO:K13515] [EC:2.3.1.23 2.3.1.-]
106497401  [KO:K00901] [EC:2.7.1.107]
106497448  AGPAT1; 1-acylglycerol-3-phosphate O-acyltransferase 1 [KO:K13509] [EC:2.3.1.51]
106497480  TAZ; tafazzin [KO:K13511] [EC:2.3.1.-]
106498104  [KO:K16342] [EC:3.1.1.4]
106498106  [KO:K16342] [EC:3.1.1.4]
106498151  [KO:K16342] [EC:3.1.1.4]
106498152  [KO:K16342] [EC:3.1.1.4]
106498154  PLA2G4F; phospholipase A2 group IVF [KO:K16342] [EC:3.1.1.4]
106498170  [KO:K16342] [EC:3.1.1.4]
106498179  PLA2G4E; phospholipase A2 group IVE [KO:K16342] [EC:3.1.1.4]
106498182  [KO:K16342] [EC:3.1.1.4]
106498213  [KO:K16342] [EC:3.1.1.4]
106498236  PCYT1A; phosphate cytidylyltransferase 1, choline, alpha [KO:K00968] [EC:2.7.7.15]
106498296  DGKZ; diacylglycerol kinase zeta [KO:K00901] [EC:2.7.1.107]
106498487  [KO:K00006] [EC:1.1.1.8]
106498586  PLA2G12B; phospholipase A2 group XIIB [KO:K01047] [EC:3.1.1.4]
106498954  SAMD8; sterile alpha motif domain containing 8 [KO:K22697] [EC:2.7.8.48 3.1.4.62]
106499015  PLPP4; phospholipid phosphatase 4 [KO:K18693] [EC:3.6.1.75 3.1.3.4]
106499434  GPD1; glycerol-3-phosphate dehydrogenase 1 [KO:K00006] [EC:1.1.1.8]
106499795  GPCPD1; glycerophosphocholine phosphodiesterase 1 [KO:K18695] [EC:3.1.4.2]
106499833  PLPP3; phospholipid phosphatase 3 [KO:K01080] [EC:3.1.3.4]
106499854  CRLS1; cardiolipin synthase 1 [KO:K08744] [EC:2.7.8.41]
106499858  CHAT; choline O-acetyltransferase [KO:K00623] [EC:2.3.1.6]
106500318  [KO:K00551] [EC:2.1.1.17 2.1.1.71]
106500329  MBOAT1; membrane bound O-acyltransferase domain containing 1 [KO:K13517] [EC:2.3.1.51 2.3.1.-]
Compound
C00040  Acyl-CoA
C00065  L-Serine
C00084  Acetaldehyde
C00093  sn-Glycerol 3-phosphate
C00111  Glycerone phosphate
C00114  Choline
C00157  Phosphatidylcholine
C00189  Ethanolamine
C00269  CDP-diacylglycerol
C00307  CDP-choline
C00344  Phosphatidylglycerol
C00346  Ethanolamine phosphate
C00350  Phosphatidylethanolamine
C00416  Phosphatidate
C00513  CDP-glycerol
C00570  CDP-ethanolamine
C00588  Choline phosphate
C00623  sn-Glycerol 1-phosphate
C00641  1,2-Diacyl-sn-glycerol
C00670  sn-Glycero-3-phosphocholine
C00681  1-Acyl-sn-glycerol 3-phosphate
C01194  1-Phosphatidyl-D-myo-inositol
C01210  N-Methylethanolamine phosphate
C01233  sn-Glycero-3-phosphoethanolamine
C01241  Phosphatidyl-N-methylethanolamine
C01996  Acetylcholine
C02737  Phosphatidylserine
C03372  Acylglycerone phosphate
C03819  1-Acylglycerophosphoinositol
C03872  L-Serine-phosphoethanolamine
C03892  Phosphatidylglycerophosphate
C03974  2-Acyl-sn-glycerol 3-phosphate
C04230  1-Acyl-sn-glycero-3-phosphocholine
C04233  2-Acyl-sn-glycero-3-phosphocholine
C04308  Phosphatidyl-N-dimethylethanolamine
C04438  1-Acyl-sn-glycero-3-phosphoethanolamine
C04590  3-(O-Geranylgeranyl)-sn-glycerol 1-phosphate
C04638  2,3-Bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate
C05973  2-Acyl-sn-glycero-3-phosphoethanolamine
C05974  2-Acyl-sn-glycero-3-phosphoserine
C05976  Aminoacyl-phosphatidylglycerol
C05980  Cardiolipin
C06771  Triethanolamine
C06772  Diethanolamine
C13482  Phosphodimethylethanolamine
C18059  CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol
C18125  1-Acyl-sn-glycero-3-phosphoserine
C18126  1-Acyl-sn-glycero-3-phosphoglycerol
C18129  Monolysocardiolipin
C18168  Diacylglycerylhomoserine
C18169  Diacylglyceryl-N,N,N-trimethylhomoserine
C20466  2,3-Bis-(O-geranylgeranyl)-sn-glycero-1-phospho-L-serine
C20518  2,3-Bis-(O-phytanyl)-sn-glycerol 1-phosphate
C22340  Heptaprenylglyceryl phosphate
C22341  Heptaprenylglycerol
C22342  Diacetylheptaprenylglycerol
Reference
PMID:1512203
  Authors
Racenis PV, Lai JL, Das AK, Mullick PC, Hajra AK, Greenberg ML.
