KEGG   PATHWAY: aih00230
Entry
aih00230                    Pathway                                
Name
Purine metabolism - Actinoplanes ianthinogenes
Class
Metabolism; Nucleotide metabolism
Pathway map
aih00230  Purine metabolism
aih00230

Module
aih_M00005  PRPP biosynthesis, ribose 5P => PRPP [PATH:aih00230]
aih_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP [PATH:aih00230]
aih_M00049  Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:aih00230]
aih_M00050  Guanine ribonucleotide biosynthesis, IMP => GDP,GTP [PATH:aih00230]
aih_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP [PATH:aih00230]
aih_M00546  Purine degradation, xanthine => urea [PATH:aih00230]
aih_M00958  Adenine ribonucleotide degradation, AMP => Urate [PATH:aih00230]
Other DBs
GO: 0006163 0042278
Organism
Actinoplanes ianthinogenes [GN:aih]
Gene
Aiant_00620  [KO:K07816] [EC:2.7.6.5]
Aiant_00710  [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Aiant_01150  purN_1; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Aiant_03420  [KO:K00526] [EC:1.17.4.1]
Aiant_03950  [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Aiant_20400  adk_1; adenylate kinase [KO:K00939] [EC:2.7.4.3]
Aiant_21530  gmk; guanylate kinase [KO:K00942] [EC:2.7.4.8]
Aiant_22060  ureA; urease subunit gamma [KO:K01430] [EC:3.5.1.5]
Aiant_22070  ureB; urease subunit beta [KO:K01429] [EC:3.5.1.5]
Aiant_22080  ureC; urease subunit alpha [KO:K01428] [EC:3.5.1.5]
Aiant_22290  relA; GTP pyrophosphokinase [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Aiant_22300  apt_1; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Aiant_22480  [KO:K19710] [EC:2.7.7.53]
Aiant_23840  alc; putative allantoicase [KO:K01477] [EC:3.5.3.4]
Aiant_23850  allB; allantoinase [KO:K01466] [EC:3.5.2.5]
Aiant_23910  [KO:K00365] [EC:1.7.3.3]
Aiant_23920  [KO:K07127] [EC:3.5.2.17]
Aiant_23930  [KO:K16840] [EC:4.1.1.97]
Aiant_25120  purA_1; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Aiant_25410  prsA_1; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Aiant_25600  [KO:K07127] [EC:3.5.2.17]
Aiant_28780  dgt_1; dGTPase [KO:K01129] [EC:3.1.5.1]
Aiant_29730  nrdA; ribonucleoside-diphosphate reductase subunit alpha [KO:K00525] [EC:1.17.4.1]
Aiant_36200  add1; adenosine deaminase 1 [KO:K01488] [EC:3.5.4.4]
Aiant_36400  [KO:K00956] [EC:2.7.7.4]
Aiant_36410  [KO:K00957] [EC:2.7.7.4]
Aiant_36460  prsA_2; ribose-phosphate pyrophosphokinase [KO:K00948] [EC:2.7.6.1]
Aiant_39550  hpt; hypoxanthine phosphoribosyltransferase [KO:K00760] [EC:2.4.2.8]
Aiant_40110  deoD; purine nucleoside phosphorylase DeoD-type [KO:K03784] [EC:2.4.2.1]
Aiant_40490  purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [KO:K01923] [EC:6.3.2.6]
Aiant_43530  apt_2; adenine phosphoribosyltransferase [KO:K00759] [EC:2.4.2.7]
Aiant_44050  purA_2; adenylosuccinate synthetase [KO:K01939] [EC:6.3.4.4]
Aiant_44060  purD; phosphoribosylamine--glycine ligase [KO:K01945] [EC:6.3.4.13]
Aiant_44100  [KO:K01756] [EC:4.3.2.2]
Aiant_44110  purS; phosphoribosylformylglycinamidine synthase subunit PurS [KO:K23264]
Aiant_44120  purL_1; phosphoribosylformylglycinamidine synthase subunit PurQ [KO:K23265]
Aiant_44130  purL_2; phosphoribosylformylglycinamidine synthase subunit PurL [KO:K23269]
Aiant_44160  purF; amidophosphoribosyltransferase [KO:K00764] [EC:2.4.2.14]
Aiant_44170  purM; phosphoribosylformylglycinamidine cyclo-ligase [KO:K01933] [EC:6.3.3.1]
Aiant_47620  [KO:K00525] [EC:1.17.4.1]
Aiant_47630  nrdB; ribonucleoside-diphosphate reductase subunit beta [KO:K00526] [EC:1.17.4.1]
Aiant_49650  adk_2; adenylate kinase [KO:K00939] [EC:2.7.4.3]
Aiant_50290  guaB_1; inosine-5'-monophosphate dehydrogenase [KO:K00088] [EC:1.1.1.205]
Aiant_50300  guaB_2; IMP dehydrogenase [KO:K00088] [EC:1.1.1.205]
Aiant_50340  guaA_1; GMP synthase [glutamine-hydrolyzing] [KO:K01951] [EC:6.3.5.2]
Aiant_50490  [KO:K01081] [EC:3.1.3.5]
Aiant_50590  purN_2; phosphoribosylglycinamide formyltransferase [KO:K11175] [EC:2.1.2.2]
Aiant_50600  purH; bifunctional purine biosynthesis protein PurH [KO:K00602] [EC:2.1.2.3 3.5.4.10]
Aiant_50810  sopT; sulfate adenylyltransferase [KO:K00958] [EC:2.7.7.4]