  Title
The acyl dihydroxyacetone phosphate pathway enzymes for glycerolipid biosynthesis are present in the yeast Saccharomyces cerevisiae.
  Journal
J Bacteriol 174:5702-10 (1992)
DOI:10.1128/JB.174.17.5702-5710.1992
Reference
PMID:10092508
  Authors
Taniyama Y, Shibata S, Kita S, Horikoshi K, Fuse H, Shirafuji H, Sumino Y, Fujino M.
  Title
Cloning and expression of a novel lysophospholipase which structurally resembles lecithin cholesterol acyltransferase.
  Journal
Biochem Biophys Res Commun 257:50-6 (1999)
DOI:10.1006/bbrc.1999.0411
Reference
PMID:10542045
  Authors
Athenstaedt K, Daum G.
  Title
Phosphatidic acid, a key intermediate in lipid metabolism.
  Journal
Eur J Biochem 266:1-16 (1999)
DOI:10.1046/j.1432-1327.1999.00822.x
Reference
PMID:12431977
  Authors
Shields DJ, Lehner R, Agellon LB, Vance DE.
  Title
Membrane topography of human phosphatidylethanolamine N-methyltransferase.
  Journal
J Biol Chem 278:2956-62 (2003)
DOI:10.1074/jbc.M210904200
Reference
PMID:14663079
  Authors
Martinez-Morales F, Schobert M, Lopez-Lara IM, Geiger O.
  Title
Pathways for phosphatidylcholine biosynthesis in bacteria.
  Journal
Microbiology 149:3461-71 (2003)
DOI:10.1099/mic.0.26522-0
Reference
PMID:15522832
  Authors
Burgermeister M, Birner-Grunberger R, Nebauer R, Daum G.
  Title
Contribution of different pathways to the supply of phosphatidylethanolamine and phosphatidylcholine to mitochondrial membranes of the yeast Saccharomyces cerevisiae.
  Journal
Biochim Biophys Acta 1686:161-8 (2004)
DOI:10.1016/j.bbalip.2004.09.007
Reference
PMID:1649829
  Authors
Hsu L, Jackowski S, Rock CO
  Title
Isolation and characterization of Escherichia coli K-12 mutants lacking both 2-acyl-glycerophosphoethanolamine acyltransferase and acyl-acyl carrier protein synthetase activity.
  Journal
J Biol Chem 266:13783-8 (1991)
Reference
PMID:10938271
  Authors
Stone SJ, Vance JE.
  Title
Phosphatidylserine synthase-1 and -2 are localized to mitochondria-associated membranes.
  Journal
J Biol Chem 275:34534-40 (2000)
DOI:10.1074/jbc.M002865200
Related
pathway
aam00010  Glycolysis / Gluconeogenesis
aam00260  Glycine, serine and threonine metabolism
aam00561  Glycerolipid metabolism
aam00562  Inositol phosphate metabolism
aam00563  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
aam00565  Ether lipid metabolism
aam00620  Pyruvate metabolism
KO pathway
ko00564   

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