Aiant_51000  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Aiant_51390  purK; N5-carboxyaminoimidazole ribonucleotide synthase [KO:K01589] [EC:6.3.4.18]
Aiant_51400  purE; N5-carboxyaminoimidazole ribonucleotide mutase [KO:K01588] [EC:5.4.99.18]
Aiant_53370  [KO:K01519] [EC:3.6.1.66]
Aiant_53740  [KO:K00942] [EC:2.7.4.8]
Aiant_55710  ndk; nucleoside diphosphate kinase [KO:K00940] [EC:2.7.4.6]
Aiant_56690  dgt_2; deoxyguanosinetriphosphate triphosphohydrolase-like protein [KO:K01129] [EC:3.1.5.1]
Aiant_57500  [KO:K01119] [EC:3.1.4.16 3.1.3.6]
Aiant_57560  surE; 5'/3'-nucleotidase SurE [KO:K03787] [EC:3.1.3.5 3.1.3.6]
Aiant_58980  [KO:K00856] [EC:2.7.1.20]
Aiant_59170  [KO:K01139] [EC:2.7.6.5 3.1.7.2]
Aiant_61810  [KO:K16841] [EC:5.1.99.3]
Aiant_62640  [KO:K02566] [EC:3.1.3.5]
Aiant_64240  arcC-2; carbamate kinase [KO:K00926] [EC:2.7.2.2]
Aiant_74530  [KO:K01835] [EC:5.4.2.2]
Aiant_75850  [KO:K11177] [EC:1.17.1.4]
Aiant_75860  [KO:K11178] [EC:1.17.1.4]
Aiant_75870  [KO:K13483]
Aiant_82260  [KO:K01524] [EC:3.6.1.11 3.6.1.40]
Aiant_83310  [KO:K22879] [EC:1.14.13.113]
Aiant_86020  [KO:K03651] [EC:3.1.4.53]
Aiant_87790  [KO:K00759] [EC:2.4.2.7]
Compound
C00002  ATP
C00008  ADP
C00011  CO2
C00014  Ammonia
C00020  AMP
C00035  GDP
C00037  Glycine
C00039  DNA
C00044  GTP
C00046  RNA
C00048  Glyoxylate
C00053  3'-Phosphoadenylyl sulfate
C00054  Adenosine 3',5'-bisphosphate
C00059  Sulfate
C00064  L-Glutamine
C00081  ITP
C00086  Urea
C00104  IDP
C00117  D-Ribose 5-phosphate
C00119  5-Phospho-alpha-D-ribose 1-diphosphate
C00130  IMP
C00131  dATP
C00144  GMP
C00147  Adenine
C00169  Carbamoyl phosphate
C00206  dADP
C00209  Oxalate
C00212  Adenosine
C00224  Adenylyl sulfate
C00242  Guanine
C00262  Hypoxanthine
C00286  dGTP
C00288  HCO3-
C00294  Inosine
C00301  ADP-ribose
C00330  Deoxyguanosine
C00360  dAMP
C00361  dGDP
C00362  dGMP
C00366  Urate
C00385  Xanthine
C00387  Guanosine
C00499  Allantoate
C00559  Deoxyadenosine
C00575  3',5'-Cyclic AMP
C00603  (S)-Ureidoglycolate
C00620  alpha-D-Ribose 1-phosphate
C00655  Xanthosine 5'-phosphate
C00700  XTP
C00802  Oxalureate
C00942  3',5'-Cyclic GMP
C01228  Guanosine 3',5'-bis(diphosphate)
C01260  P1,P4-Bis(5'-adenosyl)tetraphosphate
C01261  P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  dIDP
C01345  dITP
C01367  3'-AMP
C01444  Oxamate
C01762  Xanthosine
C02091  (S)-Ureidoglycine
C02348  (R)(-)-Allantoin
C02350  (S)-Allantoin
C02353  2',3'-Cyclic AMP
C02718  N-Formiminoglycine
C03090  5-Phosphoribosylamine
C03373  Aminoimidazole ribotide
C03483  Adenosine tetraphosphate
C03614  Inosine 5'-tetraphosphate
C03794  N6-(1,2-Dicarboxyethyl)-AMP
C03838  5'-Phosphoribosylglycinamide
C04051  5-Amino-4-imidazolecarboxyamide
C04376  5'-Phosphoribosyl-N-formylglycinamide
C04392  P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  Guanosine 3'-diphosphate 5'-triphosphate
C04640  2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  5-Aminoimidazole
C05512  Deoxyinosine
C05513  Urate-3-ribonucleoside
C05515  5-Ureido-4-imidazole carboxylate
C05516  5-Amino-4-imidazole carboxylate
C05993  Acetyl adenylate
C06193  Guanosine 3'-phosphate
C06194  2',3'-Cyclic GMP
C06195  Imidazolone
C06196  2'-Deoxyinosine 5'-phosphate
C06197  P1,P3-Bis(5'-adenosyl) triphosphate
C06433  5'-Benzoylphosphoadenosine
C06435  5'-Butyrylphosphoinosine
C11821  5-Hydroxyisourate
C12248  5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
C22395  N6-Succino-2-amino-2'-deoxyadenylate
C22441  dZMP
C22442  dZDP
C22443  dZTP
C22499  8-Hydroxyadenine
C22500  2,8-Dihydroxyadenine
Reference
PMID:10601204
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
DOI:10.1128/JB.181.24.7479-7484.1999
Reference
PMID:10986234
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
DOI:10.1128/JB.182.19.5332-5341.2000
Related
pathway
aih00030  Pentose phosphate pathway
aih00220  Arginine biosynthesis
aih00250  Alanine, aspartate and glutamate metabolism
aih00260  Glycine, serine and threonine metabolism
aih00340  Histidine metabolism
aih00630  Glyoxylate and dicarboxylate metabolism
aih00730  Thiamine metabolism
aih00740  Riboflavin metabolism
aih00790  Folate biosynthesis
KO pathway
ko00230   

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